The membrane processes have received extensive attention as comprehensive and interdisciplinary approaches for water-energy nexus. Nanotechnology has induced significant attention in improving membrane performances to mitigate global water and energy scarcity because of its unique characteristics and simple application for membrane fabrication. Nano-sized materials could provide highly enhanced characteristics to a membrane material, resulting in excellent performance enhancement, such as permeability, selectivity, and fouling resistance, of membrane. Carbon Nanotube (CNT), a widely utilized or studied nanomaterial in membrane science, is discussed in this chapter with a focus on its state-of-the-art applications and future prospects. Electrospun nanofiber, which is one of the feasible nano-structured membrane materials, is also discussed as a promising material for water-energy nexus. Therefore, this chapter also describes its application cases and its potential as an innovative membrane for water-energy nexus.