scholarly journals A microporous walled micro-capillary film module for cation-exchange protein chromatography

2014 ◽  
Vol 466 ◽  
pp. 123-129 ◽  
Author(s):  
I. Mandal ◽  
M.J. Townsend ◽  
N.J. Darton ◽  
S. Bonyadi ◽  
N.K.H. Slater
Keyword(s):  
Cation Exchange ◽  
Protein Chromatography ◽  
Capillary Film ◽  
Exchange Protein

scholarly journals Synthesis of Strong Cation Exchange Macroporous Polymer Cluster for Convective Protein Chromatography

2019 ◽  
Vol 304 (10) ◽  
pp. 1900311
Author(s):  
Marcel Lorenz ◽  
Sebastian Vogg ◽  
Patrick Finkelstein ◽  
Giuseppe Storti ◽  
Massimo Morbidelli
Keyword(s):  
Cation Exchange ◽  
Protein Chromatography ◽  
Strong Cation Exchange

scholarly journals The development of a weak anion micro-capillary film for protein chromatography

2016 ◽  
Vol 1468 ◽  
pp. 64-72 ◽  
Author(s):  
A.J.M. Kouyoumdjian ◽  
R.A. Lazar ◽  
N.K.H. Slater
Keyword(s):  
Protein Chromatography ◽  
Capillary Film

Model-based high-throughput design of ion exchange protein chromatography

2016 ◽  
Vol 1459 ◽  
pp. 67-77 ◽  
Author(s):  
Rushd Khalaf ◽  
Julia Heymann ◽  
Xavier LeSaout ◽  
Florence Monard ◽  
Matteo Costioli ◽  
...  
Keyword(s):  
Ion Exchange ◽  
High Throughput ◽  
Protein Chromatography ◽  
Model Based ◽  
Exchange Protein

The Effect of Calcium and Magnesium on Rabbit Blood Platelet Aggregation in Vitro

1964 ◽  
Vol 12 (01) ◽  
pp. 179-200 ◽  
Author(s):  
Torstein Hovig
Keyword(s):  
Platelet Aggregation ◽  
Cation Exchange ◽  
Calcium Concentration ◽  
Blood Platelets ◽  
Blood Platelet ◽  
Rabbit Blood ◽  
Calcium And Magnesium ◽  
Induced Aggregation ◽  
Blood Platelet Aggregation

SummaryThe effect of calcium and magnesium on the aggregation of rabbit blood platelets in vitro was studied, with the following results:1. Platelet aggregation induced by ADP or collagen could be prevented by EGTA or EDTA. The aggregating effect was restored by recalcification. The effect was also restored by addition of magnesium in EDTA-PRP, but not in EGTA-PRP unless a surplus of calcium was present.2. Calcium remained in concentrations of the order of 0.15–0.25 mM after dialysis or cation exchange of plasma. Aggregation of washed platelets resuspended in such plasma could not be produced with ADP or collagen, unless the calcium concentration was increased or that magnesium was added.3. The adhesiveness of blood platelets to collagen was reduced in EGTA-PRP and EDTA-PRP. Release of ADP from platelets influenced by collagen could not be demonstrated either in EGTA-PRP (presence of magnesium) or in EDTA-PRP.4. It is concluded that calcium is a necessary factor both for the reaction leading to release of ADP and for the the aggregation produced by ADP.5. Thrombin induced aggregation of washed platelets suspended in tris-buffered saline in the presence of calcium. No effect of magnesium could be observed unless small quantities of calcium were present.

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