scholarly journals Evidence for organic cation transporter-mediated metformin transport and 5′-adenosine monophosphate-activated protein kinase activation in rat skeletal muscles

Metabolism ◽  
2015 ◽  
Vol 64 (2) ◽  
pp. 296-304 ◽  
Author(s):  
Rieko Oshima ◽  
Mayumi Yamada ◽  
Eriko Kurogi ◽  
Yohei Ogino ◽  
Yasuhiro Serizawa ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Skeletal Muscles ◽  
Organic Cation ◽  
Organic Cation Transporter ◽  
Adenosine Monophosphate ◽  
Kinase Activation ◽  
Protein Kinase Activation

scholarly journals Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation

2015 ◽  
Vol 194 (1) ◽  
pp. 262-272 ◽  
Author(s):  
Daniel A. Escobar ◽  
Ana M. Botero-Quintero ◽  
Benjamin C. Kautza ◽  
Jason Luciano ◽  
Patricia Loughran ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Adenosine Monophosphate ◽  
Organ Injury ◽  
Kinase Activation ◽  
Protein Kinase Activation

Cyclic AMP in action of antidiuretic hormone: effects of exogenous cyclic AMP and its new analogue

1977 ◽  
Vol 232 (4) ◽  
pp. F368-F376 ◽  
Author(s):  
D. A. Hall ◽  
L. D. Barnes ◽  
T. P. Dousa
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Antidiuretic Hormone ◽  
Kidney Tissue ◽  
Adenosine Monophosphate ◽  
Kinase Activation ◽  
Camp Generation ◽  
Protein Kinase Activation ◽  
Hormone Effects ◽  
Collecting Tubules

Exogenous cyclic 3',5'-adenosine monophosphate (cAMP) stimulates the effect of the antidiuretic hormone, vasopressin (VP), only in pharmacologic quantities and results have often been inconsistent. The present study examined the ability of a new analogue, 8-[p-Cl-phenylthio]cyclic 3',5'-adenosine monophosphate (C1-PheS-cAMP) to mimic the effect of VP, both biochemically (protein kinase activation) and functionally (hydrosomatic response of perfused collecting tubules) in mammalian kidney tissue. C1PheS-cAMP was found to be about 100 times as effective as cAMP both biochemically and functionally. The increased effectiveness of C1PheS-cAMP is probably is probably due to a greater permeability across the cell membrane and to the resistance of C1PheS-cAMP to enzymatic degradation, Cyclic AMP phosphodiesterase inhibition was observed with C1PheS-cAMP, but its contribution to overall effect was minor. C1PheS-cAMP was found to be more effective than exogenous vasopressin, an effect probably due primarily to its resistance to catabolism. The results provide further new evidence that cAMP and protein kinase are involved in the cellular action of vasopressin. C1PheS-cAMP proved to be a useful tool in the study of hormone action, especially in steps subsequent to cAMP generation.

scholarly journals MicroRNA-1285 Regulates 17β-Estradiol-Inhibited Immature Boar Sertoli Cell Proliferation via Adenosine Monophosphate-Activated Protein Kinase Activation

Endocrinology ◽  
2015 ◽  
Vol 156 (11) ◽  
pp. 4059-4070 ◽  
Author(s):  
Zhang Jiao Jiao ◽  
Wang Yi ◽  
Yang Wei Rong ◽  
Jeong Dong Kee ◽  
Wang Xian Zhong
Keyword(s):  
Cell Proliferation ◽  
Protein Kinase ◽  
Sertoli Cell ◽  
Adenosine Monophosphate ◽  
Kinase Activation ◽  
Protein Kinase Activation ◽  
17Β Estradiol

scholarly journals MicroRNA-7450 regulates non-thermal plasma-induced chicken Sertoli cell apoptosis via adenosine monophosphate-activated protein kinase activation

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Jiao Jiao Zhang ◽  
Xian Zhong Wang ◽  
Huynh Luong Do ◽  
Nisansala Chandimali ◽  
Tae Yoon Kang ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Sertoli Cell ◽  
Thermal Plasma ◽  
Cell Apoptosis ◽  
Adenosine Monophosphate ◽  
Kinase Activation ◽  
Protein Kinase Activation ◽  
Non Thermal Plasma

scholarly journals Purine analogue ENERGI-F706 induces apoptosis of 786-O renal carcinoma cells via 5′-adenosine monophosphate-activated protein kinase activation

2015 ◽  
Vol 12 (3) ◽  
pp. 4566-4571 ◽  
Author(s):  
CHAO-YU HSU ◽  
CHUN-HSIANG LIN ◽  
JIUN-TSAI LIN ◽  
YI-FANG CHENG ◽  
HAN-MIN CHEN ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Renal Carcinoma ◽  
Adenosine Monophosphate ◽  
Carcinoma Cells ◽  
Kinase Activation ◽  
Purine Analogue ◽  
Protein Kinase Activation ◽  
Renal Carcinoma Cells
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