Dual-Stage Amplified Fluorescent DNA Sensor Based on Polymerase-Mediated Strand Displacement Reactions

2021 ◽  
pp. 106946
Author(s):  
Shuyi He ◽  
Peng Li ◽  
Le Tang ◽  
Mingjian Chen ◽  
Yuxin Yang ◽  
...  
ChemPhysChem ◽  
2021 ◽  
Author(s):  
Hui Lv ◽  
Qian Li ◽  
Jiye Shi ◽  
Fei Wang ◽  
Chunhai Fan

Nanoscale ◽  
2015 ◽  
Vol 7 (30) ◽  
pp. 12970-12978 ◽  
Author(s):  
Ismael Mullor Ruiz ◽  
Jean-Michel Arbona ◽  
Amitkumar Lad ◽  
Oscar Mendoza ◽  
Jean-Pierre Aimé ◽  
...  

Design and characterization of a DNA-based localized amplification circuit which, upon tethering on a DNA origami platform, greatly accelerates the catalytic response.


2016 ◽  
Vol 8 (37) ◽  
pp. 6701-6704 ◽  
Author(s):  
Chenxi Li ◽  
Ruoyun Lin ◽  
Tian Li ◽  
Feng Liu ◽  
Na Li

Binding-induced DNA strand-displacement reactions diversify the applications beyond nucleic acids and small molecules.


2017 ◽  
Vol 7 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Jonathan Lloyd ◽  
Claire H. Tran ◽  
Krishen Wadhwani ◽  
Christian Cuba Samaniego ◽  
Hari K. K. Subramanian ◽  
...  

2011 ◽  
Vol 8 (62) ◽  
pp. 1281-1297 ◽  
Author(s):  
Lulu Qian ◽  
Erik Winfree

The prospects of programming molecular systems to perform complex autonomous tasks have motivated research into the design of synthetic biochemical circuits. Of particular interest to us are cell-free nucleic acid systems that exploit non-covalent hybridization and strand displacement reactions to create cascades that implement digital and analogue circuits. To date, circuits involving at most tens of gates have been demonstrated experimentally. Here, we propose a simple DNA gate architecture that appears suitable for practical synthesis of large-scale circuits involving possibly thousands of gates.


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