Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells: Biochemical evidence and therapeutic perspectives

Christian Borgo; Luca Cesaro; Valentina Salizzato; Maria Ruzzene; Maria Lina Massimino; Lorenzo A. Pinna; Arianna Donella-Deana

doi:10.1016/j.molonc.2013.08.006

Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells: Biochemical evidence and therapeutic perspectives

Molecular Oncology ◽

10.1016/j.molonc.2013.08.006 ◽

2013 ◽

Vol 7 (6) ◽

pp. 1103-1115 ◽

Cited By ~ 23

Author(s):

Christian Borgo ◽

Luca Cesaro ◽

Valentina Salizzato ◽

Maria Ruzzene ◽

Maria Lina Massimino ◽

...

Keyword(s):

Protein Kinase ◽

Chronic Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Protein Kinase Ck2 ◽

Biochemical Evidence ◽

Imatinib Resistant ◽

Kinase Ck2

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Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies

Oncotarget ◽

10.18632/oncotarget.7569 ◽

2016 ◽

Vol 7 (14) ◽

pp. 18204-18218 ◽

Cited By ~ 12

Author(s):

Valentina Salizzato ◽

Christian Borgo ◽

Luca Cesaro ◽

Lorenzo A. Pinna ◽

Arianna Donella-Deana

Keyword(s):

Protein Kinase ◽

Chronic Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Protein Kinase Ck2 ◽

Therapeutic Strategies ◽

Imatinib Resistance ◽

Rps6 Phosphorylation ◽

Kinase Ck2

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Biochemical evidence that the N-terminal segments of the α subunit and the β subunit play interchangeable roles in the activation of protein kinase CK2

FEBS Letters ◽

10.1016/s0014-5793(98)01516-6 ◽

1998 ◽

Vol 441 (1) ◽

pp. 29-33 ◽

Cited By ~ 13

Author(s):

Stefania Sarno ◽

Oriano Marin ◽

Paola Ghisellini ◽

Flavio Meggio ◽

Lorenzo A Pinna

Keyword(s):

Protein Kinase ◽

Protein Kinase Ck2 ◽

Β Subunit ◽

Α Subunit ◽

Biochemical Evidence ◽

Kinase Ck2

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Nuclear Matrix and Protein Kinase CK2 Signaling

Critical Reviews in Eukaryotic Gene Expression ◽

10.1615/critreveukargeneexpr.v9.i3-4.170 ◽

1999 ◽

Vol 9 (3-4) ◽

pp. 329-336 ◽

Cited By ~ 35

Author(s):

Khalil Ahmed

Keyword(s):

Protein Kinase ◽

Nuclear Matrix ◽

Protein Kinase Ck2 ◽

Kinase Ck2

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Faculty Opinions recommendation of Regulation of azole drug susceptibility by Candida albicans protein kinase CK2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025399.299723 ◽

2005 ◽

Author(s):

Miguel Penalva

Keyword(s):

Candida Albicans ◽

Protein Kinase ◽

Protein Kinase Ck2 ◽

Drug Susceptibility ◽

Kinase Ck2

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Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the ΔF508 mutation. F508 deletion disrupts a kinase-binding site. VOLUME 282 (2007) PAGES 10804-10813

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)49254-5 ◽

2008 ◽

Vol 283 (36) ◽

pp. 25103

Author(s):

Kate J. Treharne ◽

Russell M. Crawford ◽

Zhe Xu ◽

Jeng-Haur Chen ◽

O. Giles Best ◽

...

Keyword(s):

Cystic Fibrosis ◽

Protein Kinase ◽

Binding Site ◽

Protein Kinase Ck2 ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Kinase Ck2 ◽

Cystic Fibrosis Transmembrane

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Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113223 ◽

2021 ◽

Vol 214 ◽

pp. 113223

Author(s):

Alexander Schnitzler ◽

Karsten Niefind

Keyword(s):

Protein Kinase ◽

Protein Kinase Ck2 ◽

Competitive Inhibitor ◽

Structural Basis ◽

Complex Structures ◽

Kinase Ck2 ◽

Bisubstrate Inhibitors

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The catalytic subunit of protein kinase CK2 phosphorylates in vitro the movement protein of Tomato mosaic virus

Journal of General Virology ◽

10.1099/vir.0.18839-0 ◽

2003 ◽

Vol 84 (2) ◽

pp. 497-505 ◽

Cited By ~ 30

Author(s):

Yasuhiko Matsushita ◽

Mayumi Ohshima ◽

Kuniaki Yoshioka ◽

Masamichi Nishiguchi ◽

Hiroshi Nyunoya

Keyword(s):

Protein Kinase ◽

Mosaic Virus ◽

Protein Kinase Ck2 ◽

Movement Protein ◽

Catalytic Subunit ◽

Tomato Mosaic Virus ◽

Kinase Ck2

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Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.

BMC Biochemistry ◽

10.1186/1471-2091-10-36 ◽

2009 ◽

Vol 10 (1) ◽

pp. 36 ◽

Cited By ~ 36

Author(s):

Christopher C Williams ◽

Aninda Basu ◽

Abeer El-Gharbawy ◽

Latonya M Carrier ◽

Carolyn L Smith ◽

...

Keyword(s):

Gene Expression ◽

Estrogen Receptor ◽

Protein Kinase ◽

Protein Kinase Ck2 ◽

Estrogen Receptor Alpha ◽

Phosphorylation Sites ◽

Receptor Alpha ◽

Kinase Ck2

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Yeast surviving factor Svf1 as a new interacting partner, regulator and in vitro substrate of protein kinase CK2

Molecular and Cellular Biochemistry ◽

10.1007/s11010-008-9721-9 ◽

2008 ◽

Vol 312 (1-2) ◽

pp. 61-69 ◽

Cited By ~ 4

Author(s):

Maciej Masłyk ◽

Elżbieta Kochanowicz ◽

Rafał Zieliński ◽

Konrad Kubiński ◽

Ulf Hellman ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase Ck2 ◽

Kinase Ck2

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Protein kinase CK2: evidence for a protein kinase CK2β subunit fraction, devoid of the catalytic CK2α subunit, in mouse brain and testicles

FEBS Letters ◽

10.1016/s0014-5793(99)01553-7 ◽

1999 ◽

Vol 462 (3) ◽

pp. 353-357 ◽

Cited By ~ 77

Author(s):

Barbara Guerra ◽

Stefan Siemer ◽

Brigitte Boldyreff ◽

Olaf-Georg Issinger

Keyword(s):

Protein Kinase ◽

Mouse Brain ◽

Protein Kinase Ck2 ◽

Catalytic Ck2α Subunit ◽

Kinase Ck2

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