Nonlinear optical studies and structure-activity relationship of chalcone derivatives with in silico insights

2017 ◽  
Vol 1139 ◽  
pp. 294-302 ◽  
Author(s):  
Swayamsiddha Kar ◽  
K.S. Adithya ◽  
Pruthvik Shankar ◽  
N. Jagadeesh Babu ◽  
Sailesh Srivastava ◽  
...  
Keyword(s):  
In Silico ◽  
Nonlinear Optical ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Optical Studies ◽  
Chalcone Derivatives ◽  
Structure Activity ◽  
Relationship Of

Structure−Activity Relationship of New Nonlinear Optical Organic Materials Based on Push−Pull Azo Dyes. 3. Guest−Host Systems

1998 ◽  
Vol 31 (7) ◽  
pp. 2152-2159 ◽  
Author(s):  
N. Tirelli ◽  
U. W. Suter ◽  
A. Altomare ◽  
R. Solaro ◽  
F. Ciardelli ◽  
...  
Keyword(s):  
Azo Dyes ◽  
Nonlinear Optical ◽  
Organic Materials ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

scholarly journals In Silico Exploration for Identifying Structure-Activity Relationship of MEK Inhibition and Oral Bioavailability for Isothiazole Derivatives

2010 ◽  
Vol 76 (5) ◽  
pp. 397-406 ◽  
Author(s):  
Georgia Melagraki ◽  
Antreas Afantitis ◽  
Haralambos Sarimveis ◽  
Olga Igglessi-Markopoulou ◽  
Panayiotis A. Koutentis ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
In Silico ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Mek Inhibition ◽  
Structure Activity ◽  
Relationship Of

scholarly journals Structure-activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives

2019 ◽  
Vol 84 (7) ◽  
pp. 649-661 ◽  
Author(s):  
Muhammad Abbasi ◽  
Muhammad Ramzan ◽  
A Aziz-Ur-Rehman ◽  
Sabahat Siddiqui ◽  
Mubashir Hassan ◽  
...  
Keyword(s):  
In Silico ◽  
Acid Hydrazide ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Spectroscopic Techniques ◽  
Structure Activity ◽  
Hybrid Molecules ◽  
In Silico Study ◽  
Brine Shrimps ◽  
Relationship Of

This paper presents the synthesis of some unique bi-heterocyclic hybrid molecules with a thiazole and an oxadiazole ring. The synthesis was initiated by the conversion of ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate (1) to the corresponding 2-(2-amino-1,3-thiazol-4-yl)acetohydrazide (2) by the reaction with hydrazine hydrate in methanol. The treatment of the acid hydrazide, 2, with carbon disulfide gave the bi-heterocyclic nucleophile, 5-[(2-amino-1,3- -thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol (3). Finally, the target compounds, 5a?o, were synthesized by stirring the nucleophile 3 with different electrophiles, 4a?o, in DMF using LiH as a base and an activator. The structures of the newly synthesized molecules were confirmed through spectroscopic techniques, such as IR, EI-MS, 1H-NMR and 13C-NMR. The structure? ?activity relationship of all these bi-heterocycles was established by evaluating them against four enzymes, namely, acetylcholinesterase, butyrylcholinesterase, urease and ?-glucosidase, followed by their in silico study. Moreover, their cytotoxicity was also profiled by killing data of brine shrimps at various concentrations.

Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
MA Brenzan ◽  
CV Nakamura ◽  
BPD Filho ◽  
T Ueda-Nakamura ◽  
MCM Young ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Leishmania Amazonensis ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Structure Activity Relationship of Kahalalide F and its Analogs Against Fusarium Spp

Planta Medica ◽  
2008 ◽  
Vol 74 (03) ◽  
Author(s):  
N Kasanah ◽  
AG Shilabin ◽  
DE Wedge ◽  
MT Hamann
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Fusarium Spp ◽  
Structure Activity ◽  
Kahalalide F ◽  
Relationship Of
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