Synthetic T2-weighted images of the lumbar spine derived from an accelerated T2 mapping sequence: Comparison to conventional T2w turbo spin echo

2021 ◽  
Vol 84 ◽  
pp. 92-100
Author(s):  
Marcus Raudner ◽  
Daniel F Toth ◽  
Markus M Schreiner ◽  
Tom Hilbert ◽  
Tobias Kober ◽  
...  
2018 ◽  
Vol 29 (2) ◽  
pp. 223-230 ◽  
Author(s):  
Nico Sollmann ◽  
Dominik Weidlich ◽  
Barbara Cervantes ◽  
Elisabeth Klupp ◽  
Carl Ganter ◽  
...  

2015 ◽  
Vol 56 (2) ◽  
pp. 174-181 ◽  
Author(s):  
Sungwon Lee ◽  
Won-Hee Jee ◽  
Joon-Yong Jung ◽  
So-Yeon Lee ◽  
Kyeung-Sik Ryu ◽  
...  

2013 ◽  
Vol 15 (S1) ◽  
Author(s):  
Elsa Fernandes ◽  
Tamara Rothstein ◽  
Gabriel C Camargo ◽  
Daniel C Quintella ◽  
Maria Eduarda Derenne ◽  
...  

Author(s):  
Diana Bencikova ◽  
Fei Han ◽  
Stephan Kannengieser ◽  
Marcus Raudner ◽  
Sarah Poetter-Lang ◽  
...  

Abstract Objectives T2 mapping of the liver is a potential diagnostic tool, but conventional techniques are difficult to perform in clinical practice due to long scan time. We aimed to evaluate the accuracy of a prototype radial turbo-spin-echo (rTSE) sequence, optimized for multi-slice T2 mapping in the abdomen during one breath-hold at 3 T. Methods A multi-sample (fat: 0–35%) agarose phantom doped with MnCl2 and 80 subjects (73 patients undergoing abdomen MR examination and 7 healthy volunteers) were investigated. A radial turbo-spin-echo (rTSE) sequence with and without fat suppression, a Cartesian turbo-spin-echo (Cart-TSE) sequence, and a single-voxel multi-echo STEAM spectroscopy (HISTO) were performed in phantom, and fat-suppressed rTSE and HISTO sequences were performed in in vivo measurements. Two approaches were used to sample T2 values: manually selected circular ROIs and whole liver analysis with Gaussian mixture models (GMM). Results The rTSE-T2s values exhibited a strong correlation with Cart-TSE-T2s (R2 = 0.988) and with HISTO-T2s of water (R2 = 0.972) in phantom with an offset between rTSE and Cart-TSE maps (mean difference = 3.17 ± 1.18 ms). The application of fat suppression decreased T2 values, and the effect was directly proportional to the amount of fat. Measurements in patients yielded a linear relationship between rTSE- and HISTO-T2s (R2 = 0.546 and R2 = 0.580 for ROI and GMM, respectively). Conclusion The fat-suppressed rTSE sequence allows for fast and accurate determination of T2 values of the liver, and appears to be suitable for further large cohort studies. Key Points •Radial turbo-spin-echo T2 mapping performs comparably to Cartesian TSE-T2 mapping, but an offset in values is observed in phantom measurements. •Fat-suppressed radial turbo-spin-echo T2 mapping is consistent with T2 of water as assessed by MRS in phantom measurements. •Fat-suppressed radial turbo-spin-echo sequence allows fast T2 mapping of the liver in a single breath-hold and is correlated with MRS-based T2 of water.


2001 ◽  
Vol 115 (1) ◽  
pp. 14-21 ◽  
Author(s):  
D. J. Annesley-Williams ◽  
R. D. Laitt ◽  
J. P. R. Jenkins ◽  
R. T. Ramsden ◽  
J. E. Gillespie

High resolution T2-weighted magnetic resonance (MR) imaging has been proposed as a rapid, inexpensive means of investigating patients with sensorineural deafness, particularly to exclude vestibular schwannomas. Whether the accepted ‘gold standard’ of contrast-enhanced T1-weighted images can be omitted, however, remains controversial. Over a 22-month period the use of axial turbo-spin echo T2-weighted images (T2W) were prospectively compared with contrast-enhanced T1-weighted spin echo scans in the evaluation of 513 patients presenting with audiovestibular symptoms. A 2-D T2W turbo spin echo (TSE) sequence with 3 mm slices was used in 340 patients while a 3-D sequence with overlapping 1 mm slices was used in 173 patients. The T2-weighted image findings were documented and subsequently compared with contrast-enhanced images. With the 2-D sequence 24 patients (25 lesions) had internal auditory meatus (IAM)/cerebello-pontine angle (CPA) masses identified by contrast-enhanced T1-weighted images, all of which were seen on the T2-weighted TSE sequence; there was one false positive ‘mass’ on the T2-weighted scans and one false negative case of IAM dural enhancement on T1-weighted imaging; six were considered normal initially on the T2-weighted images although three were subtly abnormal in retrospect. With the 3-D sequence three acoustic neuromas were all identified correctly with no false positive and only one false negative result (labyrinthitis). The 2-D and 3-D images were judged technically inadequate for clinical assessment in 15 and nine per cent respectively. We conclude that mass lesions of the IAM/CPA can be reliably identified on T2W TSE imaging but labyrinthine lesions may be missed without contrast enhancement. This is of particular importance in planning the management of neurofibromatosis type 2. Non-neoplastic disorders of the inner ear are also likely to be missed.


Radiology ◽  
2019 ◽  
Vol 293 (3) ◽  
pp. 620-630 ◽  
Author(s):  
Marion Roux ◽  
Tom Hilbert ◽  
Mahmoud Hussami ◽  
Fabio Becce ◽  
Tobias Kober ◽  
...  

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