Evaluation of a single-breath-hold radial turbo-spin-echo sequence for T2 mapping of the liver at 3T

Abstract Objectives T2 mapping of the liver is a potential diagnostic tool, but conventional techniques are difficult to perform in clinical practice due to long scan time. We aimed to evaluate the accuracy of a prototype radial turbo-spin-echo (rTSE) sequence, optimized for multi-slice T2 mapping in the abdomen during one breath-hold at 3 T. Methods A multi-sample (fat: 0–35%) agarose phantom doped with MnCl2 and 80 subjects (73 patients undergoing abdomen MR examination and 7 healthy volunteers) were investigated. A radial turbo-spin-echo (rTSE) sequence with and without fat suppression, a Cartesian turbo-spin-echo (Cart-TSE) sequence, and a single-voxel multi-echo STEAM spectroscopy (HISTO) were performed in phantom, and fat-suppressed rTSE and HISTO sequences were performed in in vivo measurements. Two approaches were used to sample T2 values: manually selected circular ROIs and whole liver analysis with Gaussian mixture models (GMM). Results The rTSE-T2s values exhibited a strong correlation with Cart-TSE-T2s (R2 = 0.988) and with HISTO-T2s of water (R2 = 0.972) in phantom with an offset between rTSE and Cart-TSE maps (mean difference = 3.17 ± 1.18 ms). The application of fat suppression decreased T2 values, and the effect was directly proportional to the amount of fat. Measurements in patients yielded a linear relationship between rTSE- and HISTO-T2s (R2 = 0.546 and R2 = 0.580 for ROI and GMM, respectively). Conclusion The fat-suppressed rTSE sequence allows for fast and accurate determination of T2 values of the liver, and appears to be suitable for further large cohort studies. Key Points •Radial turbo-spin-echo T2 mapping performs comparably to Cartesian TSE-T2 mapping, but an offset in values is observed in phantom measurements. •Fat-suppressed radial turbo-spin-echo T2 mapping is consistent with T2 of water as assessed by MRS in phantom measurements. •Fat-suppressed radial turbo-spin-echo sequence allows fast T2 mapping of the liver in a single breath-hold and is correlated with MRS-based T2 of water.

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Reproducibility of left ventricular mass measurement using a half-Fourier black-blood single-shot fast spin-echo sequence within a single breath hold: Comparison with a conventional multiple breath-hold segmented gradient echo technique in patients

Journal of Magnetic Resonance Imaging ◽

10.1002/jmri.10006 ◽

2002 ◽

Vol 15 (6) ◽

pp. 654-660 ◽

Cited By ~ 8

Author(s):

Olivier Vignaux ◽

Denis Duboc ◽

Joel Coste ◽

Christophe Argaud ◽

Pierre Carlier ◽

...

Keyword(s):

Mass Measurement ◽

Spin Echo ◽

Left Ventricular ◽

Fast Spin Echo ◽

Breath Hold ◽

Black Blood ◽

Single Shot ◽

Single Breath ◽

Single Breath Hold ◽

Spin Echo Sequence

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Free-breathing BLADE acquisition method improves T2-weighted cardiac MR image quality compared with conventional breath-hold turbo spin-echo cartesian acquisition

Acta Radiologica ◽

10.1177/0284185120924567 ◽

2020 ◽

pp. 028418512092456

Author(s):

Jingjing Liu ◽

Hang Jin ◽

Yinyin Chen ◽

Caixia Fu ◽

Caizhong Chen ◽

...

Keyword(s):

Image Quality ◽

Spin Echo ◽

Free Breathing ◽

Fat Suppression ◽

Breath Hold ◽

Signal Loss ◽

Turbo Spin Echo ◽

Turbo Spin ◽

Imaging Sequence ◽

Ghosting Artifacts

Background Cardiac magnetic resonance (MR) has become an essential diagnostic imaging modality in cardiovascular disease. However, the insufficient image quality of traditional breath-hold (BH) T2-weighted (T2W) imaging may compromise its diagnostic accuracy. Purpose To assess the efficacy of the BLADE technique to reduce motion artifacts and improve the image quality. Material and Methods Free-breathing TSE-T2W imaging sequence with cartesian and BLADE k-space trajectory were acquired in 20 patients. Thirty patients underwent conventional BH turbo spin-echo (TSE) T2W imaging and free-breathing BLADE T2W (FB BLADE-T2W) imaging. Twenty-one patients who had a signal loss of myocardium in BH short-axis T2W turbo inversion recovery (TSE-T2W-TIR) were scanned using free-breathing BLADE T2W turbo inversion recovery (BLADE TSE-T2W-TIR). The overall image quality, blood nulling, and visualization of the heart were scored on a 5-point Likert scale. The signal loss of myocardium, incomplete fat suppression near the myocardium, and the streaking or ghosting artifacts were noted in T2W-TIR sequences additionally. Results The overall imaging quality, blood nulling, and the visualization of heart structure of FB BLADE-T2W imaging sequence were significantly better than those of FB T2W imaging with Cartesian k-space trajectory and BH TSE-T2W imaging sequence ( P<0.01). The FB BLADE TSE-T2W-TIR reduces the myocardium signal dropout ( P<0.05), incomplete fat suppression near myocardium ( P<0.05), and the streaking and ghosting artifacts ( P<0.05) in comparison with the BH TSE-T2W-TIR. Conclusions FB BLADE T2W imaging provides improved myocardial visibility, less motion sensitivity, and better image quality. It may be applied in patients who have poor breath-holding capability.

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