Electrooxidation behavior of warfarin in Fe3O4 nanoparticles modified carbon paste electrode and its determination in real samples

2015 ◽  
Vol 48 ◽  
pp. 235-242 ◽  
Author(s):  
Mohammad Bagher Gholivand ◽  
Maryam Torkashvand ◽  
Eilnaz yavari
Author(s):  
Ali Afruz ◽  
Mandana Amiri ◽  
Hamideh Imanzadeh

Abstract Here, we developed a sensitive electrochemical sensor for famotidine (FAT) using Cu2O nanoparticles and reduced graphene oxide (rGO) as a sensing platform. The Cu2O nanoparticles and rGO were synthesized through a simple process and characterized by versatile analytical methods. The prepared Cu2O nanoparticles and rGO were taken to modify the carbon paste electrode (Cu2O/rGO/CPE) and developed for the electrochemical analysis of the FAT at pH 6.0. Cu2O/rGO/CPE showed superior electrocatalytic activity for detecting FAT, attributed to the high surface area of rGO and the electrocatalytic properties of Cu2O nanoparticles. The designed FAT sensor exhibited two linear ranges from 0.1-3 µM and 3-50 µM with a detection limit of 0.08 µM (S/N=3) using a differential pulse voltammetry. The proposed sensor also showed a repeatable and stable response over one month with negligible interference from usual organic and inorganic species. The sensor was also validated measuring FAT in real samples (urine, serum and pharmaceutical tablet) with good recovery values from 99.6 to 110.9%.


2018 ◽  
Vol 30 (8) ◽  
pp. 1855-1864 ◽  
Author(s):  
Fatima Ezzahra Salih ◽  
Larbi Oularbi ◽  
El Halim ◽  
Miloud Elbasri ◽  
Aicha Ouarzane ◽  
...  

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