Transport and lymphatic uptake of monoclonal antibodies after subcutaneous injection

2021 ◽  
pp. 104228
Author(s):  
Ehsan Rahimi ◽  
Soroush Aramideh ◽  
Dingding Han ◽  
Hector Gomez ◽  
Arezoo M. Ardekani
Keyword(s):  
Monoclonal Antibodies ◽  
Subcutaneous Injection ◽  
Lymphatic Uptake

scholarly journals Lymphatic uptake and biodistribution of liposomes after subcutaneous injection

1998 ◽  
Vol 1370 (2) ◽  
pp. 259-272 ◽  
Author(s):  
C Oussoren ◽  
M Velinova ◽  
G Scherphof ◽  
J.J van der Want ◽  
N van Rooijen ◽  
...  
Keyword(s):  
Subcutaneous Injection ◽  
Lymphatic Uptake

Isogeometric analysis of subcutaneous injection of monoclonal antibodies

2021 ◽  
Vol 373 ◽  
pp. 113550
Author(s):  
Mario de Lucio ◽  
Miguel Bures ◽  
Arezoo M. Ardekani ◽  
Pavlos P. Vlachos ◽  
Hector Gomez
Keyword(s):  
Monoclonal Antibodies ◽  
Isogeometric Analysis ◽  
Subcutaneous Injection

Fate of Multimeric Oligomers, Submicron, and Micron Size Aggregates of Monoclonal Antibodies Upon Subcutaneous Injection in Mice

2016 ◽  
Vol 105 (5) ◽  
pp. 1693-1704 ◽  
Author(s):  
Grzegorz Kijanka ◽  
Jared S. Bee ◽  
Steven M. Bishop ◽  
Ivo Que ◽  
Clemens Löwik ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Subcutaneous Injection ◽  
Micron Size

Transport and lymphatic uptake of biotherapeutics through subcutaneous injection

2021 ◽  
Author(s):  
Dingding Han ◽  
Soroush Aramideh ◽  
Ehsan Rahimi ◽  
Arezoo M. Ardekani
Keyword(s):  
Subcutaneous Injection ◽  
Lymphatic Uptake

scholarly journals Lymphatic uptake and biodistribution of liposomes after subcutaneous injection.

1997 ◽  
Vol 1328 (2) ◽  
pp. 261-272 ◽  
Author(s):  
C. Oussoren ◽  
J. Zuidema ◽  
D.J.A. Crommelin ◽  
G. Storm
Keyword(s):  
Subcutaneous Injection ◽  
Lymphatic Uptake

Ultrastructural analysis of unique glycoconjugates in the rat olfactory system

1992 ◽  
Vol 50 (1) ◽  
pp. 890-891
Author(s):  
James E. Crandall ◽  
Linda C. Hassinger ◽  
Gerald A. Schwarting
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Monoclonal Antibodies ◽  
Olfactory System ◽  
Olfactory Bulbs ◽  
Temporal And Spatial Patterns ◽  
Carbohydrate Epitopes ◽  
Olfactory Systems ◽  
Temporal And Spatial ◽  
Cell Surface Glycoconjugates

Cell surface glycoconjugates are considered to play important roles in cell-cell interactions in the developing central nervous system. We have previously described a group of monoclonal antibodies that recognize defined carbohydrate epitopes and reveal unique temporal and spatial patterns of immunoreactivity in the developing main and accessory olfactory systems in rats. Antibody CC2 reacts with complex α-galactosyl and α-fucosyl glycoproteins and glycolipids. Antibody CC1 reacts with terminal N-acetyl galactosamine residues of globoside-like glycolipids. Antibody 1B2 reacts with β-galactosyl glycolipids and glycoproteins. Our light microscopic data suggest that these antigens may be located on the surfaces of axons of the vomeronasal and olfactory nerves as well as on some of their target neurons in the main and accessory olfactory bulbs.

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