scholarly journals Comparative cellular pharmacokinetics and pharmacodynamics of siRNA delivery by SPANosomes and by cationic liposomes

2013 ◽  
Vol 9 (4) ◽  
pp. 504-513 ◽  
Author(s):  
Chenguang Zhou ◽  
Yue Zhang ◽  
Bo Yu ◽  
Mitch A. Phelps ◽  
L. James Lee ◽  
...  
Keyword(s):  
Sirna Delivery ◽  
Cationic Liposomes ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Cellular Pharmacokinetics

Enhanced survivin siRNA delivery using cationic liposomes containing linoleic acid-modified polyethylenimine

2016 ◽  
Vol 12 (2) ◽  
pp. 503
Author(s):  
Shuang Yang ◽  
Xuewei Yang ◽  
Jing Xie ◽  
Robert J. Lee ◽  
Lesheng Teng
Keyword(s):  
Linoleic Acid ◽  
Sirna Delivery ◽  
Cationic Liposomes

The development of tertiary amine cationic lipids for safe and efficient siRNA delivery

2019 ◽  
Vol 7 (7) ◽  
pp. 2777-2792 ◽  
Author(s):  
Ziming Lin ◽  
Moxyel Bao ◽  
Zexuan Yu ◽  
Lingjing Xue ◽  
Caoyun Ju ◽  
...  
Keyword(s):  
Tertiary Amine ◽  
Sirna Delivery ◽  
Cationic Lipid ◽  
Cationic Liposomes ◽  
Cationic Lipids

Tertiary amine-derived cationic lipid serves as the primary lipid of cationic liposomes, which can balance the effectiveness and safety of siRNA vectors.

scholarly journals New antimalarial 3-methoxy-1,2-dioxanes: optimization of cellular pharmacokinetics and pharmacodynamics properties by incorporation of amino and N-heterocyclic moieties at C4

RSC Advances ◽  
2015 ◽  
Vol 5 (89) ◽  
pp. 72995-73010 ◽  
Author(s):  
D. P. Sonawane ◽  
M. Persico ◽  
Y. Corbett ◽  
G. Chianese ◽  
A. Di Dato ◽  
...  
Keyword(s):  
Antimalarial Activity ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Cellular Pharmacokinetics

A new series of 3-methoxy-1,2-dioxanes containing an amino moiety at C4 was synthesized, displaying nanomolar antimalarial activity without being cytotoxic.

scholarly journals Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0172628 ◽  
Author(s):  
Narasimha M. Midde ◽  
Namita Sinha ◽  
Pradeep B. Lukka ◽  
Bernd Meibohm ◽  
Santosh Kumar
Keyword(s):  
Ethanol Exposure ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Cellular Pharmacokinetics ◽  
Hiv 1

Effect of cationic lipid in cationic liposomes on siRNA delivery into the lung by intravenous injection of cationic lipoplex

2018 ◽  
Vol 27 (2) ◽  
pp. 217-227 ◽  
Author(s):  
Yoshiyuki Hattori ◽  
Mari Nakamura ◽  
Nozomi Takeuchi ◽  
Kyoko Tamaki ◽  
Satono Shimizu ◽  
...  
Keyword(s):  
Intravenous Injection ◽  
Sirna Delivery ◽  
Cationic Lipid ◽  
Cationic Liposomes

Enhanced siRNA delivery using cationic liposomes with new polyarginine-conjugated PEG-lipid

2010 ◽  
Vol 392 (1-2) ◽  
pp. 141-147 ◽  
Author(s):  
Hyun-Ki Kim ◽  
Enkhzaya Davaa ◽  
Chang-Seon Myung ◽  
Jeong-Sook Park
Keyword(s):  
Sirna Delivery ◽  
Cationic Liposomes
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