Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing

Receptor Agonists ◽

Metabotropic Glutamate ◽

Analgesic Effects ◽

Pain Models ◽

Group Ii ◽

Repeated Dosing

Pharmacophore Models of Group I and Group II Metabotropic Glutamate Receptor Agonists. Analysis of Conformational, Steric, and Topological Parameters Affecting Potency and Selectivity

Journal of Medicinal Chemistry ◽

10.1021/jm990182b ◽

1999 ◽

Vol 42 (15) ◽

pp. 2816-2827 ◽

Cited By ~ 21

Author(s):

Gabriele Costantino ◽

Antonio Macchiarulo ◽

Roberto Pellicciari

Keyword(s):

Glutamate Receptor ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Topological Parameters ◽

Group I ◽

Group Ii ◽

Pharmacophore Models

Acute pancreatitis decreases the sensitivity of pancreas-projecting dorsal motor nucleus of the vagus neurones to group II metabotropic glutamate receptor agonists in rats

The Journal of Physiology ◽

10.1113/jphysiol.2013.270108 ◽

2014 ◽

Vol 592 (6) ◽

pp. 1411-1421 ◽

Cited By ~ 4

Author(s):

Tanja Babic ◽

R. Alberto Travagli

Keyword(s):

Acute Pancreatitis ◽

Glutamate Receptor ◽

Motor Nucleus ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Dorsal Motor Nucleus ◽

Group II metabotropic glutamate receptor agonists as a potential drug for schizophrenia

European Journal of Pharmacology ◽

10.1016/j.ejphar.2009.12.041 ◽

2010 ◽

Vol 639 (1-3) ◽

pp. 59-66 ◽

Cited By ~ 41

Author(s):

Shigeyuki Chaki

Keyword(s):

Glutamate Receptor ◽

Potential Drug ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia

Neuropharmacology ◽

10.1016/j.neuropharm.2011.06.007 ◽

2012 ◽

Vol 62 (3) ◽

pp. 1473-1483 ◽

Cited By ~ 66

Author(s):

Matthew J. Fell ◽

David L. McKinzie ◽

James A. Monn ◽

Kjell A. Svensson

Keyword(s):

Glutamate Receptor ◽

Allosteric Modulators ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Novel Treatments ◽

Positive Allosteric Modulators ◽

Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV

European Journal of Pharmacology ◽

10.1016/s0014-2999(98)00526-3 ◽

1998 ◽

Vol 356 (2-3) ◽

pp. 149-157 ◽

Cited By ~ 64

Author(s):

John Kilbride ◽

LingQian Huang ◽

Michael J. Rowan ◽

Roger Anwyl

Keyword(s):

Glutamate Receptor ◽

Inhibitory Action ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Anti-epileptic activity of group II metabotropic glutamate receptor agonists (−)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (−)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795)

Neuropharmacology ◽

10.1016/s0028-3908(01)00044-2 ◽

2001 ◽

Vol 41 (1) ◽

pp. 8-18 ◽

Cited By ~ 43

Author(s):

R.X. Moldrich ◽

M. Jeffrey ◽

A. Talebi ◽

P.M. Beart ◽

A.G. Chapman ◽

...

Keyword(s):

Glutamate Receptor ◽

Epileptic Activity ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Depression of monosynaptic excitation of spinal motoneurons by novel metabotropic glutamate receptor agonists

Neuroscience Research Supplements ◽

10.1016/0921-8696(92)90783-w ◽

1992 ◽

Vol 17 ◽

pp. 84

Author(s):

Michiko Ishida ◽

Tomoko Saitoh ◽

Haruhiko Shinozaki

Keyword(s):

Glutamate Receptor ◽

Spinal Motoneurons ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Monosynaptic Excitation

Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat

Neuropharmacology ◽

10.1016/s0028-3908(99)00257-9 ◽

2000 ◽

Vol 39 (5) ◽

pp. 903-910 ◽

Cited By ~ 33

Author(s):

M Pizzi ◽

M Benarese ◽

F Boroni ◽

F Goffi ◽

A Valerio ◽

...

Keyword(s):

Spinal Cord ◽

Glutamate Receptor ◽

Motor Neurons ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Adult Rat ◽

Glutamate Receptor Agonists

Excitatory Effects of the Puberty-Initiating Peptide Kisspeptin and Group I Metabotropic Glutamate Receptor Agonists Differentiate Two Distinct Subpopulations of Gonadotropin-Releasing Hormone Neurons

Journal of Neuroscience ◽

10.1523/jneurosci.1225-08.2008 ◽

2008 ◽

Vol 28 (32) ◽

pp. 8003-8013 ◽

Cited By ~ 75

Author(s):

I. Dumalska ◽

M. Wu ◽

E. Morozova ◽

R. Liu ◽

A. van den Pol ◽

...

Keyword(s):

Glutamate Receptor ◽

Gonadotropin Releasing Hormone ◽

Releasing Hormone ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Group I ◽

Glutamate Receptor Agonists

Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists

Brain Research ◽

10.1016/s0006-8993(99)01065-3 ◽

1999 ◽

Vol 821 (2) ◽

pp. 539-545 ◽

Cited By ~ 19

Author(s):

Michael P Johnson ◽

Maryjo Chamberlain ◽

Gerard M Kelly

Keyword(s):

Glutamate Receptor ◽

Phosphoinositide Hydrolysis ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Group I ◽

Glutamate Receptor Agonists