scholarly journals Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models

2018 ◽  
Vol 136 ◽  
pp. 251-259 ◽  
Author(s):  
Christian Hölscher
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Models ◽  
Neuroprotective Effects ◽  
Receptor Agonists ◽  
Gip Receptor

The Novel Dual GLP-1/GIP Receptor Agonist DA-CH5 Is Superior to Single GLP-1 Receptor Agonists in the MPTP Model of Parkinson’s Disease

2020 ◽  
Vol 10 (2) ◽  
pp. 523-542 ◽  
Author(s):  
Lingyu Zhang ◽  
Liping Zhang ◽  
Yanwei Li ◽  
Lin Li ◽  
Josefine Ulrikke Melchiorsen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Receptor Agonist ◽  
The Novel ◽  
Receptor Agonists ◽  
Mptp Model ◽  
Gip Receptor

scholarly journals Two novel dual GLP-1/GIP receptor agonists are neuroprotective in the MPTP mouse model of Parkinson's disease

2018 ◽  
Vol 133 ◽  
pp. 385-394 ◽  
Author(s):  
Peng Feng ◽  
Xiangjian Zhang ◽  
Dongfang Li ◽  
Chenhui Ji ◽  
Ziyue Yuan ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Mouse Model ◽  
Receptor Agonists ◽  
Gip Receptor

Cassiae semen, a seed of Cassia obtusifolia, has neuroprotective effects in Parkinson’s disease models

2010 ◽  
Vol 48 (8-9) ◽  
pp. 2037-2044 ◽  
Author(s):  
Mi Sun Ju ◽  
Hyo Geun Kim ◽  
Jin Gyu Choi ◽  
Jong Hoon Ryu ◽  
Jinyoung Hur ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Models ◽  
Cassia Obtusifolia ◽  
Neuroprotective Effects

Neuroprotective effects of nitidine in Parkinson's disease models through inhibiting microglia activation: role of the Jak2–Stat3 pathway

RSC Advances ◽  
2016 ◽  
Vol 6 (75) ◽  
pp. 71328-71337 ◽  
Author(s):  
Bao Wang ◽  
Xing-qin Wang ◽  
Shao-song Yang ◽  
Xi Liu ◽  
Da-yun Feng ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Animal Models ◽  
Microglial Activation ◽  
Microglia Activation ◽  
Disease Models ◽  
Neuroprotective Effects ◽  
Stat3 Pathway ◽  
Behavioural Function

In this work we found that nitidine could significantly suppress microglial activationviathe Jak2–Stat3 pathway and obviously improve behavioural function in Parkinson's disease (PD) animal models, which sheds light on PD treatment.

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