Consequences of removing the flattening filter from linear accelerators in generating high dose rate photon beams for clinical applications: A Monte Carlo study verified by measurement

2007 ◽  
Vol 261 (1-2) ◽  
pp. 755-759 ◽  
Author(s):  
E. Ishmael Parsai ◽  
David Pearson ◽  
Thomas Kvale
Keyword(s):  
Monte Carlo ◽  
Dose Rate ◽  
Monte Carlo Study ◽  
High Dose Rate ◽  
Clinical Applications ◽  
High Dose ◽  
Photon Beams ◽  
Linear Accelerators ◽  
Flattening Filter

scholarly journals Dosimetry of indigenously developed192Ir high-dose rate brachytherapy source: An EGSnrc Monte Carlo study

2016 ◽  
Vol 41 (2) ◽  
pp. 115 ◽  
Author(s):  
Sridhar Sahoo ◽  
TPalani Selvam ◽  
SD Sharma ◽  
Trupti Das ◽  
AC Dey ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Dose Rate ◽  
Monte Carlo Study ◽  
High Dose Rate ◽  
High Dose ◽  
High Dose Rate Brachytherapy ◽  
Brachytherapy Source

scholarly journals Monte Carlo Study of Radiation Dose Enhancement by Gadolinium in Megavoltage and High Dose Rate Radiotherapy

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e109389 ◽  
Author(s):  
Daniel G. Zhang ◽  
Vladimir Feygelman ◽  
Eduardo G. Moros ◽  
Kujtim Latifi ◽  
Geoffrey G. Zhang
Keyword(s):  
Monte Carlo ◽  
Radiation Dose ◽  
Dose Rate ◽  
Monte Carlo Study ◽  
High Dose Rate ◽  
High Dose ◽  
Dose Enhancement

scholarly journals Translational Research in FLASH Radiotherapy—From Radiobiological Mechanisms to In Vivo Results

Biomedicines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 181
Author(s):  
Loredana G. Marcu ◽  
Eva Bezak ◽  
Dylan D. Peukert ◽  
Puthenparampil Wilson
Keyword(s):  
Dose Rate ◽  
High Dose Rate ◽  
Current Status ◽  
Therapeutic Window ◽  
High Dose ◽  
Linear Accelerators ◽  
Radiation Delivery ◽  
Tissue Sparing

FLASH radiotherapy, or the administration of ultra-high dose rate radiotherapy, is a new radiation delivery method that aims to widen the therapeutic window in radiotherapy. Thus far, most in vitro and in vivo results show a real potential of FLASH to offer superior normal tissue sparing compared to conventionally delivered radiation. While there are several postulations behind the differential behaviour among normal and cancer cells under FLASH, the full spectra of radiobiological mechanisms are yet to be clarified. Currently the number of devices delivering FLASH dose rate is few and is mainly limited to experimental and modified linear accelerators. Nevertheless, FLASH research is increasing with new developments in all the main areas: radiobiology, technology and clinical research. This paper presents the current status of FLASH radiotherapy with the aforementioned aspects in mind, but also to highlight the existing challenges and future prospects to overcome them.

scholarly journals Erratum to: Monte Carlo dosimetry of the IRAsource high dose rate 192Ir brachytherapy source

2016 ◽  
Vol 39 (2) ◽  
pp. 591-591 ◽  
Author(s):  
Akbar Sarabiasl ◽  
Navid Ayoobian ◽  
Hossein Poorbaygi ◽  
Iraj Jabbari ◽  
Mohammad Reza Javanshir
Keyword(s):  
Monte Carlo ◽  
Dose Rate ◽  
High Dose Rate ◽  
High Dose ◽  
Brachytherapy Source
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