Trends of steroid therapy for Duchenne muscular dystrophy in Japan

2015 ◽  
Vol 25 ◽  
pp. S199
Author(s):  
F. Takeuchi ◽  
H. Komaki ◽  
H. Nakamura ◽  
N. Yonemoto ◽  
K. Kashiwabara ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy

DUCHENNE MUSCULAR DYSTROPHY AND STEROID THERAPY: EVALUATION OF PATIENTS' MOTOR PERFORMANCE

2006 ◽  
Vol 37 (S 1) ◽  
Author(s):  
SL Parreira ◽  
MBD Resende ◽  
R Cardoso Alves ◽  
MDC Peduto ◽  
MS Carvalho ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy ◽  
Motor Performance ◽  
Therapy Evaluation

T.P.49 Low-dose steroid therapy for cardiomyopathy in Duchenne Muscular Dystrophy patients

2012 ◽  
Vol 22 (9-10) ◽  
pp. 866
Author(s):  
K. Ishigaki ◽  
T. Murakami ◽  
T. Saito ◽  
T. Sato ◽  
S. Kajino ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy ◽  
Low Dose

Vitamin D in the prevention and treatment of comorbid conditions in Duchenne muscular dystrophy

2021 ◽  
Vol 2 (1) ◽  
pp. 38-50
Author(s):  
Tatiana A. Gremiakova ◽  
Vasiliy M. Souslov ◽  
Gulzhan E. Sakbaeva ◽  
Andrey A. Stepanov
Keyword(s):  
Vitamin D ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy ◽  
Motor Development ◽  
Smooth Muscles ◽  
Comorbid Conditions ◽  
Increased Risk ◽  
Positive Effect ◽  
Tubular Bones

Duchenne muscular dystrophy (DMD) is an X-linked recessive degenerative neuromuscular disorder due to a deficiency of dystrophin protein. This protein is most common in skeletal and cardiac muscles, to a lesser extent in smooth muscles and the brain. With DMD, progressive damage and muscle degeneration, a delay in motor development, and respiratory cardiac disorders are progressing. Patients with DMD have an increased risk of developing osteoporosis, fractures of the tubular bones and vertebrae, and neurocognitive impairment. Vitamin D is recommended prophylactically for DMD since many studies have shown its deficiency. The purpose of this work is to consolidate the literature data on the vitamin D deficiency in DMD patients and its effects on the development of concurrent comorbid conditions of the musculoskeletal, endocrine, and nervous systems. The authors discuss data concerning the appropriate level of vitamin D throughout the life span of DMD has a positive effect on the course of the disease patients’ quality of life ends. Primary clinical outcomes of vitamin D normalization include prevention of the development of osteoporosis (especially after the start of steroid therapy), fractures of the tubular bones and vertebrae, prolonged ability to walk, more effective treatment with bisphosphonates, including a decrease in the number of complications during initial use and lower jaw necrosis, positive effect on the expression of autistic spectrum symptoms. For patients with long-term steroid therapy, metabolic and liver disorders, calcidiol could be used, allowing quick deficiency compensation instead of standard vitamin D preparations.

Steroid therapy in duchenne muscular dystrophy (DMD)

1992 ◽  
Vol 8 (5) ◽  
pp. 353
Author(s):  
Alberto L. Dubrovsky ◽  
Lilia Mesa ◽  
José Corderi ◽  
Patricia Marco ◽  
Daniel Flores
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy

Steroid Therapy and Cardiac Function in Duchenne Muscular Dystrophy

2005 ◽  
Vol 26 (6) ◽  
pp. 768-771 ◽  
Author(s):  
L.W. Markham ◽  
R.L. Spicer ◽  
P.R. Khoury ◽  
B.L. Wong ◽  
K.D. Mathews ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cardiac Function ◽  
Steroid Therapy

scholarly journals All-Cause Mortality and Cardiovascular Outcomes With Prophylactic Steroid Therapy in Duchenne Muscular Dystrophy

2013 ◽  
Vol 61 (9) ◽  
pp. 948-954 ◽  
Author(s):  
Gernot Schram ◽  
Anne Fournier ◽  
Hugues Leduc ◽  
Nagib Dahdah ◽  
Johanne Therien ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy ◽  
Cardiovascular Outcomes ◽  
All Cause Mortality

scholarly journals Lung function monitoring in patients with duchenne muscular dystrophy on steroid therapy

2012 ◽  
Vol 5 (1) ◽  
pp. 435 ◽  
Author(s):  
Darlene L Machado ◽  
Elaine C Silva ◽  
Maria B D Resende ◽  
Celso R F Carvalho ◽  
Edmar Zanoteli ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Lung Function ◽  
Steroid Therapy

P4.6 Efficacy of low-dose steroid therapy for scoliosis in patients with Duchenne muscular dystrophy

2011 ◽  
Vol 21 (9-10) ◽  
pp. 706
Author(s):  
T. Murakami ◽  
K. Ishigaki ◽  
T. Saito ◽  
T. Sato ◽  
S. Onai ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Steroid Therapy ◽  
Low Dose
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