Transcellular transport of 4-iodo-L-meta-tyrosine via system L across monolayers of kidney epithelial cell line LLC-PK1

2004 ◽  
Vol 31 (4) ◽  
pp. 477-482 ◽  
Author(s):  
Naoto Shikano ◽  
Keiichi Kawai ◽  
Syuichi Nakajima ◽  
Akiko Kubodera ◽  
Nobuo Kubota ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Line ◽  
Epithelial Cell Line ◽  
Transcellular Transport ◽  
System L ◽  
Kidney Epithelial Cell ◽  
Kidney Epithelial Cell Line

Transcellular transport of radioiodinated 3-iodo-α-methyl-L-tyrosine across monolayers of kidney epithelial cell line LLC-PK1

2004 ◽  
Vol 18 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Naoto Shikano ◽  
Keiichi Kawai ◽  
Syuichi Nakajima ◽  
Akiko Kubodera ◽  
Nobuo Kubota ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Line ◽  
Epithelial Cell Line ◽  
Transcellular Transport ◽  
Kidney Epithelial Cell ◽  
Kidney Epithelial Cell Line

Comparison of the transcellular transport of FDG and D-glucose by the kidney epithelial cell line, LLC-PK1

2010 ◽  
Vol 31 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Masato Kobayashi ◽  
Naoto Shikano ◽  
Ryuichi Nishii ◽  
Yasushi Kiyono ◽  
Hiroyo Araki ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Line ◽  
Epithelial Cell Line ◽  
Transcellular Transport ◽  
Kidney Epithelial Cell ◽  
Kidney Epithelial Cell Line

scholarly journals Interaction of Azole Antifungal Agents with Human P-glycoprotein Expressed in a Kidney Epithelial Cell Line, LLC-PK1.

2001 ◽  
Vol 16 (1) ◽  
pp. 5-11
Author(s):  
Takaaki KODAWARA ◽  
Ikuko YANO ◽  
Satohiro MASUDA ◽  
Tatsuya ITO ◽  
Hiroko WAKASUGI ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Line ◽  
Antifungal Agents ◽  
Epithelial Cell Line ◽  
P Glycoprotein ◽  
Kidney Epithelial Cell ◽  
Kidney Epithelial Cell Line

scholarly journals Synthesis and Cytotoxicity Studies of Titanocene C Analogues

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Megan Hogan ◽  
James Claffey ◽  
Eoin Fitzpatrick ◽  
Thomas Hickey ◽  
Clara Pampillón ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Line ◽  
Epithelial Cell Line ◽  
Pig Kidney ◽  
Cytotoxicity Studies ◽  
Kidney Epithelial Cell ◽  
Kidney Epithelial Cell Line

From the carbolithiation of 6-N,N-dimethylamino fulvene (3) and 2,4[bis(N,N-dimethylamino)methyl]-N-methylpyrrolyl lithium (2a), N-(N′,N′-dimethylaminomethyl)benzimidazolyl lithium (2b)' or p-(N,N-dimethylamino)methylphenyl lithium (2c), the corresponding lithium cyclopentadienide intermediate (4a–c) was formed. These three lithiated intermediates underwent a transmetallation reaction with TiCl4' resulting in N,N-dimethylamino-functionalised titanocenes 5a–c. When these titanocenes were tested against a pig kidney epithelial cell line (LLC-PK), the IC50 values obtained were of 23, and 52 μM for titanocenes 5a and 5b, respectively. The most cytotoxic titanocene in this paper, 5c with an IC50 value of 13 μM, was found to be approximately two times less cytotoxic than its analogue Titanocene C (IC50=5.5 μM) and almost four times less cytotoxic than cisplatin, which showed an IC50 value of 3.3 μM when tested on the LLC-PK cell line.

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