scholarly journals SINONASAL SPINDLE CELL CARCINOMA ARISING FROM INVERTED PAPILLOMA IN A PATIENT WITH HISTORY OF RADIOTHERAPY FOR SINONASAL SQUAMOUS CELL CARCINOMA

Author(s):  
Dr. Faraj Alotaiby ◽  
Dr. Mohammed Islam ◽  
Dr. Indraneel Bhattacharyya ◽  
Dr. Donald Cohen ◽  
Dr. Peter Drew ◽  
...  
2021 ◽  
Vol 5 (3) ◽  
pp. 133-135
Author(s):  
Syeda Asiya Butool ◽  
◽  
Ankit Natani ◽  
Betina Chandolia ◽  
Manas Bajpai ◽  
...  

Abstract Spindle Cell Carcinoma (SpCC) is a biphasic tumor. They are proven to be monoclonal dedifferentiated forms of conventional squamous carcinomas. It is a rare tumor which is infrequently observed in head, neck and in the aerodigestive tract. The tumor is aggressive and shows high frequency of recurrence and metastasis. It is an aggressive variant of squamous cell carcinoma which resembles a true sarcoma. It is a proliferation of spindle cells and squamous cells. For confirmation of diagnosis, immunohistochemistry is used. A Rare case of spindle cell squamous cell carcinoma in a 61 years old male in the tongue.The patient reported of rapidly growing lesion from six months with pain severe pain, dysphagia and difficulty in swallowing patient had history of chewing tobacco from past 35 years. Keywords: Spindle Cell Variant, Biphasic tumor, Head and Neck, Pseudocarcinoma, Sqamous cell, Dysplastic.


Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.


ORL ◽  
2020 ◽  
Vol 82 (6) ◽  
pp. 310-317
Author(s):  
Le Chen ◽  
Qi Chen ◽  
Cai Li ◽  
Liang Zhou ◽  
Shuyi Wang ◽  
...  

<b><i>Aims:</i></b> To investigate the clinical features, treatment, and outcomes of laryngeal spindle cell carcinoma (SpCC). <b><i>Methods:</i></b> Between 2005 and 2014, patients from our hospital with SpCC of the larynx were retrospectively analyzed alongside patient data from the SEER database of America. <b><i>Results:</i></b> A total of 11 patients with SpCC of the larynx were diagnosed and underwent surgery in our hospital. All patients were male and all tumors were located in the glottis. The 3- and 5-year OS rates were both 54.5%. In the SEER database, 148 patients were diagnosed with SpCC of the larynx. The 3- and 5-year OS rates were 72.8 and 63.2%, respectively. According to the comparison of propensity score-matched analysis, the OS was longer in squamous cell carcinoma (SCC) of the larynx (<i>p</i> &#x3c; 0.0001). <b><i>Conclusion:</i></b> SpCC of the larynx is rare and typically originates in the glottis. Its prognosis is worse than that of laryngeal SCC, and surgery is a reasonable treatment strategy.


2005 ◽  
Vol 119 (3) ◽  
pp. 230-232
Author(s):  
Giancarlo Ottaviano ◽  
Gino Marioni ◽  
Rosario Marchese-Ragona ◽  
Filippo Marino ◽  
Alberto Staffieri

Synchronous laryngeal malignancies are extremely uncommon. To the best of our knowledge, only four cases of primary synchronous squamous cell carcinoma (SCC) of the larynx are available in the literature. We report the case of a 52-year-old patient with simultaneous spindle-cell carcinoma and SCC in situ of the larynx. The pathogenesis, treatment and prognosis of this rare occurrence have been discussed.


2020 ◽  
Vol 21 ◽  
Author(s):  
Faraj Alotaiby ◽  
Mohammed N. Islam ◽  
Indraneel Bhattacharyya ◽  
Donald M. Cohen ◽  
Peter A. Drew ◽  
...  

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