Low Intraocular Pressure Resulting from Ciliary Body Detachment in Patients with Myotonic Dystrophy

Ophthalmology ◽  
2011 ◽  
Vol 118 (2) ◽  
pp. 260-264 ◽  
Author(s):  
Nicola Rosa ◽  
Michele Lanza ◽  
Maria Borrelli ◽  
Maddalena De Bernardo ◽  
Alberto Palladino ◽  
...  
2008 ◽  
Vol 24 (6) ◽  
pp. 633-638 ◽  
Author(s):  
George D. Kymionis ◽  
Spyridon Charisis ◽  
Vasilios F Diakonis ◽  
Aristofanis I Pallikaris ◽  
Sonia H. Yoo ◽  
...  

Author(s):  
Sara Jouzdani ◽  
Rouzbeh Amini ◽  
Victor H. Barocas

The aqueous humor (AH) provides oxygen and nutrients for the avascular ocular tissue specifically, the cornea and lens. AH is secreted by the ciliary body into the posterior chamber, passes through pupil, and drains into the anterior chamber (Fig. 1a). Resistance to the aqueous outflow generates the intraocular pressure (IOP), which is 15–20 mmHg in the normal eyes.


2009 ◽  
Vol 50 (5) ◽  
pp. 2185 ◽  
Author(s):  
Mo´nica R. Calera ◽  
Zhao Wang ◽  
Roberto Sanchez-Olea ◽  
David L. Paul ◽  
Mortimer M. Civan ◽  
...  

Cells ◽  
2018 ◽  
Vol 7 (11) ◽  
pp. 210 ◽  
Author(s):  
Ibrahim González-Marrero ◽  
Luis Hernández-Abad ◽  
Emilia Carmona-Calero ◽  
Leandro Castañeyra-Ruiz ◽  
José Abreu-Reyes ◽  
...  

Aquaporin 1 (AQP1) and aquaporin 4 (AQP4) have been identified in the eye as playing an essential role in the formation of the aqueous humor along with the Na+/K+ ATPase pump. Different authors have described the relationship between blood pressure, aqueous humor production, and intraocular pressure with different conclusions, with some authors supporting a positive correlation between blood pressure and intraocular pressure while others disagree. The aim of this work was to study the effect of high blood pressure on the proteins involved in the production of aqueous humor in the ciliary body (CB) and iris. For this purpose, we used the eyes of spontaneously hypertensive rats (SHR) and their control Wistar-Kyoto rats (WKY). Immunofluorescence was performed in different eye structures to analyze the effects of hypertension in the expression of AQP1, AQP4, and the Na+/K+ ATPase α1 and α2 subunits. The results showed an increase in AQP1 and Na+/K+ ATPase α1 and a decrease in AQP4 and Na+/K+ ATPase α2 in the CB of SHR, while an increase in AQP4 and no significant differences in AQP1 were found in the iris. Therefore, systemic hypertension produced changes in the proteins implicated in the movement of water in the CB and iris that could influence the production rate of aqueous humor, which would be affected depending on the duration of systemic hypertension.


2021 ◽  
pp. 83-91
Author(s):  
Takashi Kudo ◽  
Yukihiko Suzuki ◽  
Kodai Yamauchi ◽  
Toshio Tando ◽  
Kobu Adachi ◽  
...  

We report a case of cyclodialysis with decreased visual acuity after microhook trabeculotomy (mTLO) successfully treated by vitreous surgery. A 41-year-old man had been medically treated for primary open-angle glaucoma in both eyes. He was scheduled to undergo mTLO due to progression of visual field impairment and unstable intraocular pressure in his right eye. His preoperative best-corrected visual acuity (BCVA) was 0.4 OD, and the intraocular pressure was unstable, ranging from 12 to 27 mm Hg. On the day after the operation, a shallow anterior chamber developed, and a low intraocular pressure occurred. His visual acuity continued to decrease, and cyclodialysis was confirmed by ultrasonic biomicroscopy. No improvement was obtained with medical treatment, and his BCVA dropped to 0.08 OD, while his intraocular pressure remained at 2–3 mm Hg. Three months later, a second surgery was performed by combining cataract surgery with intraocular lens implantation, vitrectomy, cryopexy for the pars plana of the ciliary body, and 20% SF6 gas tamponade. Two weeks after the reoperation, the intraocular pressure had been normalized to 12 mm Hg, and the BCVA had returned to 0.3. We successfully treated cyclodialysis as a complication after mTLO by vitreous surgery that led to the recovery of the visual acuity and intraocular pressure.


Author(s):  
Shabab Akbar ◽  
Sapna Ratan Shah

The effects of Prostaglandin Analogs on intraocular pressure and increased aqueous outflow via trabecular meshwork into the schlemm’s canal has been studied in this present research paper. Aqueous humor is an outflow, which flows at the back of the iris in the posterior chamber all the way through the pupil aperture, out into the anterior chamber, and drain from the eye via drainage slope. The eye keeps on making aqueous humor in the ciliary body and it passes through the trabecular meshwork into the scheme of the canal, the key drainage from the eye and it finally goes to the “collector channels” and due to the less amount of aqueous humor fluid flow from the drainage angle, the pressure in the eye starts to increase. For this study, the canal of Schlemm is assumed as a permeable channel. And it is connected by trabecular meshwork. The inner layer of the canal's wall has been assumed as permeable. And the aqueous humor drains into the canal through this porous tissue wall. The objective of this paper is to discuss the effect of prostaglandin analogs on intraocular pressure as the Prostaglandin Analogs work by increasing the outflow of aqueous from the eye.


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