Concurrent infection of intestinal parasites and Helicobacter pylori among school-age children in Central Ethiopia

Abstract Background: Comprehensive nationwide on prevalence, geographic distribution of different species and time trends of soil-transmitted helminths (STHs) are lacking. Therefore, the aim of this study was to provide a summary and location of the available data on STHs infection among preschool and school-age children in Ethiopia. Methods: The search were carried out in Medline via PubMed, Scopus, Science Direct, Web of Science and Google Scholar on data published between 1995 to Fabruary 2020 for studies describing rate of STHs infection among preschool and school-age in Ethiopian. We followed Patient, intervention, Comparsion and Outcome (PICO) approach to identify the studies. Endnote citation manager software version X9 for Windows was utilized to collect and organize search outcomes (into relevant and irrelevant studies) and for removal duplicate articles . We conducted meta-regression to understand the trends and the source of heterogeneity and pooled the prevalence using ‘metaprop’ command using STATA software version 14.Results: A total of 29,311 of the 61,690 children examined during the period under review were infected with one or more species of intestinal parasites yielding an overall prevalence of 48 % (95%CI: 43-53%). The overall pooled estimate of STHs was 33% (95% CI: 28-38%). The prevalence was 44% (95%CI : 31% - 58%) in SNNPR, 34%((95%CI : 28% - 41%) in Amhara region, 31% (95%CI : 19% - 43%) in Oromia region and 10% (95%CI : 7% - 12%) in Tigray region. Soil-transmitted helminths infection rate has been decreasing from 44% (95% CI:30-57%) pre-Mass Drug Administration (MDA) era (1997-2012) to 30% (95% CI:25-34%) post-MDA (2013-2020), although statistically not significant (p = 0.45). A. lumbricoides was the predominant species with a prevalence of 17%. Conclusion: Southern Nations Nationalities and Peoples Region , Amhara and Oromia regions carry the highest burden and are categorized to Moderate Risk Zones (MRZ) and therefore, requiring mass drug administration (MDA) once annually with Albendazole or Mebendazole. Prevalence of SHTs decreased after MDA compared to before MDA, but the decline was not statistically significant. A. lumbricoides was the predominant species of STHs among preschool and school-age children in Ethiopia.

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Intestinal parasitic infections and determinant factors among school age children in Ethiopia: a cross-sectional study

10.21203/rs.2.13354/v2 ◽

2019 ◽

Author(s):

Awrajaw Dessie ◽

Tesfay Gebregzabher ◽

Berihu Kiros ◽

Sintayehu Daba Wami ◽

Daniel Haile Chercos

Keyword(s):

Intestinal Parasites ◽

Cross Sectional Study ◽

School Age Children ◽

Parasitic Infections ◽

Northern Ethiopia ◽

School Age ◽

Cross Sectional ◽

Intestinal Parasitic Infections ◽

Determinant Factors ◽

Finger Nail

Abstract [EXSCINDED] Abstract Abstract Abstract Abstract Abstract Abstract Abstract Objective The aim of this study was to determine the prevalence of intestinal parasitic infections and associated factors among school children in Sebeya primary school, Northern Ethiopia, 2017.Results The prevalence of intestinal parasites in school age children was (29.9%). E.histolytica/dispar 62 (49.21%), G.lamblia 28 (22.22%), and A. lumbricoides 23 (18.25%) were the most prevalent parasitic organisms identified. Unclean finger nail (AOR= 1.72), defecating in the open field (AOR=2.82), and being barefooted (AOR=1.72) were the determinant factors for intestinal parasitic infections. Frequently washing hands reduced the chance of infections by 68%. Furthermore, children in grade 1-4 and 5-6 had higher odds developing the infections than those in grade 7-8 (AOR=8.21 and AOR=2.50, respectively).

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Epidemiology of intestinal parasitic infections in Ethiopian children: A systematic review and meta-analysis

10.21203/rs.2.15732/v1 ◽

2019 ◽

Author(s):

Zeleke Mekonnen ◽

Yonas Alemu ◽

Daniel Emana ◽

Legese Chelkeba

Keyword(s):

Web Of Science ◽

Intestinal Parasites ◽

Meta Analysis ◽

School Age Children ◽

Parasitic Infections ◽

School Age ◽

Policy Makers ◽

Intestinal Parasitic Infections ◽

Pooled Prevalence ◽

Males And Females

Abstract Background : Numerous studies have been carried out on assessing the prevalence of intestinal parasites infections (IPIs) among preschool and school age children in Ethiopia, however, there was no study to gather and systematically analyze this information for policy makers. Methods : We searched Medline via PubMed, Scopus, Science Direct, Web of Science (ISI), and Google Scholar and local peer-reviewed journals published from inception to 2019 for studies describing prevalence of IPIs among preschool and school age children. We conducted meta-regression to understand the trend and the source of heterogeneity and pooled the prevalence using ‘metaprop’ command using STATA software (Intercooled, version 14, STATA Corp, College Station, TX). Results : Eighty three (83) studies examining 56,786 fecal specimens were included. The prevalence of IPIs was 48 %( 95%CI: 42% to 53%) and showed a gradual, but significantly decreasing trends 17% (95% CI: 2.5% to 32%) for each consecutive 6 years) and was similar in males and females. The pooled prevalence in years 1997–2002, 2003–2008, 2009–2014 and >2014 was 71% (95% CI: 57% to 86%), 42% (95% CI: 27% to 56%), 48% (95% CI: 40% to 56%) and 42% (95% CI: 34% to 49%), respectively. Poly-parasitism was observed in 16% (95% CI: 13% to 19 %,) of children while, single parasite infection was observed in 36 %( 95% CI: 30% to 41%). Conclusion: IPIs are highly prevalent and well distributed across the regional states of Ethiopia. Southern and Amhara regional states carry the highest burden. We observed a gradual, but significant decreasing trends in prevalence of IPIs among Ethiopian children over the last two decades.

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Intestinal parasitic infections and determinant factors among school age children in Ethiopia: a cross-sectional study

10.21203/rs.2.13354/v1 ◽

2019 ◽

Author(s):

Awrajaw Dessie ◽

Tesfay Gebregzabher ◽

Berihu Kiros ◽

Sintayehu Daba Wami ◽

Daniel Haile Chercos

Keyword(s):

Intestinal Parasites ◽

Cross Sectional Study ◽

School Age Children ◽

Parasitic Infections ◽

Northern Ethiopia ◽

School Age ◽

Cross Sectional ◽

Intestinal Parasitic Infections ◽

Determinant Factors ◽

Finger Nail

Abstract [EXSCINDED] Objective The aim of this study was to determine the prevalence of intestinal parasitic infections and associated factors among school children in Sobeya primary school, Northern Ethiopia, 2017.Results The prevalence of intestinal parasites in school age children was (29.9%). E.histolytica/dispar 62 (49.21%), G.lamblia 28 (22.22%), and A. lumbricoides 23 (18.25%) were the most prevalent parasitic organisms identified. Unclean finger nail (AOR= 1.72), defecating in the open field (AOR=2.82), and being barefooted (AOR=1.72) were the determinant factors for intestinal parasitic infections. Frequently washing hands reduced the chance of infections by 68%. Furthermore, children in grade 1-4 and 5-6 had higher odds developing the infections than those in grade 7-8 (AOR=8.21 and AOR=2.50, respectively).

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Epidemiology of intestinal parasitic infections in Ethiopian children: A systematic review and meta-analysis

10.21203/rs.2.15732/v3 ◽

2020 ◽

Author(s):

Legese Chelkeba ◽

Zeleke Mekonnen ◽

Yonas Alemu ◽

Daniel Emana

Keyword(s):

Systematic Review ◽

Geographical Distribution ◽

Intestinal Parasites ◽

Meta Analysis ◽

School Age Children ◽

Parasitic Infections ◽

School Age ◽

Pooled Prevalence ◽

Parasite Infections ◽

Risk Areas

Abstract Background : Numerous studies have been carried out on assessing the prevalence of intestinal parasites infections (IPIs) among preschool and school-age children in Ethiopia, but there is lack of study systematically gathered and analyzedinformation for policymakers. Therefore, the aim of this systematic review and meta-analysis was to provide a summary on prevalence, geographical distribution and trends of IPIs among preschool and school-age childrenin Ethiopia. Methods :The search were carried out in Medline via PubMed, Scopus, Science Direct, Web of Science, and Google Scholar from 1996to July2019 for studies describing prevalence of IPIs among preschooland school-age children. We conducted meta-regression to understand the trends and the source of heterogeneity and pooled the prevalence using ‘metaprop’ command using STATA software version 14. Results : Eighty-three(83) studies examining 56,786 fecal specimens were included. The prevalence of IPIs was 48 %( 95%CI: 42% to 53%) and showedsignificantly decreasing trends 17% (95% CI: 2.5% to 32%) for each consecutive 6 years) and was similar in males and females. The pooled prevalence in years 1997–2002, 2003–2008, 2009–2014 and >2014 was 71% (95% CI: 57% to 86%), 42% (95% CI: 27% to 56%), 48% (95% CI: 40% to 56%) and 42% (95% CI: 34% to 49%), respectively. Poly-parasitism was observed in 16% (95% CI: 13% to 19 %,) of the cases. Conclusion: Intestinal parasite infections are highly prevalent among preschool and school-age children and well distributed across the regional states of Ethiopia. Southern and Amhara regional states carry the highest burden.We observed significant decreasing trends in prevalence of IPIs among preschool and school-age Ethiopian children over the last two decades.Therefore, this study is important to locate the geographical distribution and identified high risk areas that should be prioritized further interventions, which complement global efforts towards elimination of IPIs infections by 2020

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1025 Helicobacter pylori Colonization, Respiratory Outcomes and Eczema in School-Age Children: The Generation R Study

Gastroenterology ◽

10.1016/s0016-5085(14)60644-2 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-181-S-182

Author(s):

Wouter J. den Hollander ◽

Agnes M.M. Sonnenschein-van der Voort ◽

Ingrid L. Holster ◽

Johan C. de Jongste ◽

Vincent W. Jaddoe ◽

...

Keyword(s):

Helicobacter Pylori ◽

School Age Children ◽

School Age ◽

Respiratory Outcomes

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Poverty, Dietary Intake, Intestinal Parasites, and Nutritional Status among School-Age Children in the Rural Philippines

Tropical Medicine and Infectious Disease ◽

10.3390/tropicalmed2040049 ◽

2017 ◽

Vol 2 (4) ◽

pp. 49 ◽

Cited By ~ 4

Author(s):

Allen Ross ◽

Keren Papier ◽

Ruby Luceres-Catubig ◽

Thao Chau ◽

Marianette Inobaya ◽

...

Keyword(s):

Nutritional Status ◽

Dietary Intake ◽

Intestinal Parasites ◽

School Age Children ◽

School Age

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Intestinal parasitic infections and determinant factors among school age children in Ethiopia: a cross-sectional study

10.21203/rs.2.13354/v3 ◽

2019 ◽

Author(s):

Awrajaw Dessie ◽

Tesfay Gebregzabher ◽

Berihu Kiros ◽

Sintayehu Daba Wami ◽

Daniel Haile Chercos

Keyword(s):

Intestinal Parasites ◽

Cross Sectional Study ◽

School Age Children ◽

Parasitic Infections ◽

Northern Ethiopia ◽

School Age ◽

Cross Sectional ◽

Intestinal Parasitic Infections ◽

Determinant Factors ◽

Finger Nail

Abstract Objective The aim of this study was to determine the prevalence of intestinal parasitic infections and associated factors among school children in Sebeya primary school, Northern Ethiopia, 2017.Results The prevalence of intestinal parasites in school age children was (29.9%). E.histolytica/dispar 62 (49.21%), G.lamblia 28 (22.22%), and A. lumbricoides 23 (18.25%) were the most prevalent parasitic organisms identified. Unclean finger nail (AOR= 1.72), defecating in the open field (AOR=2.82), and being barefooted (AOR=1.72) were the determinant factors for intestinal parasitic infections. Frequently washing hands reduced the chance of infections by 68%. Furthermore, children in grade 1-4 and 5-6 had higher odds developing the infections than those in grade 7-8 (AOR=8.21 and AOR=2.50, respectively).

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