Comparable survival outcome between acquired cystic disease associated renal cell carcinoma and clear cell carcinoma in patients with end-stage renal disease: a multi-institutional central pathology study

Pathology ◽  
2021 ◽  
Author(s):  
Tsunenori Kondo ◽  
Naoto Sassa ◽  
Hiroshi Yamada ◽  
Toshio Takagi ◽  
Junpei Iizuka ◽  
...  
2020 ◽  
pp. 106689692092858
Author(s):  
Magdalena Chrabańska ◽  
Ryszawy Jakub ◽  
Drozdzowska Bogna

The disease entity of acquired cystic disease–associated renal cell carcinoma (ACD-RCC) has been recently incorporated into the international renal tumor classification. We performed a clinicopathologic study of a patient with bilateral and multifocal ACD-RCCs. The patient received long-term hemodialysis in the end-stage renal disease caused by systemic lupus erythematous. First left-sided nephrectomy and after 6 months right-sided nephrectomy was performed. None of the preoperative radiologic examinations revealed lesions suspected of malignancy. All of the 6 tumors were incidentally found on grossing radical nephrectomy specimens. Histologically, tumors consisted of a variety of growth patterns (including papillary and cribriform) of neoplastic cells with granular eosinophilic cytoplasm and intratumoral oxalate crystals. Neoplastic cells were positive for AMACR, CK AE1/AE3, and CD10; focally positive for CK7; and negative for PAX8. Seven months after the first nephrectomy, the patient still receives dialysis. There was no evidence of lymph node or distant metastases.


1988 ◽  
Vol 140 (5 Part 1) ◽  
pp. 938-943 ◽  
Author(s):  
John J. Basile ◽  
David L. McCullough ◽  
Lloyd H. Harrison ◽  
Raymond B. Dyer

2015 ◽  
Vol 39 (7) ◽  
pp. 873-888 ◽  
Author(s):  
Manju Aron ◽  
Elena Chang ◽  
Loren Herrera ◽  
Ondrej Hes ◽  
Michelle S. Hirsch ◽  
...  

2010 ◽  
Vol 105 (5) ◽  
pp. 620-627 ◽  
Author(s):  
Mohammed A.A.M. Nouh ◽  
Naoto Kuroda ◽  
Motoki Yamashita ◽  
Yushi Hayashida ◽  
Toshifumi Yano ◽  
...  

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