ALA-PDT successfully treated Majocchi’s granuloma by directly killing Trichophyton tonsurans and recruiting T lymphocytes

Author(s):  
Lei Shi ◽  
Qianqian Wu ◽  
Jin Yang ◽  
Jingwen Tan ◽  
Hong Yang ◽  
...  
2020 ◽  
Author(s):  
Yun-yan Zheng ◽  
Yue Li ◽  
Ming-yan Chen ◽  
Qian-yun Mei ◽  
Ru-zhi Zhang

Abstract Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi’s granuloma is anthropophilic Trichophyton rubrum, and it is most commonly located on the anterior aspect of the lower limbs in women. Here, we report a case of Majocchi’s granuloma on the forearm, a site that is rarely involved, in a 62-year-old woman who had been bitten by a dog. Histological examination revealed a dense dermal infiltrate composed of lymphoplasmacytic cells and neutrophils, with hyphae in the dermis. The presence of the fungus, Trichophyton tonsurans, was confirmed by mycological examination. Therefore, histological and mycological examination conformed the diagnosis of Majocchi’s granuloma. The patient was treated with local moxibustion and itraconazole, 200 mg/day, for 60 days, which facilitated a complete resolution of the lesions


2017 ◽  
Vol 34 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Marcelo R. Lyra ◽  
Bruna Muniz Álvarez ◽  
Andrea L. Lanziano ◽  
Maria Auxiliadora A. Imbeth ◽  
Adriana M. Sá ◽  
...  

2020 ◽  
Author(s):  
Yun-yan Zheng ◽  
Yue Li ◽  
Ming-yan Chen ◽  
Qian-yun Mei ◽  
Ru-zhi Zhang

Abstract Majocchi’s granuloma is a rare fungal infection of the dermis. The most frequently identified cause of Majocchi’s granuloma is anthropophilic Trichophyton rubrum , and it is frequently seen on the anterior aspect of the legs of women. Here, we report a case of Majocchi’s granuloma on the forearm, a site that is rarely involved, in a 62-year-old woman who had been bitten by a dog. Histological examination revealed hyphae in the dermis with a diffuse dermal infiltrate consisting of lymphoplasmacytic cells and neutrophils. Mycological examination confirmed the presence of the fungus, Trichophyton rubrum. Therefore, the diagnosis of Majocchi’s granuloma was confirmed by histological and mycological examination. The patient was treated with local moxibustion and itraconazole, 200 mg/day, for 60 days, which promoted a complete regression of the lesions.


2020 ◽  
Author(s):  
Yun-yan Zheng ◽  
Yue Li ◽  
Ming-yan Chen ◽  
Qian-yun Mei ◽  
Ru-zhi Zhang

Abstract Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi’s granuloma is anthropophilic Trichophyton rubrum, and it is most commonly located on the anterior aspect of the lower limbs in women. Here, we report a case of Majocchi’s granuloma on the forearm, a site that is rarely involved, in a 62-year-old woman who had been bitten by a dog. Histological examination revealed a dense dermal infiltrate composed of lymphoplasmacytic cells and neutrophils, with hyphae in the dermis. The presence of the fungus, Trichophyton tonsurans, was confirmed by mycological examination and molecular methods. Therefore, histological and mycological examination confirmed the diagnosis of Majocchi’s granuloma. The patient was treated with local moxibustion and itraconazole, 200 mg/day, for 60 days, which facilitated a complete resolution of the lesions.


2000 ◽  
Vol 111 (1) ◽  
pp. 230-238 ◽  
Author(s):  
Mohammad Reza Rezvany ◽  
Mahmood Jeddi-Tehrani ◽  
Hodjattallah Rabbani ◽  
Ulla Ruden ◽  
Lennart Hammarstrom ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A135-A135
Author(s):  
S FIORUCCI ◽  
A MENCARELLI ◽  
B PALAZZETTI ◽  
E DISTRUTTI ◽  
J WALLACE ◽  
...  

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