The dynamicity of light-up aptamers in one-pot in vitro diagnostic assays

The direct modulation of a light-up aptamer that engenders an analyte-specific aptamer-light-up aptamer chimera is readily applicable in any diagnostic assay for a targeted detection.

Coherent Photonic Terahertz Transmitters Compatible with Direct Comb Modulation

We present a novel approach to coherent photonic THz systems supporting complex modulation. The proposed scheme uses a single optical path avoiding the problems of current implementations, which include: phase decorrelation, 3-dB power loss, and polarization and power matching circuits. More importantly, we show that our novel approach is compatible with direct modulation of the output of an optical frequency comb (i.e., not requiring the demultiplexing of two tones from the comb), further simplifying the system and enabling an increase in the transmitted RF power for a fixed average optical power injected into the photodiode (PD).

Modulation Performance Enhancement of Directly Modulated Injection-Locked Semiconductor Lasers Using an Equivalent Electrical Circuit

We propose an equivalent electrical circuit model to evaluate the direct modulation performance of optically injection-locked (OIL) semiconductor lasers. We modeled the equivalent circuit of the OIL laser based on alternating complex envelope representations, simulated it using the Simulation Program with Integrated Circuit Emphasis (SPICE), and analyzed the frequency response of the OIL laser. Although the frequency response of the OIL laser is better than that of a free-running laser, its 3-dB modulation performance is degraded by the relaxation oscillation that occurs during direct modulation of the semiconductor laser. To overcome this limitation and maintain the maximum modulation performance within the entire locking range, we also designed an electrical filter to preprocess the electrical modulation signal and compensate for the non-flat modulation output of the OIL laser. The damping ratio of the directly modulated OIL laser increased by 0.101 (280%) and its settling time decreased by >0.037 (44%) when the electrical compensation circuit was added, exhibiting a flat 3-dB modulation bandwidth of 28.79 GHz.