Molecular and electrophysiological changes in the prefrontal cortex–amygdala–dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned analgesia

2011 ◽  
Vol 104 (5) ◽  
pp. 1075-1081 ◽  
Author(s):  
Ryan K. Butler ◽  
Linda Nilsson-Todd ◽  
Carine Cleren ◽  
Isabelle Léna ◽  
René Garcia ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Persistent Pain ◽  
Periaqueductal Grey ◽  
Conditioned Analgesia ◽  
Pain State

Identification of genes expressed during conditioned fear, persistent pain state and fear-conditioned analgesia

2010 ◽  
Author(s):  
W. M. Olango ◽  
S. M. Geranton ◽  
O. Moriarty ◽  
M. Roche ◽  
S. P. Hunt ◽  
...  
Keyword(s):  
Conditioned Fear ◽  
Persistent Pain ◽  
Conditioned Analgesia ◽  
Pain State

scholarly journals Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis

Pain ◽  
2010 ◽  
Vol 151 (2) ◽  
pp. 394-403 ◽  
Author(s):  
Christina A. Christianson ◽  
Maripat Corr ◽  
Gary S. Firestein ◽  
Anahita Mobargha ◽  
Tony L. Yaksh ◽  
...  
Keyword(s):  
Persistent Pain ◽  
Serum Transfer ◽  
State Present ◽  
Pain State

Chronic Postsurgical Pain

2017 ◽  
Vol 35 (1) ◽  
pp. 91-115 ◽  
Author(s):  
Steven R. Wooden
Keyword(s):  
Nerve Injury ◽  
Surgical Procedures ◽  
Persistent Pain ◽  
Related Factors ◽  
Postsurgical Pain ◽  
Preventative Measures ◽  
Chronic Postsurgical Pain ◽  
High Incidence ◽  
Pain State ◽  
Made In

Chronic postsurgical pain (CPSP) is defined as a persistent pain state that exists more than 2 months postoperatively and cannot be explained by other causes such as recurrence of disease, apparent inflammation, or other nonsurgical related factors. CPSP is a type of persistent pain condition that often complicates recovery from surgical procedures. It is thought to be caused by surgical nerve injury, but the fact that an identifiable nerve injury can be found in only one-third of CPSP patients suggests that the problem may be far more complex than a simple surgically created nerve injury. Certain surgical procedures report a high incidence of CPSP, helping to isolate likely candidates for this problem, but instituting preventative measures and identifying a treatable source of pain continues to be elusive. Some progress has been made in the areas of prevention and treatment.

Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state

2014 ◽  
Vol 39 (3) ◽  
pp. 435-443 ◽  
Author(s):  
Kieran Rea ◽  
Gemma K. Ford ◽  
Weredeselam M. Olango ◽  
Brendan Harhen ◽  
Michelle Roche ◽  
...  
Keyword(s):  
Ventral Hippocampus ◽  
Persistent Pain ◽  
Pain State ◽  
Arachidonoyl Glycerol
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