Classification of the nonlinear dynamics and bifurcation structure of ultrasound contrast agents excited at higher multiples of their resonance frequency

2012 ◽  
Vol 376 (33) ◽  
pp. 2222-2229 ◽  
Author(s):  
Amin Jafari Sojahrood ◽  
Michael C. Kolios
Keyword(s):  
Nonlinear Dynamics ◽  
Contrast Agents ◽  
Resonance Frequency ◽  
Ultrasound Contrast Agents ◽  
Bifurcation Structure ◽  
Ultrasound Contrast

Shell buckling increases the nonlinear dynamics of ultrasound contrast agents at low acoustic pressures.

2009 ◽  
Vol 125 (4) ◽  
pp. 2680-2680
Author(s):  
Marlies Overvelde ◽  
Benjamin Dollet ◽  
Valeria Garbin ◽  
Nico de Jong ◽  
Detlef Lohse ◽  
...  
Keyword(s):  
Nonlinear Dynamics ◽  
Contrast Agents ◽  
Ultrasound Contrast Agents ◽  
Shell Buckling ◽  
Ultrasound Contrast

scholarly journals Influence of the pressure-dependent resonance frequency on the bifurcation structure and backscattered pressure of ultrasound contrast agents: A numerical investigation

2021 ◽  
Author(s):  
Amin Jafari Sojahrood ◽  
Omar Falou ◽  
Robert Earl ◽  
Raffi Karshafian ◽  
Michael C. Kolios
Keyword(s):  
Contrast Agents ◽  
Cross Section ◽  
Expansion Ratio ◽  
Ultrasound Contrast Agents ◽  
Driving Pressure ◽  
Radial Expansion ◽  
Bifurcation Structure ◽  
Saddle Node Bifurcation ◽  
Ultrasound Contrast ◽  
Ultrasound Applications

The bifurcation structure of the oscillations of ultrasound contrast agents (UCAs) was studied as a function of the driving pressure for excitation frequencies that were determined using the UCAs pressure-dependent resonances (fs)(fs). It was shown that when excited by the (fs)(fs), the UCA can undergo a saddle-node bifurcation (SNB) to higher amplitude oscillations. The driving pressure at which the SNB occurs is controllable and depends on the (fs)(fs) magnitude. Utilizing the appropriate (fs)(fs), the scattering cross section of the UCAs can significantly be enhanced (e.g., ∼∼ninefold) while at the same time avoiding potential UCA destruction (by limiting the radial expansion ratio <<2). This offers significant advantages for optimizing UCA-mediated imaging and therapeutic ultrasound applications.

scholarly journals Influence of the pressure-dependent resonance frequency on the bifurcation structure and backscattered pressure of ultrasound contrast agents: A numerical investigation

2021 ◽  
Author(s):  
Amin Jafari Sojahrood ◽  
Omar Falou ◽  
Robert Earl ◽  
Raffi Karshafian ◽  
Michael C. Kolios
Keyword(s):  
Contrast Agents ◽  
Cross Section ◽  
Expansion Ratio ◽  
Ultrasound Contrast Agents ◽  
Driving Pressure ◽  
Radial Expansion ◽  
Bifurcation Structure ◽  
Saddle Node Bifurcation ◽  
Ultrasound Contrast ◽  
Ultrasound Applications

The bifurcation structure of the oscillations of ultrasound contrast agents (UCAs) was studied as a function of the driving pressure for excitation frequencies that were determined using the UCAs pressure-dependent resonances (fs)(fs). It was shown that when excited by the (fs)(fs), the UCA can undergo a saddle-node bifurcation (SNB) to higher amplitude oscillations. The driving pressure at which the SNB occurs is controllable and depends on the (fs)(fs) magnitude. Utilizing the appropriate (fs)(fs), the scattering cross section of the UCAs can significantly be enhanced (e.g., ∼∼ninefold) while at the same time avoiding potential UCA destruction (by limiting the radial expansion ratio <<2). This offers significant advantages for optimizing UCA-mediated imaging and therapeutic ultrasound applications.

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