Poster 362: Nivolumab-Induced Concurrent Guillain-Barre Syndrome and Myasthenia Gravis in a Patient with Metastatic Renal Cell Carcinoma: A Case Report

PM&R ◽  
2017 ◽  
Vol 9 ◽  
pp. S246-S247 ◽  
Author(s):  
Isabel M. Rutzen-Lopez ◽  
Jack B. Fu ◽  
Jose E. Arias-Berrios
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Myasthenia Gravis ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Guillain-Barré Syndrome following Treatment with Sunitinib Malate

2014 ◽  
Vol 2014 ◽  
pp. 1-2 ◽  
Author(s):  
Ziad Kanaan ◽  
Zain Kulairi ◽  
Mirela Titianu ◽  
Sandip Saha ◽  
Sarwan Kumar
Keyword(s):  
Renal Cell Carcinoma ◽  
Side Effects ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Kinase Inhibitor ◽  
Guillain Barre Syndrome ◽  
Sunitinib Malate ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Sunitinib malate (Sutent, SU011248) is an oral multitargeted tyrosine kinase inhibitor (TKI) used for the treatment of metastatic renal cell carcinoma and imatinib (Gleevec)—resistant gastrointestinal stromal tumor (GIST) with few reported side effects including asthenia, myelosuppression, diarrhea, and mucositis. Scarce literature exists regarding the rare but often serious toxicities of sunitinib. Autoimmune and neurological side effects have been linked to sunitinib’s inhibition of VEGF receptors with a corresponding increase in VEGF levels, which is associated with development of different neuropathies. We hereby report an interesting case of Guillain-Barré syndrome in a middle-aged patient with metastatic renal cell carcinoma following sunitinib treatment.

Guillain–Barré syndrome in a patient with renal cell carcinoma following the first course of pazopanib therapy

2017 ◽  
Vol 23 (11) ◽  
pp. 798-799 ◽  
Author(s):  
Hiroaki Koshikawa ◽  
Tomomi Tsukie ◽  
Akira Kurita ◽  
Mikio Fujikura ◽  
Megumi Suzuki ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Guillain-Barre syndrome: a typical paraneoplastic syndrome in a kidney transplant recipient with allograft renal cell carcinoma: a case report and review of the literature

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Izabela Zakrocka ◽  
Iwona Baranowicz-Gąszczyk ◽  
Agnieszka Korolczuk ◽  
Wojciech Załuska
Keyword(s):  
Renal Cell Carcinoma ◽  
Kidney Transplantation ◽  
Cell Carcinoma ◽  
Kidney Transplant ◽  
Renal Cell ◽  
Guillain Barre Syndrome ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Abstract Background Guillain-Barré syndrome (GBS) is an autoimmune polyneuropathy affecting the peripheral nervous system. This neurological disorder has been previously reported in bone marrow transplant recipients but is uncommon after kidney transplantation. Viral infections and calcineurin inhibitors are the main triggers of GBS in renal transplant recipients. Case presentation In this report, we present a case of a 47-year-old male patient 12 years after his second kidney transplantation who developed GBS due to papillary renal cell carcinoma. Infectious and drug-related origins of GBS were excluded. Despite intensive treatment, graftectomy was performed, after which neurological symptoms resolved. Conclusions In kidney transplant recipients, paraneoplastic aetiology should be considered in the differential diagnosis of GBS.

scholarly journals A case report of nivolumab-induced myasthenia gravis and myositis in a metastatic renal cell carcinoma patient

2020 ◽  
Vol 29 ◽  
pp. 101105 ◽  
Author(s):  
Shotaro Nakanishi ◽  
Sho Nishida ◽  
Minoru Miyazato ◽  
Masato Goya ◽  
Seiichi Saito
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Myasthenia Gravis ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Renal Cell Carcinoma Patient ◽  
Carcinoma Patient

P-PN018. The co-occurrence of myasthenia gravis and Guillain-Barré Syndrome: A case report

2021 ◽  
Vol 132 (8) ◽  
pp. e111
Author(s):  
R. Freshimona ◽  
A. Wijaya ◽  
Aryatama ◽  
S. Djojoatmodjo ◽  
J. Liman ◽  
...  
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Immune-related lichenoid mucocutaneous erosions during anti-PD-1 immunotherapy in metastatic renal cell carcinoma - A case report

2019 ◽  
Vol 23 ◽  
pp. 1-2 ◽  
Author(s):  
Andrea Katharina Lindner ◽  
Gert Schachtner ◽  
Gennadi Tulchiner ◽  
Nina Staudacher ◽  
Fabian Steinkohl ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell

scholarly journals Long-term response of over ten years with sorafenib monotherapy in metastatic renal cell carcinoma: a case report

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Kosuke Ueda ◽  
Shigetaka Suekane ◽  
Naoyuki Ogasawara ◽  
Katsuaki Chikui ◽  
Shunsuke Suyama ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Term Response

scholarly journals A Case Report of Severe Type B Lactic Acidosis Following First Dose of Nivolumab in a VHL-Mutated Metastatic Renal Cell Carcinoma

Kidney Cancer ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Erica Nakajima ◽  
Paul Leger ◽  
Ingrid A. Mayer ◽  
Michael N. Neuss ◽  
David D. Chism ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Lactic Acidosis ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Type B ◽  
Severe Type
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