Ruthenium arene complexes with mono-carbonyl analogues of curcumin as pendant or bridging ligands: Synthesis, anti-cancer activity and interaction with quadruplex DNA

Polyhedron ◽  
2019 ◽  
Vol 171 ◽  
pp. 396-402
Author(s):  
Jiaming Bi ◽  
Tianle Pay ◽  
Zhen Xuan Wong ◽  
Yan Yi Khong ◽  
Ming Xuan Kueh ◽  
...  
Keyword(s):  
Arene Complexes ◽  
Bridging Ligands ◽  
Quadruplex Dna ◽  
Anti Cancer ◽  
Ruthenium Arene ◽  
Cancer Activity

Synthesis, structure, spectral, redox properties and anti-cancer activity of Ruthenium(II) Arene complexes with substituted Triazole Ligands

2021 ◽  
Vol 954-955 ◽  
pp. 122074
Author(s):  
Arabinda Muley ◽  
Kalai Selvan Karumban ◽  
Parth Gupta ◽  
Sadananda Kumbhakar ◽  
Bishnubasu Giri ◽  
...  
Keyword(s):  
Redox Properties ◽  
Arene Complexes ◽  
Anti Cancer ◽  
Cancer Activity

scholarly journals Ruthenium–arene complexes bearing naphthyl-substituted 1,3-dioxoindan-2-carboxamides ligands for G-quadruplex DNA recognition

2019 ◽  
Vol 48 (32) ◽  
pp. 12040-12049 ◽  
Author(s):  
Laura A. Hager ◽  
Stephan Mokesch ◽  
Claudia Kieler ◽  
Silvia Alonso-de Castro ◽  
Dina Baier ◽  
...  
Keyword(s):  
Dna Recognition ◽  
Arene Complexes ◽  
Quadruplex Dna ◽  
Dna Structures ◽  
G Quadruplex ◽  
Ruthenium Arene

Ru(ii) arene complexes with 1,3-dioxoindan-2-carboxamides ligands bearing pendant naphthyl-groups designed to bind G-quadruplex DNA structures by both stacking and coordinating interactions.

ANTICANCER EFFECT OF UVARIA GENUS

2014 ◽  
pp. 98-101
Author(s):  
Thi Bich Hien Le ◽  
Viet Duc Ho ◽  
Thi Hoai Nguyen
Keyword(s):  
Biological Activities ◽  
Current Trend ◽  
Healthcare Systems ◽  
Chemical Compositions ◽  
Cancer Therapies ◽  
Pharmacological Effects ◽  
Anticancer Effect ◽  
Anti Cancer ◽  
Tropical Areas ◽  
Cancer Activity

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.

Eremurus spectabilis, Rich Source of Isoorientin: Isolation, Quantification and Anti-Cancer Activity on SH-SY5Y Neuroblastoma Cells

2018 ◽  
Vol 14 (6) ◽  
pp. 578-585
Author(s):  
Esen Sezen Karaoglan ◽  
Gulsah Gundogdu ◽  
Mucahit Secme ◽  
Onur Senol ◽  
Fatma Demirkaya Miloglu ◽  
...  
Keyword(s):  
Neuroblastoma Cells ◽  
Rich Source ◽  
Anti Cancer ◽  
Cancer Activity
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