Predictive population balance model development and validation of the effect of high shear wet granulation process parameters on granule properties

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Development And Validation ◽

Population Balance Model Development, Validation, and Prediction of CQAs of a High-Shear Wet Granulation Process: Towards QbD in Drug Product Pharmaceutical Manufacturing

Journal of Pharmaceutical Innovation ◽

10.1007/s12247-014-9172-7 ◽

2014 ◽

Vol 9 (1) ◽

pp. 53-64 ◽

Cited By ~ 23

Author(s):

Anwesha Chaudhury ◽

Dana Barrasso ◽

Preetanshu Pandey ◽

Huiquan Wu ◽

Rohit Ramachandran

Keyword(s):

Drug Product ◽

Model Development ◽

Population Balance ◽

Pharmaceutical Manufacturing ◽

Balance Model ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Compartment based population balance model development of a high shear wet granulation process via dry and wet binder addition

Chemical Engineering Research and Design ◽

10.1016/j.cherd.2017.04.017 ◽

2017 ◽

Vol 123 ◽

pp. 187-200 ◽

Cited By ~ 8

Author(s):

Anik Chaturbedi ◽

Chandra Kanth Bandi ◽

Dheeraj Reddy ◽

Preetanshu Pandey ◽

Ajit Narang ◽

...

Keyword(s):

Model Development ◽

Population Balance ◽

Balance Model ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

A combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics

Pharmaceutical Development and Technology ◽

10.3109/10837450.2012.700933 ◽

2012 ◽

Vol 18 (1) ◽

pp. 210-224 ◽

Cited By ~ 40

Author(s):

Preetanshu Pandey ◽

Jing Tao ◽

Anwesha Chaudhury ◽

Rohit Ramachandran ◽

Julia Z. Gao ◽

...

Keyword(s):

Process Parameters ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Modeling Approach ◽

Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

RSC Advances ◽

10.1039/c7ra05252a ◽

2017 ◽

Vol 7 (61) ◽

pp. 38307-38317 ◽

Cited By ~ 5

Author(s):

F. Shikata ◽

S. Kimura ◽

Y. Hattori ◽

M. Otsuka

Keyword(s):

Infrared Spectroscopy ◽

Real Time ◽

Near Infrared Spectroscopy ◽

Near Infrared ◽

Wet Granulation ◽

High Shear ◽

Monitoring Method ◽

Granulation Process ◽

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

Multi-dimensional population balance model development and validation for a twin screw granulation process

Powder Technology ◽

10.1016/j.powtec.2014.06.035 ◽

2015 ◽

Vol 270 ◽

pp. 612-621 ◽

Cited By ~ 43

Author(s):

Dana Barrasso ◽

Arwa El Hagrasy ◽

James D. Litster ◽

Rohit Ramachandran

Keyword(s):

Model Development ◽

Population Balance ◽

Balance Model ◽

Granulation Process ◽

Twin Screw ◽

Twin Screw Granulation ◽

Development And Validation

A quantitative study of the effect of process parameters on key granule characteristics in a high shear wet granulation process involving a two component pharmaceutical blend

Advanced Powder Technology ◽

10.1016/j.apt.2014.10.012 ◽

2015 ◽

Vol 26 (1) ◽

pp. 315-322 ◽

Cited By ~ 35

Author(s):

Sarang Oka ◽

Ondřej Kašpar ◽

Viola Tokárová ◽

Koushik Sowrirajan ◽

Huiquan Wu ◽

...

Keyword(s):

Quantitative Study ◽

Process Parameters ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Two Component ◽

Effect of Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear wet Granulation Process, Part 3: Effect of Binder Rheological Properties

Journal of Pharmaceutical Sciences ◽

10.1002/jps.23059 ◽

2012 ◽

Vol 101 (5) ◽

pp. 1877-1887 ◽

Cited By ~ 7

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Rheological Properties ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Towards Understanding High-Shear Wet Granulation Process. Part I. Physical Characterization of Binders

Journal of Pharmaceutical Sciences ◽

10.1002/jps.22260 ◽

2011 ◽

Vol 100 (1) ◽

pp. 164-173 ◽

Cited By ~ 12

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Physical Characterization ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

A compartment based population balance model for the prediction of steady and induction granule growth behavior in high shear wet granulation

Advanced Powder Technology ◽

10.1016/j.apt.2021.04.021 ◽

2021 ◽

Author(s):

Indu Muthancheri ◽

Anik Chaturbedi ◽

Angelique Bétard ◽

Rohit Ramachandran

Keyword(s):

Population Balance ◽

Growth Behavior ◽

Balance Model ◽

Wet Granulation ◽

High Shear ◽

Granule Growth

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear Wet Granulation Process. Part II. Granulation and Granule Properties

Journal of Pharmaceutical Sciences ◽

10.1002/jps.22261 ◽

2011 ◽

Vol 100 (1) ◽

pp. 294-310 ◽

Cited By ~ 14

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽