A quantitative study of the effect of process parameters on key granule characteristics in a high shear wet granulation process involving a two component pharmaceutical blend

2015 ◽  
Vol 26 (1) ◽  
pp. 315-322 ◽  
Author(s):  
Sarang Oka ◽  
Ondřej Kašpar ◽  
Viola Tokárová ◽  
Koushik Sowrirajan ◽  
Huiquan Wu ◽  
...  
Keyword(s):  
Quantitative Study ◽  
Process Parameters ◽  
Wet Granulation ◽  
High Shear ◽  
Granulation Process ◽  
Two Component ◽  
High Shear Wet Granulation

Efficient Global Sensitivity-Based Model Calibration of a High-Shear Wet Granulation Process

2021 ◽  
pp. 116569
Author(s):  
Aaron S. Yeardley ◽  
Stefan Bellinghausen ◽  
Robert Milton ◽  
James D. Litster ◽  
Solomon F. Brown
Keyword(s):  
Model Calibration ◽  
Wet Granulation ◽  
High Shear ◽  
Granulation Process ◽  
Global Sensitivity ◽  
High Shear Wet Granulation

scholarly journals Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

RSC Advances ◽  
2017 ◽  
Vol 7 (61) ◽  
pp. 38307-38317 ◽  
Author(s):  
F. Shikata ◽  
S. Kimura ◽  
Y. Hattori ◽  
M. Otsuka
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Wet Granulation ◽  
High Shear ◽  
Monitoring Method ◽  
Granulation Process ◽  
High Shear Wet Granulation ◽  
Granule Properties

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

scholarly journals Scale-Up Studies on High Shear Wet Granulation Process from Mini-Scale to Commercial Scale

2008 ◽  
Vol 56 (10) ◽  
pp. 1431-1435 ◽  
Author(s):  
Shouhei Aikawa ◽  
Naomi Fujita ◽  
Hidetoshi Myojo ◽  
Takashi Hayashi ◽  
Tadatsugu Tanino
Keyword(s):  
Scale Up ◽  
Wet Granulation ◽  
High Shear ◽  
Granulation Process ◽  
Commercial Scale ◽  
High Shear Wet Granulation

Development of low dose micro-tablets by high shear wet granulation process

2020 ◽  
Vol 587 ◽  
pp. 119571 ◽  
Author(s):  
Shashwat Gupta ◽  
Prajwal Thool ◽  
Saikishore Meruva ◽  
Jianmin Li ◽  
Jhalak Patel ◽  
...  
Keyword(s):  
Low Dose ◽  
Wet Granulation ◽  
High Shear ◽  
Granulation Process ◽  
High Shear Wet Granulation
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