Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

Near Infrared ◽

Wet Granulation ◽

High Shear ◽

Monitoring Method ◽

Granulation Process ◽

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

Computer Aided Chemical Engineering - 11th International Symposium on Process Systems Engineering ◽

De-risking Scale-up of a High Shear Wet Granulation Process Using Latent Variable Modeling and Near Infrared Spectroscopy

10.1016/b978-0-444-59506-5.50050-x ◽

2012 ◽

pp. 1095-1099 ◽

Cited By ~ 2

Author(s):

Koji Muteki ◽

Ken Yamamoto ◽

George L. Reid ◽

Mahesh Krishnan

Keyword(s):

Infrared Spectroscopy ◽

Latent Variable ◽

Near Infrared ◽

Scale Up ◽

Latent Variable Modeling ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

High Shear Wet Granulation

De-risking Scale-up of a High Shear Wet Granulation Process Using Latent Variable Modeling and Near-Infrared Spectroscopy

Journal of Pharmaceutical Innovation ◽

10.1007/s12247-011-9110-x ◽

2011 ◽

Vol 6 (3) ◽

pp. 142-156 ◽

Cited By ~ 19

Author(s):

Koji Muteki ◽

Ken Yamamoto ◽

George L. Reid ◽

Mahesh Krishnan

Keyword(s):

Infrared Spectroscopy ◽

Latent Variable ◽

Near Infrared ◽

Scale Up ◽

Latent Variable Modeling ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

High Shear Wet Granulation

Analysis of granulation mechanism in a high-shear wet granulation method using near-infrared spectroscopy and stirring power consumption

Colloid & Polymer Science ◽

10.1007/s00396-020-04655-y ◽

2020 ◽

Vol 298 (8) ◽

pp. 977-987 ◽

Cited By ~ 1

Author(s):

Keita Koyanagi ◽

Akinori Ueno ◽

Yusuke Hattori ◽

Tetsuo Sasaki ◽

Tomoaki Sakamoto ◽

...

Keyword(s):

Infrared Spectroscopy ◽

Power Consumption ◽

Near Infrared ◽

Wet Granulation ◽

High Shear ◽

Granulation Mechanism

Predictive population balance model development and validation of the effect of high shear wet granulation process parameters on granule properties

Powder Technology ◽

10.1016/j.powtec.2018.07.004 ◽

2018 ◽

Vol 338 ◽

pp. 391-401 ◽

Cited By ~ 3

Author(s):

Anik Chaturbedi ◽

Preetanshu Pandey ◽

Dilbir Bindra ◽

Jay Poorna Reddy ◽

Bo Lang ◽

...

Keyword(s):

Process Parameters ◽

Model Development ◽

Balance Model ◽

Population Balance Model ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Development And Validation ◽

Effect of Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear wet Granulation Process, Part 3: Effect of Binder Rheological Properties

10.1002/jps.23059 ◽

2012 ◽

Vol 101 (5) ◽

pp. 1877-1887 ◽

Cited By ~ 7

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Rheological Properties ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

Comparison of torque measurements and near-infrared spectroscopy in characterization of a wet granulation process

10.1002/jps.20132 ◽

2004 ◽

Vol 93 (9) ◽

pp. 2232-2243 ◽

Cited By ~ 31

Author(s):

Anna Cecilia Jørgensen ◽

Pirjo Luukkonen ◽

Jukka Rantanen ◽

Torben Schæfer ◽

Anne Mari Juppo ◽

...

Keyword(s):

Infrared Spectroscopy ◽

Near Infrared ◽

Wet Granulation ◽

Granulation Process ◽

Torque Measurements

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Towards Understanding High-Shear Wet Granulation Process. Part I. Physical Characterization of Binders

10.1002/jps.22260 ◽

2011 ◽

Vol 100 (1) ◽

pp. 164-173 ◽

Cited By ~ 12

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Physical Characterization ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear Wet Granulation Process. Part II. Granulation and Granule Properties

10.1002/jps.22261 ◽

2011 ◽

Vol 100 (1) ◽

pp. 294-310 ◽

Cited By ~ 14

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical State of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach to Understand the High-Shear Wet Granulation Process. Part IV. The Impact of Rheological State and Tip-speeds

10.1002/jps.23750 ◽

2013 ◽

Vol 102 (12) ◽

pp. 4384-4394 ◽

Cited By ~ 3

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Physical State ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Impact ◽

Efficient Global Sensitivity-Based Model Calibration of a High-Shear Wet Granulation Process

Chemical Engineering Science ◽

10.1016/j.ces.2021.116569 ◽

2021 ◽

pp. 116569

Author(s):

Aaron S. Yeardley ◽

Stefan Bellinghausen ◽

Robert Milton ◽

James D. Litster ◽

Solomon F. Brown

Keyword(s):

Model Calibration ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Global Sensitivity ◽

High Shear Wet Granulation