Preliminary Characterization and Comparison of Mucilage from Leaves of Hibiscus Sabdariffa L. as A Tablet Binder

The present research dealt with the extraction and characterization of mucilage from the Hibiscus sabdariffa leaves. Compared with normal binding agents such as starch and Poly Vinyl Pyrrolidine (PVP), the mucilage of Hibiscus sabdariffa (HSM) was assessed for its binding properties in tablet formulations. Tablets were formulated using HSM, starch and PVP as binders at a various concentration to evaluate its comparative binding efficiency. The compressed tablets were analyze for their quality control tests as per IP. The extracted HSM showed the characteristics of mucilage and good physicochemical properties. The FTIR and thermal analysis compatibility tests showed that there were no significant reactions between the drug and mucilage. Granule properties of various formulations were found to be comparable and have excellent flow characteristics. Post compression parameters suggested that tablets formulated with mucilage had better hardness and friability as that of the tablets prepared with starch and PVP. The formulations exhibited a better and more consistent release as compared to standard formulations using starch and PVP as a binder. The statistical analysis of in vitro dissolution profile by using DD solver software for difference factor (f1), similarity factor (f2), and Rescigno index (ξ) values also indicated promising results. The results notably indicate that binding property of HSM was at par with starch and PVP.

Filter Medias from Granulated Foam-glass, Properties Investigated for Water Treatment Possibilities

Inorganic material – granulated foam-glass produced from glass breakage in small porous granule shape. Foam-glass is gotten by connecting thoroughly grounded glass with foamers, later this composition is heated in the furnace in especially high temperature and is turned into various diameter greyish granules. Granulated foam-glass is a unique ecological material of which inner structure pores are arranged in such a way that air is trapped inside. Foam-glass production technology is one of the most advanced since the product is made from secondary raw materials, not leaving any third row waste. From granule surface images it can be seen that granule surface has pores and voids, some of these pores are closed, others are connected with granule’s inner pores, all pore walls are smooth, and the wall material is vitrified. Pores and voids are arranged chaotically in smaller granules, bigger granules inner space structure is tidy, bigger part is occupied by correctly arranged bigger pores and space between them is filled with smaller pores. Granules are composed of amorphous phase, in mineralogical composition can emit one material cristobalite. In the work were researched two fraction granules: 0/2 and 2/4 as well as determined 0/4 fraction granular-metric composition. Researched and determined main physical granule properties and properties related to water effect to the material, shown in micro-structural granule surface and inner structure images. According to explored properties it can be noted that granules can be adapted in water cleaning technologies.