ANTI-INFLAMMATORY AND MOLECULAR DOCKING ANALYSIS OF LEUCAS VESTITA Wall. Ex. Benth. EXTRACT AGAINST CYCLO-OXYGENASE-2

2021 ◽  
pp. 106581
Author(s):  
S.V. Rajesh ◽  
T.S. Gnanendra ◽  
T. Senthil Kumar
Keyword(s):  
Molecular Docking ◽  
Docking Analysis ◽  
Anti Inflammatory ◽  
Molecular Docking Analysis

scholarly journals Molecular docking analysis of furfural and isoginkgetin with heme oxygenase I and PPARγ

2021 ◽  
Vol 17 (2) ◽  
pp. 356-362
Author(s):  
Preetha Santhakumar ◽  
Keyword(s):  
Molecular Docking ◽  
Cascade Process ◽  
Docking Analysis ◽  
Target Proteins ◽  
Hydrogen Bond Interactions ◽  
Tnf Α ◽  
Anti Inflammatory ◽  
Factor Α ◽  
Necrosis Factor ◽  
Molecular Docking Analysis

Inflammatory is cascade process triggered by pro-inflammatory cytokines and anti-inflammatory. In the present study anti-inflammatory activity of Stachydrine and Sakuranetin were studied against the inflammatory target proteins IL-6 and TNF-α by using molecular docking analysis. Both compounds showed the good binding with selected target proteins. Compared to Sakuranetin, the Stachydrine have lowest binding energy and good hydrogen bond interactions. Hence results of study indicated that Stachydrine possessed high and specific inhibitory activity on tumor necrosis factor-α and interleukin-6.

Evaluation of Analgesic and Anti-Inflammatory Activities and Molecular Docking Analysis of Steroidal Lactones from Datura stramonium L.

Phytomedicine ◽  
2021 ◽  
pp. 153621
Author(s):  
Gourav Chandan ◽  
Chetan Kumar ◽  
Pankaj Chibber ◽  
Ashwani Kumar ◽  
Gurdashan Singh ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Datura Stramonium ◽  
Docking Analysis ◽  
Anti Inflammatory ◽  
Molecular Docking Analysis

scholarly journals Molecular docking analysis of stachydrine and sakuranetin with IL-6 and TNF-α in the context of inflammation

2021 ◽  
Vol 17 (2) ◽  
pp. 348-355
Author(s):  
Lavanya Prathap ◽  
Keyword(s):  
Molecular Docking ◽  
Cascade Process ◽  
Docking Analysis ◽  
Target Proteins ◽  
Hydrogen Bond Interactions ◽  
Tnf Α ◽  
Anti Inflammatory ◽  
Factor Α ◽  
Necrosis Factor ◽  
Molecular Docking Analysis

Inflammatory is cascade process triggered by pro-inflammatory cytokines and anti-inflammatory. In the present study anti-inflammatory activity of Stachydrine and Sakuranetin were studied against the inflammatory target proteins IL-6 and TNF-α by using molecular docking analysis. Both compounds showed the good binding with selected target proteins. Compared to Sakuranetin, the Stachydrine have lowest binding energy and good hydrogen bond interactions. Hence results of study indicated that Stachydrine possessed high and specific inhibitory activity on tumor necrosis factor-α and interleukin-6.

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