The relation of salivary cortisol to patterns of performance on a word list learning task in healthy older adults

2008 ◽  
Vol 33 (9) ◽  
pp. 1293-1296 ◽  
Author(s):  
Julie Suhr ◽  
Petya Demireva ◽  
Kathi Heffner
2017 ◽  
Vol 30 (8) ◽  
pp. 1235-1242 ◽  
Author(s):  
Alessia Rosi ◽  
Federica Del Signore ◽  
Elisa Canelli ◽  
Nicola Allegri ◽  
Sara Bottiroli ◽  
...  

ABSTRACTBackground:Previous research has suggested that there is a degree of variability among older adults’ response to memory training, such that some individuals benefit more than others. The aim of the present study was to identify the profile of older adults who were likely to benefit most from a strategic memory training program that has previously proved to be effective in improving memory in healthy older adults.Method:In total, 44 older adults (60–83 years) participated in a strategic memory training. We examined memory training benefits by measuring changes in memory practiced (word list learning) and non-practiced tasks (grocery list and associative learning). In addition, a battery of cognitive measures was administered in order to assess crystallized and fluid abilities, short-term memory, working memory, and processing speed.Results:Results confirmed the efficacy of the training in improving performance in both practiced and non-practiced memory tasks. For the practiced memory tasks, results showed that memory baseline performance and crystallized ability predicted training gains. For the non-practiced memory tasks, analyses showed that memory baseline performance was a significant predictor of gain in the grocery list learning task. For the associative learning task, the significant predictors were memory baseline performance, processing speed, and marginally the age.Conclusions:Our results indicate that older adults with a higher baseline memory capacity and with more efficient cognitive resources were those who tended to benefit most from the training. The present study provides new avenues in designing personalized intervention according to the older adults’ cognitive profile.


2008 ◽  
Vol 78 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ellen E.A. Simpson ◽  
Chris McConville ◽  
Gordon Rae ◽  
Jacqueline M. O’Connor ◽  
Barbara J. Stewart-Knox ◽  
...  

2014 ◽  
Vol 29 (6) ◽  
pp. 535-535
Author(s):  
C. Funes ◽  
J. Diaz ◽  
C. Clendinen ◽  
F. Goldstein ◽  
J. Razani ◽  
...  

2006 ◽  
Vol 14 (7S_Part_18) ◽  
pp. P972-P972 ◽  
Author(s):  
Emiliano Albanese ◽  
Martin Preisig ◽  
Enrique Castelao ◽  
Sami Ouanes ◽  
Julius Popp

2021 ◽  
pp. 174702182110207
Author(s):  
Christopher Hilton ◽  
Jan Wiener ◽  
Andrew Johnson

The present study demonstrates similarities between route learning and classical tests of serial order memory. Here, we investigated serial memory for landmarks in a route learning task, in younger and older adults. We analysed data from a route learning task with 12 landmarks, reported by Hilton et al. (2021). Participants (88 younger and 77 older) learned a route using either a Fixed Learning (3 exposures to the route) or Flexible Learning (repeated exposures until successful navigation was achieved) procedure. Following route learning, participants completed Immediate Free Recall (IFR) and Free Reconstruction of Order (Free RoO) of the landmarks. We show clear acquisition of sequence memory for landmarks for both age groups, with Free RoO producing a bowed serial position curve. IFR produced recency effects but no primacy effects in fixed learning, with recency reduced following flexible learning for both age groups. Younger adults displayed a primacy bias for the first item recalled in both learning conditions, as did the older adults in the flexible learning condition. In contrast, older adults displayed a recency bias in the fixed learning condition. Evidence of contiguity in IFR was present only for younger adults in the flexible learning condition. Findings are broadly consistent with results from typical short-term list learning procedures and support the universality of sequence learning effects, which we demonstrate are generalisable to a navigation context.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S27-S27
Author(s):  
Anam M Khan ◽  
Philippa Clarke ◽  
Jessica Finlay ◽  
Carina Gronlund ◽  
Robert Melendez ◽  
...  

Abstract Research on temperature and cognition is sparse, including effects of outdoor air temperature on cognitive testing performance. Furthermore, little is known about the modifying role of region and seasonality in temperature-cognition associations. We linked daily temperature data from National Oceanic and Atmospheric Administration weather stations to REGARDS participants by cognitive assessment date. Controlling for season, generalized linear models including spline terms for temperature showed an adverse effect of hotter temperatures on cognition. At higher temperatures (30°C vs 0°C), there was a significant decrease in cognitive performance on the Word List Learning test (β=-0.68; 95% CI: -1.1, -0.25). Results also show regional differences in testing scores on hotter and colder days. The findings provide new understanding of cognitive susceptibility to extreme temperatures and factors that exacerbate or buffer this association. This can inform development of evidence-based public health guidelines and mitigation strategies aimed at reducing temperature-related morbidity in older adults.


2007 ◽  
Vol 14 (1) ◽  
pp. 70-94 ◽  
Author(s):  
Kelly J. Murphy ◽  
Robert West ◽  
Maria L. Armilio ◽  
Fergus I. M. Craik ◽  
Donald T. Stuss

2019 ◽  
Vol 15 (1) ◽  
pp. 54-62 ◽  
Author(s):  
O. D. Ostroumova ◽  
E. V. Borisova ◽  
A. I. Kochetkov ◽  
T. M. Ostroumova ◽  
O. V. Bondarec

Different antihypertensive drugs differently affect cognitive function, and data on the effect of single-pill combination (SPC) of antihypertensive drugs on cognitive function are presented only in single studies.Aim. To investigate the impact of amlodipine/valsartan SPC (A/V SPC) on blood pressure (BP) level and cognitive functions in the middle-aged antihypertensive treatment-naive patients with stage II grade 1-2 essential arterial hypertension.Methods. A group of patients with stage II grade 1-2 essential arterial hypertension who had not previously received regular antihypertensive treatment (n=38, age 49.7±7.0 years) was retrospectively formed. All the patients were treated with A/V SPC and all of them achieved target office BP (less than 140/90 mm Hg). And after 12-week follow-up (since the time of reaching the target BP) the antihypertensive treatment efficacy assessment using ambulatory BP monitoring (ABPM) were performed in all included hypertensive patients. Age-matched healthy people with normal BP (n=20, mean age 45.4±5.1years) represented a control group. In all participants cognitive functions were evaluated by 5 different tests at baseline and at the end of follow-up: Montreal Cognitive Assessment (MoCA); Trail Making test (part A and part B), Stroop Color and Word Test; verbal fluency test; 10-item word list learning task. Baseline Hamilton depression and anxiety rating scale data were also available in all individuals.Results. According to the ABPM data 24-hour, day-time and night-time systolic, diastolic and pulse BP significantly decreased after the treatment with A/V SPC (p<0.001 for systolic and diastolic BP and p<0.01 for pulse BP). After the treatment with A/V SPC significantly improved results of cognitive tests in hypertensive patients: decreased time in Trail Making Test part B (from 114.7±37.0 to 96.3±26.5 s; р=0.001); time difference between part B and part A of Trail Making Test (from 75.2±32.8 to 57.7±20.1 s; р=0.002); time in Stroop test part 3 (from 117.0±28.1 to 108.0±28.4 s; р=0.013); and interference score (from 50.9±19.2 to 43.1±22.0 s; р=0.011); increased MoCA score (from 28.4±1.3 to 29.4±1.2; р=0.001); as well as increased the 10-item word list learning task – immediate recall (from 5.7±1.3 to 6.5±1.2 words; р=0.001); 10-item word list learning task – delayed recall (from 6.3±2.1 to 6.9±1.7 words; р=0.006); literal fluency (from 11.7±3.4 to 13.2±3.2 words; р=0.020) and categorical fluency (from 7.3±2.5 to 9.5±2.9 words; p<0.001). In control group at the end of follow-up compared to baseline significantly increased the 10-item word list learning task – immediate recall (from 5.8±0.9 to 6.6±1.1 words; р<0.05) and delayed recall (from 5.9±1.8 to 8.2±1.4 words; р<0.001).Conclusion. In retrospective analysis improvement of cognitive function was found in middle-aged patients with hypertension, taking A/V SPC for 12 weeks after reaching the target BP. 


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