Pattern of lymph node metastases and its implication in radiotherapeutic clinical target volume in patients with thoracic esophageal squamous cell carcinoma: A report of 1077 cases

2010 ◽  
Vol 95 (2) ◽  
pp. 229-233 ◽  
Author(s):  
Wei Huang ◽  
Baosheng Li ◽  
Heyi Gong ◽  
Jinming Yu ◽  
Hongfu Sun ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymph Node Metastases ◽  
Clinical Target Volume ◽  
Target Volume ◽  
Node Metastases

Implication of clinical target delineation for T1b/T2 thoracic esophageal squamous cell carcinoma based on the pattern of lymph node metastases

2019 ◽  
Vol 15 (29) ◽  
pp. 3345-3355
Author(s):  
Hui Guan ◽  
Yang Yu ◽  
Hong Ge ◽  
Shuchai Zhu ◽  
Wei Huang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymph Node Metastases ◽  
Target Delineation ◽  
Tumor Length ◽  
Node Metastases ◽  
Upper Thoracic

Aim: This study aimed to explore different patterns of lymph node metastases (LNM) in T1b and T2 thoracic esophageal squamous cell carcinoma (ESCC), and to further clarify its significance in radiotherapy target delineation. Materials & methods: Data of 1960 patients with T1b and T2 thoracic ESCC treated at different cancer centers were retrospectively analyzed. All patients underwent esophagectomy and lymphadenectomy. χ2 test and multivariate analysis were applied for analyzing clinicopathological factors related to LNM. Results: Age, location, tumor length, T stage and pathological grade were significantly associated with LNM (p < 0.01). For T1b ESCC, LNM rates in all sites were below 15%. For T2 upper thoracic ESCC, LNM rates were over 15% in upper mediastinal (15.8%). For T2 middle thoracic ESCC, LNM rates were middle mediastinal (17.2%) and abdominal (15.5%). For T2 lower thoracic ESCC, LNM rates were lower mediastinal (24.9%) and abdominal (22.5%). Subgroup analysis of T2 middle thoracic ESCC demonstrated that for patients older than 60 years, tumor length <4 cm and tumors were well differentiated. The LNM rates for abdominal were 11.9, 12.7 and 9.9%. Conclusion: Given the different patterns of LNM between T1b and T2 thoracic ESCC, target delineation should be adjusted accordingly.

scholarly journals Prevalence of lymph node metastases in superficial esophageal squamous cell carcinoma

2013 ◽  
Vol 146 (5) ◽  
pp. 1198-1203 ◽  
Author(s):  
Bin Li ◽  
Haiquan Chen ◽  
Jiaqing Xiang ◽  
Yawei Zhang ◽  
Yunyi Kong ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymph Node Metastases ◽  
Node Metastases
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