Impact of maladaptive behavior on school function in Down syndrome

2016 ◽  
Vol 59 ◽  
pp. 328-337 ◽  
Author(s):  
Elizabeth A. Will ◽  
Brianne Gerlach-McDonald ◽  
Deborah J. Fidler ◽  
Lisa A. Daunhauer
2019 ◽  
Vol 39 (5) ◽  
pp. 461-476 ◽  
Author(s):  
Elizabeth A. Will ◽  
Lisa A. Daunhauer ◽  
Deborah J. Fidler ◽  
Nancy Raitano Lee ◽  
Cordelia Robinson Rosenberg ◽  
...  

2014 ◽  
Vol 68 (2) ◽  
pp. 167-176 ◽  
Author(s):  
L. A. Daunhauer ◽  
D. J. Fidler ◽  
E. Will

2021 ◽  
Vol 126 (4) ◽  
pp. 307-323
Author(s):  
Anna J. Esbensen ◽  
Emily K. Hoffman ◽  
Rebecca C. Shaffer ◽  
Lina R. Patel ◽  
Lisa M. Jacola

Abstract The current study evaluates the concurrent relationship between parent ratings of executive functioning and maladaptive behavior among children and adolescents with Down syndrome and then repeats this evaluation using teacher reports. Parents and teachers of 63 school-age children with Down syndrome rated the child's executive functioning (Behavior Rating Inventory of Executive Function) and behaviors (Achenbach Child Behavior Checklist). For parent and teacher ratings, elevated behavior dysregulation predicted higher levels of rule-breaking, aggressive, and externalizing behavior. For teacher ratings, elevated behavior dysregulation also predicted higher levels of inattention problems. Among both parent and teacher ratings, greater metacognitive difficulties predicted challenges with attention. Understanding the relationship between these constructs has important implications for targets of intervention and developing preventative strategies.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Marie Moore Channell ◽  
◽  
Laura J. Mattie ◽  
Debra R. Hamilton ◽  
George T. Capone ◽  
...  

Abstract Background There is a high degree of inter- and intra-individual variability observed within the phenotype of Down syndrome. The Down Syndrome Cognition Project was formed to capture this variability by developing a large nationwide database of cognitive, behavioral, health, and genetic information on individuals with Down syndrome, ages 6–25 years. The current study used the Down Syndrome Cognition Project database to characterize cognitive and behavioral variability among individuals with Down syndrome. Methods Latent profile analysis was used to identify classes across a sample of 314 participants based on their cognition (IQ and executive functioning), adaptive and maladaptive behavior, and autism spectrum disorder symptomatology. A multivariate multinomial regression model simultaneously examined demographic correlates of class. Results Results supported a 3-class model. Each class demonstrated a unique profile across the subdomains of cognition and behavior. The “normative” class was the largest (n = 153, 48%) and displayed a relatively consistent profile of cognition and adaptive behavior, with low rates of maladaptive behavior and autism symptomatology. The “cognitive” class (n = 109, 35%) displayed low cognitive scores and adaptive behavior and more autism symptomatology, but with low rates of maladaptive behavior. The “behavioral” class, the smallest group (n = 52, 17%), demonstrated higher rates of maladaptive behavior and autism symptomatology, but with cognition levels similar to the “normative” class; their adaptive behavior scores fell in between the other two classes. Household income and sex were the only demographic variables to differ among classes. Conclusions These findings highlight the importance of subtyping the cognitive and behavioral phenotype among individuals with Down syndrome to identify more homogeneous classes for future intervention and etiologic studies. Results also demonstrate the feasibility of using latent profile analysis to distinguish subtypes in this population. Limitations and future directions are discussed.


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Tovi Anderson ◽  
Allison Buterbaugh ◽  
Kaitlin Love ◽  
Jeannie Visootsak

Down syndrome is the most common identifiable genetic cause of intellectual disability, with a unique physical gestalt that makes diagnosis possible during the newborn period. However, the physical characteristics of Fragile X syndrome are fairly subtle, resulting in the first clinical suspicion often arising from delayed developmental milestones. In addition, maladaptive behavior and autistic-like tendencies, such as hand flapping, poor eye contact, and hand biting, may be noted in Fragile X syndrome but are not as commonly observed in Down syndrome. Recognition of a potential secondary diagnosis, such as Fragile X syndrome, in individuals with Down syndrome is critical because there have been advances in targeted pharmacologic treatments for both conditions. Thus, an accurate diagnosis has implications in improving the individual's quality of life.


1976 ◽  
Vol 112 (10) ◽  
pp. 1397-1399 ◽  
Author(s):  
D. M. Carter

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