Temporal lobe gray matter in schizophrenia spectrum: A volumetric MRI study of the fusiform gyrus, parahippocampal gyrus, and middle and inferior temporal gyri

2006 ◽  
Vol 87 (1-3) ◽  
pp. 116-126 ◽  
Author(s):  
Tsutomu Takahashi ◽  
Michio Suzuki ◽  
Shi-Yu Zhou ◽  
Ryoichiro Tanino ◽  
Hirofumi Hagino ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Gray Matter ◽  
Fusiform Gyrus ◽  
Parahippocampal Gyrus ◽  
Volumetric Mri ◽  
Schizophrenia Spectrum ◽  
Mri Study

scholarly journals Evaluation of Brain Structure Based on Voxel and Surface Morphology in Adults with MRI Negative Temporal Lobe Epilepsy

2022 ◽  
Author(s):  
Fan Yang ◽  
Hanjiaerbieke Kukun ◽  
Wenxiao Jia ◽  
Shuang Ding ◽  
Wei Zhao ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Gray Matter ◽  
Age Of Onset ◽  
Morphological Changes ◽  
Fusiform Gyrus ◽  
Parahippocampal Gyrus ◽  
Middle Temporal Gyrus ◽  
Control Group ◽  
Middle Temporal

Abstract Background MRI-negative TLE (TLE-N) is a manifestation lacks visible MRI findings yet with detectable electrophysiological changes. In this study, differences of gray matter in drug-controlled MRI negative temporal lobe epilepsy (cTLE-N) and drug-resistant MRI negative temporal lobe epilepsy (rTLE-N) patients were calculated and analyzed by voxel-based morphology (VBM) and surface-based morphology (SBM), to discover the brain structural changes of TLE-N patients. Materials and methods Consecutive resident patients with 30 cTLE-N and 21 rTLE-N were recruited into respective groups, and 30 healthy controls’ structural MRI (sMRI) data collected as a control group. Open-source software based on VBM and SBM was deployed as gray matter volume (GMV) and cortical thickness (CT) analytic tools. Results VBM analysis showed that GMV of bilateral thalamus and right lingual gyrus of cTLE-N group, and left hippocampus, left fusiform gyrus and left thalamus of rTLE-N group were smaller compared to HC group(FDR corrected, P<0.05), while right cerebellum, inferior temporal gyrus, hippocampus, parahippocampal gyrus, amygdala, fusiform gyrus, orbital middle frontal gyrus, and left posterior central gyrus in cTLE-N group, and bilateral cerebellum and middle temporal gyrus, right fusiform gyrus, amygdala, hippocampus, and left middle occipital gyrus of rTLE-N group were greater than HC group(FDR corrected, P<0.05). SBM analysis showed that CT of the left medial orbitofrontal cortex and lateral occipital cortex in cTLE-N group, and thickness of the left medial orbitofrontal, temporal pole, middle temporal gyrus and right anterior superior cingulate cortex in rTLE-N group were thinner, compared to HC group. Correlation analysis showed that GMV and CT of different structures were correlated with age of onset, disease duration, and MoCA score. Conclusion This study utilized two different sMRI analytic tools and discovered several brain morphological changes in TLE-N. These morphological changes were also correlated with clinical variables. Further study may indicate the potential of these findings on the recognition of the TLE-N epilepsy network.

Subtemporal transparahippocampal amygdalohippocampectomy for surgical treatment of mesial temporal lobe epilepsy

1996 ◽  
Vol 1 (4) ◽  
pp. E2 ◽  
Author(s):  
T. S. Park ◽  
Blaise F. D. Bourgeois ◽  
Daniel L. Silbergeld ◽  
W. Edwin Dodson
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Pediatric Patients ◽  
Mesial Temporal Lobe Epilepsy ◽  
Fusiform Gyrus ◽  
Parahippocampal Gyrus ◽  
Middle Temporal Gyrus ◽  
Language Mapping ◽  
Mesial Temporal Lobe ◽  
Sodium Amobarbital

Amygdalohippocampectomy (AH) is an accepted surgical option for treatment of medically refractory mesial temporal lobe epilepsy. Operative approaches to the amygdala and hippocampus that previously have been reported include: the sylvian fissure, the superior temporal sulcus, the middle temporal gyrus, and the fusiform gyrus. Regardless of the approach, AH permits not only extirpation of an epileptogenic focus in the amygdala and anterior hippocampus, but interruption of pathways of seizure spread via the entorhinal cortex and the parahippocampal gyrus. The authors report a modification of a surgical technique for AH via the parahippocampal gyrus, in which excision is limited to the anterior hippocampus, amygdala and parahippocampal gyrus while preserving the fusiform gyrus and the rest of the temporal lobe. Because transparahippocampal AH avoids injury to the fusiform gyrus and the lateral temporal lobe, it can be performed without intracarotid sodium amobarbital testing of language dominance and language mapping. Thus the operation would be particularly suitable for pediatric patients in whom intraoperative language mapping before resection is difficult.

Sex-Linked Differences in the Anatomy of the Perisylvian Language Cortex: A Volumetric MRI Study of Gray Matter Volumes.

2004 ◽  
Vol 18 (4) ◽  
pp. 738-747 ◽  
Author(s):  
Tracey A. Knaus ◽  
Angela M. Bollich ◽  
David M. Corey ◽  
Lisa C. Lemen ◽  
Anne L. Foundas
Keyword(s):  
Gray Matter ◽  
Volumetric Mri ◽  
Mri Study ◽  
Gray Matter Volumes ◽  
Language Cortex

Volumetric MRI study of the short and long insular cortices in schizophrenia spectrum disorders

2005 ◽  
Vol 138 (3) ◽  
pp. 209-220 ◽  
Author(s):  
Tsutomu Takahashi ◽  
Michio Suzuki ◽  
Shi-Yu Zhou ◽  
Hirofumi Hagino ◽  
Ryoichiro Tanino ◽  
...  
Keyword(s):  
Schizophrenia Spectrum Disorders ◽  
Volumetric Mri ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
Mri Study

282 A Follow-up MRI Study of the Temporal Lobe Structures in Schizophrenia Spectrum

2011 ◽  
Vol 4 ◽  
pp. S67-S68
Author(s):  
T. Takahashi ◽  
S.-Y. Zhou ◽  
K. Nakamura ◽  
A. Furuichi ◽  
M. Kido ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Schizophrenia Spectrum ◽  
Mri Study

Altered White Matter/Gray Matter Proportions in the Striatum of Patients With Schizophrenia: A Volumetric MRI Study

2005 ◽  
Vol 162 (12) ◽  
pp. 2315-2321 ◽  
Author(s):  
Chiharu Tamagaki ◽  
Göran C. Sedvall ◽  
Erik G. Jönsson ◽  
Gaku Okugawa ◽  
Håkan Hall ◽  
...  
Keyword(s):  
White Matter ◽  
Gray Matter ◽  
Volumetric Mri ◽  
Mri Study

A volumetric MRI study of the hippocampus and the parahippocampal region after unilateral medial temporal lobe resection

2006 ◽  
Vol 156 (1-2) ◽  
pp. 293-304 ◽  
Author(s):  
M. Noulhiane ◽  
S. Samson ◽  
S. Clémenceau ◽  
D. Dormont ◽  
M. Baulac ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Medial Temporal Lobe ◽  
Volumetric Mri ◽  
Temporal Lobe Resection ◽  
Mri Study

Morphological brain changes associated with Schneider's first-rank symptoms in schizophrenia: an MRI study

2004 ◽  
Vol 35 (4) ◽  
pp. 549-560 ◽  
Author(s):  
M. SUZUKI ◽  
S.-Y. ZHOU ◽  
H. HAGINO ◽  
L. NIU ◽  
T. TAKAHASHI ◽  
...  
Keyword(s):  
Gray Matter ◽  
Parahippocampal Gyrus ◽  
Precentral Gyrus ◽  
Cingulate Gyrus ◽  
Self Monitoring ◽  
Healthy Control ◽  
And Gender ◽  
The Right ◽  
Mri Study ◽  
First Rank Symptoms

Background. Schneider's first-rank symptoms involve an alienated feature of the sense of one's own mental or physical activity. To clarify the brain morphological basis for the production of these symptoms, volumes of the frontal and medial temporal regions and their clinical correlates were examined in patients with schizophrenia.Method. Twenty-two patients with schizophrenia and 44 age- and gender-matched healthy control subjects were included. All patients were in their psychotic episodes with definite Schneiderian symptoms, rated by using the Scale for Assessment of Positive Symptoms. Volumetric measurements of high-resolution magnetic resonance imaging were performed in the prefrontal area, cingulate gyrus, and precentral gyrus, and the medial temporal structures such as the amygdala, hippocampus, and parahippocampal gyrus.Results. Patients had significantly decreased volumes in the cingulate gray matter and the amygdala compared to controls. In the patient group, Schneiderian symptom severity showed significant inverse correlations with volumes of the right posterior cingulate gray matter and of the left anterior parahippocampal gyrus.Conclusions. Schneiderian symptoms may be associated with morphological abnormalities in the limbic-paralimbic regions such as the cingulate gyrus and parahippocampal gyrus, which possibly serve the self-monitoring function and the coherent storage and reactivation of information.

Subtemporal transparahippocampal amygdalohippocampectomy for surgical treatment of mesial temporal lobe epilepsy

1996 ◽  
Vol 85 (6) ◽  
pp. 1172-1176 ◽  
Author(s):  
T. S. Park ◽  
Blaise F. D. Bourgeois ◽  
Daniel L. Silbergeld ◽  
W. Edwin Dodson
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Mesial Temporal Lobe Epilepsy ◽  
Fusiform Gyrus ◽  
Parahippocampal Gyrus ◽  
Middle Temporal Gyrus ◽  
Language Mapping ◽  
Content Type ◽  
Mesial Temporal Lobe ◽  
Sodium Amobarbital

✓ Amygdalohippocampectomy (AH) is an accepted surgical option for treatment of medically refractory mesial temporal lobe epilepsy. Operative approaches to the amygdala and hippocampus that previously have been reported include: the sylvian fissure, the superior temporal sulcus, the middle temporal gyrus, and the fusiform gyrus. Regardless of the approach, AH permits not only extirpation of an epileptogenic focus in the amygdala and anterior hippocampus, but interruption of pathways of seizure spread via the entorhinal cortex and the parahippocampal gyrus. The authors report a modification of a surgical technique for AH via the parahippocampal gyrus, in which excision is limited to the anterior hippocampus, amygdala and parahippocampal gyrus while preserving the fusiform gyrus and the rest of the temporal lobe. Because transparahippocampal AH avoids injury to the fusiform gyrus and the lateral temporal lobe, it can be performed without intracarotid sodium amobarbital testing of language dominance and language mapping. Thus the operation would be particularly suitable for pediatric patients in whom intraoperative language mapping before resection is difficult.

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