scholarly journals Danish study of a Modified Atkins diet for medically intractable epilepsy in children: Can we achieve the same results as with the classical ketogenic diet?

Seizure ◽  
2011 ◽  
Vol 20 (2) ◽  
pp. 151-155 ◽  
Author(s):  
Maria J. Miranda ◽  
Mette Mortensen ◽  
Jane H. Povlsen ◽  
Helle Nielsen ◽  
Sándor Beniczky
Keyword(s):  
Ketogenic Diet ◽  
Intractable Epilepsy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Danish Study

scholarly journals Comparison of the Effect of Classical Ketogenic Diet and Modified Atkins Diet on Lipid Profile in Patients with Intractable Epilepsy

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1139-1139
Author(s):  
Shahabeddin Rezaei ◽  
Mona Kavoosi ◽  
Reza Shervin Badv ◽  
Mahmoud Mohammadi ◽  
Gholam Reza Zamani ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Ketogenic Diet ◽  
Repeated Measures ◽  
Intractable Epilepsy ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Significant Difference ◽  
Before And After

Abstract Objectives This study aimed to shed light on the differences between the effect of classical ketogenic diet (KD) and modified Atkins diet (MAD) on lipid profile in children and adolescents with intractable epilepsy. Methods The study was a non-randomized controlled clinical trial, conducted in the period of 2015 to 2017 (ClinicalTrials.gov, NCT03014752). Inclusion criteria included patients aged 1–18 years old, resistance to at least two antiepileptic drugs and no history of metabolic diseases that KD is contraindicated. The exclusion criteria included the occurrence of serious adverse effects and reluctance to adhere to the diet. Patients received the interventions for three months. Classical KD was initiated with 4:1 ketogenic ratio. MAD was initiated with a ketogenic ratio of 1:1 to 2:1 according to the John Hopkins protocol. The blood sample was obtained for measurement of the lipid profile, including triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein (HDL). A repeated measures ANOVA was performed to compare the differences between groups. Results Twenty-six patients were allocated to classical KD and 26 were allocated to MAD. Fourteen patients remained at the end of the study in each group. In the classical KD group, the serum levels of TC, TG and LDL increased significantly before and after three months. In the MAD group, the serum levels of TC and LDL increased significantly before and after the study. After three months, there was a significant difference in the serum levels of TG and LDL between classical KD and MAD groups (P < 0.05); however, no significant difference was observed in the serum levels of TC and HDL in both groups (P > 0.05). Conclusions Patients who were on the MAD had significantly higher levels of TG and LDL than those who were on classical KD. Funding Sources Tehran University of Medical Sciences.

scholarly journals Is Modified Atkins Diet Therapy Applicable for Adults with Intractable Epilepsy Patients? - A Short Trial in Adult Volunteers

2011 ◽  
Vol 4 (1) ◽  
pp. 7-14
Author(s):  
Miyako Oguni ◽  
Noriyo Inoue ◽  
Kyoya Takahata ◽  
Masamichi Koseki
Keyword(s):  
Intractable Epilepsy ◽  
Diet Therapy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Adult Volunteers

scholarly journals Will seizure control improve by switching from the modified Atkins diet to the traditional ketogenic diet?

Epilepsia ◽  
2010 ◽  
Vol 51 (12) ◽  
pp. 2496-2499 ◽  
Author(s):  
Eric H. Kossoff ◽  
Jennifer L. Bosarge ◽  
Maria J. Miranda ◽  
Adelheid Wiemer-Kruel ◽  
Hoon Chul Kang ◽  
...  
Keyword(s):  
Ketogenic Diet ◽  
Seizure Control ◽  
Modified Atkins Diet ◽  
Atkins Diet

scholarly journals Dietary therapy in childhood epilepsy, an overview

2014 ◽  
Vol 01 (01) ◽  
pp. 027-035 ◽  
Author(s):  
Sheffali Gulati ◽  
Biswaroop Chakrabarty
Keyword(s):  
Ketogenic Diet ◽  
Glycemic Index ◽  
Dietary Therapy ◽  
Childhood Epilepsy ◽  
Modified Atkins Diet ◽  
Atkins Diet ◽  
Systemic Side Effects ◽  
Low Glycemic Index Treatment ◽  
Index Treatment ◽  
Low Glycemic Index

AbstractThis review highlights the current consensus guidelines regarding use of dietary therapy in childhood epilepsy. Comprehensive search was done in the electronic database, journals, reference lists and dissertations related to the field. In childhood epilepsy, about one-third patients are medically refractory. Surgical resection is an effective modality only in a third of these cases. Dietary therapy causes upto 30–40% reduction in seizure frequency in drug refractory epilepsy. The various forms of dietary therapies described are ketogenic diet, modified Atkins diet and low glycemic index treatment. Apart from ketogenesis, the ketogenic diet also exerts its effect by modulating brain energetics and neurotransmitter circuitry. The classical ketogenic diet comprises of fat to carbohydrate ratio of 4:1 (in terms of weight in grams). Modified Atkins diet is restrictive only for carbohydrates (≤20 g per day). Low glycemic index treatment allows carbohydrate of upto 60 g per day with food items having glycemic index of less than 50. Consensus recommendations for indications and contraindications of dietary therapy in childhood epilepsy have been formulated. Moreover caution has to be warranted for various metabolic and systemic side effects described with this form of therapy. Laboratory and clinical assessment prior to initiation and periodically on therapy is recommended. A trial of dietary therapy is labeled as failure only if there is no response even after 12 weeks of therapy. There is research ongoing globally on dietary therapy with preliminary encouraging reports in status epilepticus and other neurological conditions like migraine, brain tumor and autism.

scholarly journals The Modified Atkins Diet in Refractory Epilepsy

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Suvasini Sharma ◽  
Puneet Jain
Keyword(s):  
Ketogenic Diet ◽  
Refractory Epilepsy ◽  
Outpatient Basis ◽  
Good Efficacy ◽  
Modified Atkins Diet ◽  
Atkins Diet

The modified Atkins diet is a less restrictive variation of the ketogenic diet. This diet is started on an outpatient basis without a fast, allows unlimited protein and fat, and does not restrict calories or fluids. Recent studies have shown good efficacy and tolerability of this diet in refractory epilepsy. In this review, we discuss the use of the modified Atkins diet in refractory epilepsy.

scholarly journals Ketogenic diet for epilepsy treatment

2016 ◽  
Vol 74 (10) ◽  
pp. 842-848 ◽  
Author(s):  
Letícia Pereira de Brito Sampaio
Keyword(s):  
Ketogenic Diet ◽  
Refractory Epilepsy ◽  
Medium Chain Triglyceride ◽  
Modified Atkins Diet ◽  
The Past ◽  
Atkins Diet ◽  
Low Carbohydrate ◽  
History Of ◽  
Index Treatment ◽  
Low Glycemic Index

ABSTRACT The ketogenic diet (KD), a high-fat, low-carbohydrate, and adequate-protein diet is an established, effective nonpharmacologic treatment option for intractable childhood epilepsy. The KD was developed in 1921 and even though it has been increasingly used worldwide in the past decade, many neurologists are not familiar with this therapeutic approach. In the past few years, alternative and more flexible KD variants have been developed to make the treatment easier and more palatable while reducing side effects and making it available to larger group of refractory epilepsy patients. This review summarizes the history of the KD and the principles and efficacy of the classic ketogenic diet, medium-chain triglyceride(s) (MCT) ketogenic diet, modified Atkins diet, and low glycemic index treatment.

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