Label-free and Dual-amplified Electrochemical Bioanalysis of MUC1 Based on an Inorganic-organic Polymer Hybrid Mimic Peroxidase (AuNPs@Cu7S4@Cu/Mn-AzoPPOP) and Catalytic Hairpin Assembly

2021 ◽  
pp. 130332
Author(s):  
Huijuan Zhao ◽  
Tingting Liu ◽  
Lin Cui ◽  
Yanhong Li ◽  
Fei Yang ◽  
...  
Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16149-16153 ◽  
Author(s):  
Chang Yeol Lee ◽  
Hyowon Jang ◽  
Ki Soo Park ◽  
Hyun Gyu Park

A target-triggered catalytic hairpin assembly with a G-quadruplex specific fluorescent binder, NMM, is employed to develop a novel and sensitive RNase H activity assay.


Polymers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2294
Author(s):  
Haw-Ming Huang ◽  
Er-Yuan Chuang ◽  
Fu-Lun Chen ◽  
Jia-De Lin ◽  
Yu-Cheng Hsiao

The highly sensitive interfacial effects between liquid crystal (LC) and alignment layers make LC-bioinspired sensors an important technology. However, LC-bioinspired sensors are limited by quantification requiring a polarized microscope and expensive equipment, which makes it difficult to commercialize LC-bioinspired sensors. In this report, we first demonstrate that dye-doped LC (DDLC) chips coated with vertically aligned layers can be employed as a new LC-bioinspired sensing technology. The DDLC-bioinspired sensor was tested by detecting bovine serum albumin (BSA) and immunocomplexes of BSA pairs. The intensities of the dye color of the DDLC-bioinspired sensor can be changed with the concentrations of biomolecules and immunocomplexes. A detection limit of 0.5 µg/mL was shown for the color-indicating DDLC-bioinspired sensors. We also designed a new method to use the quantitative DDLC-bioinspired sensor with a smart-phone for potential of home test. The novel DDLC-bioinspired sensor is cheap, label-free, and easy to use, furthering the technology for home and field-based disease-related detection.


2015 ◽  
Vol 31 (5) ◽  
pp. 807-816 ◽  
Author(s):  
KOU Yan-Lei ◽  
◽  
QU Sheng-Chun ◽  
LIU Kong ◽  
CHI Dan ◽  
...  

2000 ◽  
Vol 29 (11) ◽  
pp. 1310-1311 ◽  
Author(s):  
Atsushi Shimojima ◽  
Kazuyuki Kuroda

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