An efficient, label-free and sensitive electrochemical microRNA sensor based on target-initiated catalytic hairpin assembly of trivalent DNAzyme junctions

2020 ◽  
Vol 304 ◽  
pp. 127068 ◽  
Author(s):  
Ronghui Ren ◽  
Qian Bi ◽  
Ruo Yuan ◽  
Yun Xiang
Keyword(s):  
Label Free ◽  
Catalytic Hairpin Assembly

A label-free and enzyme-free signal amplification strategy for a sensitive RNase H activity assay

Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16149-16153 ◽  
Author(s):  
Chang Yeol Lee ◽  
Hyowon Jang ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Signal Amplification ◽  
Rnase H ◽  
Label Free ◽  
Activity Assay ◽  
G Quadruplex ◽  
Catalytic Hairpin Assembly ◽  
Amplification Strategy

A target-triggered catalytic hairpin assembly with a G-quadruplex specific fluorescent binder, NMM, is employed to develop a novel and sensitive RNase H activity assay.

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

2016 ◽  
Vol 52 (22) ◽  
pp. 4167-4170 ◽  
Author(s):  
Chia-Chen Chang ◽  
Chie-Pein Chen ◽  
Chen-Yu Chen ◽  
Chii-Wann Lin
Keyword(s):  
Gold Nanoparticle ◽  
Label Free ◽  
Colorimetric Sensing ◽  
Base Stacking ◽  
Nanoparticle Aggregation ◽  
Protein Sensing ◽  
Sensing Platform ◽  
Dna Base ◽  
Gold Nanoparticle Aggregation ◽  
Catalytic Hairpin Assembly

A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy.

Label-free and ratiometric detection of microRNA based on target-induced catalytic hairpin assembly and two fluorescent dyes

2019 ◽  
Vol 11 (37) ◽  
pp. 4808-4813 ◽  
Author(s):  
Danyang Ji ◽  
Xi Mou ◽  
Chun Kit Kwok
Keyword(s):  
Fluorescent Dyes ◽  
Detection Method ◽  
Label Free ◽  
Ratiometric Detection ◽  
Catalytic Hairpin Assembly

Based on target-induced catalytic hairpin assembly and two fluorescent dyes, we have developed a new label-free and ratiometric detection method for microRNAs.

scholarly journals Label-free impedimetric sensing platform for microRNA-21 based on ZrO2-reduced graphene oxide nanohybrids coupled with catalytic hairpin assembly amplification

RSC Advances ◽  
2018 ◽  
Vol 8 (29) ◽  
pp. 16146-16151 ◽  
Author(s):  
Keying Zhang ◽  
Na Zhang ◽  
Li Zhang ◽  
Hongyan Wang ◽  
Hongwei Shi ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Sensitive Detection ◽  
Label Free ◽  
Assembly Strategy ◽  
Sensing Platform ◽  
Reduced Graphene ◽  
Highly Sensitive ◽  
Catalytic Hairpin Assembly ◽  
Highly Sensitive Detection

A label-free impedimetric sensor for highly sensitive detection of miRNA-21 based on ZrO2-RGO nanocomposite and a catalytic hairpin assembly strategy.

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