Long-term remission of type 2 diabetes in morbidly obese patients after sleeve gastrectomy

Background. We investigated the effect of laparoscopic sleeve gastrectomy (LSG) on morbidly obese diabetics and examined the short-term impact of LSG on diabetic medication cost.Methods. A prospective database of consecutive bariatric patients was reviewed. Morbidly obese patients with type 2 diabetes who underwent LSG were included in the study. Age, gender, body mass index (BMI), diabetic medication use, glucose, insulin, and HbA1c levels were documented preoperatively, and at 2 weeks, 2 months, 6 months, and 12 months postoperatively. Insulin resistance was estimated using the homeostatic model assessment (HOMA). Use and cost of diabetic medications were followed.Results. Of 178 patients, 22 were diabetics who underwent LSG. Diabetes remission was observed in 62% of patients within 2 months and in 75% of patients within 12 months. HOMA-IR improved after only two weeks following surgery (16.5 versus 6.6, ). Average number of diabetic medications decreased from 2.2 to <1, within 2 weeks after surgery; corresponding to a diabetes medication cost savings of 80%, 91%, 99%, and 99.7% after 2 weeks, 2 months, 6 months, and 12 months, respectively.Conclusion. Morbidly obese patients with diabetes who undergo LSG have high rates of diabetes remission early after surgery. This translates to a significant medication cost savings.

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Is sleeve gastrectomy as effective as gastric bypass for remission of type 2 diabetes in morbidly obese patients?

Surgery for Obesity and Related Diseases ◽

10.1016/j.soard.2011.01.003 ◽

2011 ◽

Vol 7 (4) ◽

pp. 506-509 ◽

Cited By ~ 28

Author(s):

Amador García Ruiz de Gordejuela ◽

Jordi Pujol Gebelli ◽

Núria Vilarrasa García ◽

Enric Fernández Alsina ◽

Lluis Secanella Medayo ◽

...

Keyword(s):

Type 2 Diabetes ◽

Gastric Bypass ◽

Sleeve Gastrectomy ◽

Morbidly Obese ◽

Obese Patients

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Laparoscopic Sleeve Gastrectomy and Medical Management for the Treatment of Type 2 Diabetes Mellitus in Non-Morbidly Obese Patients: A Single-Center Experience

Diabetes Technology & Therapeutics ◽

10.1089/dia.2012.0308 ◽

2013 ◽

Vol 15 (4) ◽

pp. 281-288 ◽

Cited By ~ 10

Author(s):

Jacopo Desiderio ◽

Stefano Trastulli ◽

Vittorio Scalercio ◽

Roberto Cirocchi ◽

Giancarlo Carloni ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Sleeve Gastrectomy ◽

Medical Management ◽

Morbidly Obese ◽

Obese Patients ◽

Single Center ◽

Single Center Experience

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Sleeve gastrectomy with loop bipartition as a novel procedure for management of type 2 diabetes in obese patients

QJM ◽

10.1093/qjmed/hcaa050.010 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

R S Ezz ◽

M M Abouzeid ◽

M M Helmy ◽

M M Elhusseini

Keyword(s):

Type 2 Diabetes ◽

Sleeve Gastrectomy ◽

First Year ◽

Obese Patients ◽

Single Anastomosis ◽

Marked Weight

Abstract Background Amidst the current worldwide epidemic of type 2 diabetes mellitus (T2DM), the global diabetes health burden is projected to reach 522 million in 2030, with much of this increase occurring in developing countries. Aim of the work to evaluate the role of laparoscopic sleeve gastrectomy with loop bipartition (single anastomosis sleeve ileal bypass) as a bariatric and metabolic procedure in control of type 2 diabetes in obese patients. Patients and methods This prospective cohort study included 20 obese adult patients with type 2 DM recently diagnosed within last 5 years. Some of them have other associated comorbidities. They were recruited at department of surgery Ain Shams University. The follow up was obtained during the first year post-operative. Results In this study, complete remission of diabetes was achieved in 75% of the patients by the 3rd post-operative month and in 95% by the end of the study. This was beside marked weight reduction and improvement of lipid profile without causing micronutrients deficiencies during the study period. Conclusion SASI bypass can be one of the most efficient metabolic procedures and could be associated with less risks. The procedure should be considered under investigations until enough long term data are available. Thus it is worth to be explored in research aiming for more data.

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