Precipitation of β-carotene and PHBV and co-precipitation from SEDS technique using supercritical CO2

2008 ◽  
Vol 47 (2) ◽  
pp. 259-269 ◽  
Author(s):  
Elton Franceschi ◽  
Alana M. De Cesaro ◽  
Mirian Feiten ◽  
Sandra R.S. Ferreira ◽  
Cláudio Dariva ◽  
...  
2010 ◽  
Vol 99 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Marleny D.A. Saldaña ◽  
Feral Temelli ◽  
Selma E. Guigard ◽  
Bruno Tomberli ◽  
Chris G. Gray

2003 ◽  
Vol 42 (25) ◽  
pp. 6641-6646 ◽  
Author(s):  
E. Sabio ◽  
M. Lozano ◽  
V. Montero de Espinosa ◽  
R. L. Mendes ◽  
A. P. Pereira ◽  
...  

2014 ◽  
Vol 59 (3) ◽  
pp. 653-658 ◽  
Author(s):  
Darija Cör ◽  
Mojca Škerget ◽  
Željko Knez

2018 ◽  
Vol 138 ◽  
pp. 124-131 ◽  
Author(s):  
Maiko Ono ◽  
Masaki Honda ◽  
Wahyudiono ◽  
Keiji Yasuda ◽  
Hideki Kanda ◽  
...  

2001 ◽  
Vol 21 (3) ◽  
pp. 195-203 ◽  
Author(s):  
Helena Sovová ◽  
Roumiana P. Stateva ◽  
Anatolii A. Galushko

2007 ◽  
Vol 342-343 ◽  
pp. 477-480
Author(s):  
Xi Ming Pu ◽  
Yun Qing Kang ◽  
Ai Zheng Chen ◽  
Li Liao ◽  
Guang Fu Yin

5-Fluorouracil-poly(L-lactide) (5-Fu-PLLA) microspheres have been co-precipitated in a process namely solution-enhanced dispersion by supercritical CO2 (SEDS). First, the 5-Fu is successfully micronized and then used to produce the 5-Fu-PLLA microspheres. The 5-Fu-PLLA microspheres synthesized in the SEDS process exhibited a rather spherical shape, smooth surface, and a narrow particle size distribution, where it ranged from 531 nm to 1280 nm, with a mean particle size of 793 nm. The dichloromethane residue in the 5-Fu-PLLA microspheres is 46 ppm. The average drug load of the 5-Fu-PLLA microspheres is 12.7%. The results of this study indicate that the SEDS process is an effective technique to co-precipitate 5-Fu and PLLA as composite microspheres.


2009 ◽  
Vol 95 (4) ◽  
pp. 656-663 ◽  
Author(s):  
E. Franceschi ◽  
A.M. De Cesaro ◽  
S.R.S. Ferreira ◽  
J. Vladimir Oliveira

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