Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats

Beshay N.M. Zordoky; Anwar Anwar-Mohamed; Mona E. Aboutabl; Ayman O.S. El-Kadi

doi:10.1016/j.taap.2009.09.012

Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2009.09.012 ◽

2010 ◽

Vol 242 (1) ◽

pp. 38-46 ◽

Cited By ~ 69

Author(s):

Beshay N.M. Zordoky ◽

Anwar Anwar-Mohamed ◽

Mona E. Aboutabl ◽

Ayman O.S. El-Kadi

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism ◽

P450 Expression ◽

Doxorubicin Cardiotoxicity

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Faculty Opinions recommendation of Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10961956.11897054 ◽

2011 ◽

Author(s):

John Imig

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Rat Kidney ◽

Arachidonic Acid Metabolism ◽

Doxorubicin Toxicity ◽

P450 Expression

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Chronic Doxorubicin Cardiotoxicity Modulates Cardiac Cytochrome P450-Mediated Arachidonic Acid Metabolism in Rats

Drug Metabolism and Disposition ◽

10.1124/dmd.112.046631 ◽

2012 ◽

Vol 40 (11) ◽

pp. 2126-2135 ◽

Cited By ~ 29

Author(s):

Abdulaziz M. S. Alsaad ◽

Beshay N. M. Zordoky ◽

Ahmed A. El-Sherbeni ◽

Ayman O. S. El-Kadi

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism ◽

Doxorubicin Cardiotoxicity

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Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

Xenobiotica ◽

10.3109/00498254.2012.754113 ◽

2013 ◽

Vol 43 (8) ◽

pp. 719-729 ◽

Cited By ~ 12

Author(s):

Anwar Anwar-Mohamed ◽

Ahmed El-Sherbeni ◽

Seok Hee Kim ◽

Osama H. Elshenawy ◽

Hassan N. Althurwi ◽

...

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism ◽

P450 Expression ◽

Liver And Kidney

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Acute Doxorubicin Toxicity Differentially Alters Cytochrome P450 Expression and Arachidonic Acid Metabolism in Rat Kidney and Liver

Drug Metabolism and Disposition ◽

10.1124/dmd.111.039123 ◽

2011 ◽

Vol 39 (8) ◽

pp. 1440-1450 ◽

Cited By ~ 51

Author(s):

Beshay N. M. Zordoky ◽

Anwar Anwar-Mohamed ◽

Mona E. Aboutabl ◽

Ayman O. S. El-Kadi

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Rat Kidney ◽

Arachidonic Acid Metabolism ◽

Doxorubicin Toxicity ◽

P450 Expression

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Modulation of Cytochrome P450 Gene Expression and Arachidonic Acid Metabolism during Isoproterenol-Induced Cardiac Hypertrophy in Rats

Drug Metabolism and Disposition ◽

10.1124/dmd.108.023077 ◽

2008 ◽

Vol 36 (11) ◽

pp. 2277-2286 ◽

Cited By ~ 68

Author(s):

Beshay N. M. Zordoky ◽

Mona E. Aboutabl ◽

Ayman O. S. El-Kadi

Keyword(s):

Gene Expression ◽

Arachidonic Acid ◽

Cytochrome P450 ◽

Cardiac Hypertrophy ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism ◽

Cytochrome P450 Gene ◽

P450 Gene

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Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart

Xenobiotica ◽

10.3109/00498254.2012.693971 ◽

2012 ◽

Vol 42 (12) ◽

pp. 1235-1247 ◽

Cited By ~ 19

Author(s):

Anwar Anwar-Mohamed ◽

Ahmed A. El-Sherbeni ◽

Seok H. Kim ◽

Hassan N. Althurwi ◽

Beshay N. M. Zordoky ◽

...

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Epoxide Hydrolase ◽

Acid Metabolism ◽

Soluble Epoxide Hydrolase ◽

Arachidonic Acid Metabolism ◽

Mouse Heart ◽

Arsenic Toxicity

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Differential induction of cytochromes P450 and cytochrome P450-dependent arachidonic acid metabolism by 3,4,5,3′,4′-pentachlorobiphenyl in the rat and the guinea pig

Toxicology and Applied Pharmacology ◽

10.1016/0041-008x(91)90271-f ◽

1991 ◽

Vol 108 (1) ◽

pp. 86-95 ◽

Cited By ~ 25

Author(s):

Shewen Huang ◽

G.Gordon Gibson

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Guinea Pig ◽

Acid Metabolism ◽

Cytochromes P450 ◽

Arachidonic Acid Metabolism ◽

Differential Induction

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Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases

Pharmacology & Therapeutics ◽

10.1016/j.pharmthera.2009.12.002 ◽

2010 ◽

Vol 125 (3) ◽

pp. 446-463 ◽

Cited By ~ 123

Author(s):

Beshay N.M. Zordoky ◽

Ayman O.S. El-Kadi

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Cardiovascular Diseases ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism

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Cytochrome P450-dependent arachidonic acid metabolism in human kidney

Kidney International ◽

10.1038/ki.1990.13 ◽

1990 ◽

Vol 37 (1) ◽

pp. 94-99 ◽

Cited By ~ 71

Author(s):

Michal L. Schwartzman ◽

Pavel Martasek ◽

Amelia R. Rios ◽

Richard D. Levere ◽

Karim Solangi ◽

...

Keyword(s):

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Human Kidney ◽

Arachidonic Acid Metabolism

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3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2009.00461.x ◽

2009 ◽

Vol 158 (7) ◽

pp. 1808-1819 ◽

Cited By ~ 46

Author(s):

Mona E Aboutabl ◽

Beshay NM Zordoky ◽

Ayman OS El-Kadi

Keyword(s):

Gene Expression ◽

Arachidonic Acid ◽

Cytochrome P450 ◽

Acid Metabolism ◽

Arachidonic Acid Metabolism ◽

Sprague Dawley ◽

Cytochrome P450 Gene ◽

P450 Gene ◽

Sprague Dawley Rats

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