Inhibition of NLRP3 inflammasome activation in myeloid-derived suppressor cells by andrographolide sulfonate contributes to 5-FU sensitization in mice

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2021.115672 ◽

2021 ◽

pp. 115672

Author(s):

Lingyan Xu ◽

Peifen Cai ◽

Xiaofei Li ◽

Xiaohan Wu ◽

Jian Gao ◽

...

Keyword(s):

Nlrp3 Inflammasome ◽

Suppressor Cells ◽

Inflammasome Activation ◽

Myeloid Derived Suppressor Cells ◽

Nlrp3 Inflammasome Activation

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248-LB: Deficiency of APPL1 in Macrophages Triggers Adipose Tissue Inflammation and Insulin Resistance by Potentiating NLRP3 Inflammasome Activation

Diabetes ◽

10.2337/db19-248-lb ◽

2019 ◽

Vol 68 (Supplement 1) ◽

pp. 248-LB ◽

Author(s):

KELVIN K.L. WU ◽

AIMIN XU ◽

KENNETH K. CHENG

Keyword(s):

Insulin Resistance ◽

Adipose Tissue ◽

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Adipose Tissue Inflammation ◽

Tissue Inflammation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717968003.793467654 ◽

2012 ◽

Author(s):

Francesco Di Virgilio

Keyword(s):

Tumor Growth ◽

Nlrp3 Inflammasome ◽

Cathepsin B ◽

Suppressor Cells ◽

Myeloid Derived Suppressor Cells

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Faculty Opinions recommendation of Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717980435.793471692 ◽

2013 ◽

Author(s):

Laurel Lenz ◽

Rebecca Schmidt

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718039111.793480657 ◽

2013 ◽

Author(s):

Douglas Green ◽

Jennifer Martinez

Keyword(s):

Fatty Acids ◽

Nlrp3 Inflammasome ◽

Metabolic Disorder ◽

Inflammasome Activation ◽

Omega 3 Fatty Acids ◽

Omega 3 ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of 3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718184539.793519737 ◽

2016 ◽

Author(s):

Eicke Latz

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726362863.793559823 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Dextran Sulfate ◽

Dextran Sulfate Sodium ◽

Experimental Colitis ◽

Dimethyl Fumarate ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Hemin and cobalt protoporphyrin inhibit NLRP3 inflammasome activation by enhancing autophagy: A novel mechanism of inflammasome regulation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726766143.793523875 ◽

2016 ◽

Author(s):

Mark A Williams

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation ◽

Cobalt Protoporphyrin

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Faculty Opinions recommendation of Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734279765.793559839 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734514948.793559815 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Trans Golgi Network ◽

Nlrp3 Inflammasome Activation ◽

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Faculty Opinions recommendation of The role of lysosomal cysteine cathepsins in NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.735165969.793559816 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Cysteine Cathepsins ◽

Nlrp3 Inflammasome Activation

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