Expedient one-step synthesis of nitrogen stilbene analogs by transition metal-free hydroamination of arylacetylenes with pyrroles

Tetrahedron ◽  
2012 ◽  
Vol 68 (7) ◽  
pp. 1963-1971 ◽  
Author(s):  
Marina Yu. Dvorko ◽  
Elena Yu. Schmidt ◽  
Tatyana E. Glotova ◽  
Dmitrii A. Shabalin ◽  
Igor' A. Ushakov ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
One Step ◽  
Stilbene Analogs

Synthesis of 1,4-diazepinone derivatives via a domino aza-Michael/SN2 cyclization of 1-azadienes with α-halogenoacetamides

2020 ◽  
Vol 18 (6) ◽  
pp. 1082-1086 ◽  
Author(s):  
Chunhao Yuan ◽  
Hui Zhang ◽  
Mengna Yuan ◽  
Lei Xie ◽  
Xiaoqun Cao
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
One Step

A novel cyclization of N-alkoxy α-halogenoacetamides with N-sulfonyl-1-aza-1,3-butadienes has been developed for the efficient preparation of 1,4-diazepinones in one step under transition metal-free conditions.

scholarly journals Easy Access To Allylic Sulfones Through Transition Metal-Free Hydrosulfonylation Of Allenes

2021 ◽  
Author(s):  
Lucas Pages ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Transition Metal ◽  
Good Yield ◽  
Easy Access ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Metal Free ◽  
Brönsted Acid ◽  
One Step

A Brønsted acid-mediated addition of (hetero)aryl and (cyclo)alkyl sodium sulfinates to <i>N</i>-allenyl derivatives is described under very smooth conditions. This reaction provided a practical and efficient protocol for the synthesis of allylic sulfones in an atom- and step-economic fashion. In addition, an one-step double hydrosulfonylation has also been demonstrated, affording the corresponding 1,3-disulfone in to good yield.<br>

scholarly journals Single-step Syznthesis of Coenzyme Q0

2019 ◽  
pp. 1-4
Author(s):  
Yi-Yu Yan ◽  
Yong-Fu Qiu ◽  
Tian-Li Zhang ◽  
Yu-Bei He ◽  
Shi Qi ◽  
...  
Keyword(s):  
Transition Metal ◽  
Ammonium Persulfate ◽  
Single Step ◽  
New Method ◽  
Metal Free ◽  
One Step ◽  
Coenzyme Q0

A new method for the preparation of 2-methyl-5,6-dimethoxy-1,4-benzoquinone (Coenzyme Q0) was developed. This improved process in one step by the oxidation of 3,4,5-trimethoxytoluene to coenzyme Q0 by simple oxidation using potassium or ammonium persulfate under transition -metal free conditions.

Transition-Metal-Free One-Step Synthesis of Ynamides

2019 ◽  
Vol 84 (7) ◽  
pp. 4458-4466 ◽  
Author(s):  
Xianzhu Zeng ◽  
Yongliang Tu ◽  
Zhenming Zhang ◽  
Changming You ◽  
Jiao Wu ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
One Step

Transition-metal-free cross-coupling of thioethers with aryl(cyano)iodonium triflates: a facile and efficient method for the one-pot synthesis of thiocyanates

2015 ◽  
Vol 51 (33) ◽  
pp. 7180-7183 ◽  
Author(s):  
Dan Zhu ◽  
Denghu Chang ◽  
Lei Shi
Keyword(s):  
Transition Metal ◽  
Efficient Method ◽  
Bond Cleavage ◽  
Cross Coupling ◽  
One Pot ◽  
Metal Free ◽  
One Pot Synthesis ◽  
One Step ◽  
The One

A novel transition-metal-free method for the one-step synthesis of thiocyanates via the C–S bond cleavage of readily available thioethers was developed.

ChemInform Abstract: Expedient One-Step Synthesis of Nitrogen Stilbene Analogues by Transition Metal-Free Hydroamination of Arylacetylenes with Pyrroles.

ChemInform ◽  
2012 ◽  
Vol 43 (27) ◽  
pp. no-no
Author(s):  
Marina Yu. Dvorko ◽  
Elena Yu. Schmidt ◽  
Tatyana E. Glotova ◽  
Dmitrii A. Shabalin ◽  
Igor' A. Ushakov ◽  
...  
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
One Step ◽  
Stilbene Analogues

Sulfite-Promoted C–H Fluoroalkyl Sulfuration of Imidazoheterocycles with Bromofluoroacetate and Elemental Sulfur

Synthesis ◽  
2020 ◽  
Vol 52 (17) ◽  
pp. 2541-2550
Author(s):  
Zi-Ning Cui ◽  
Ri-Yuan Tang ◽  
Yong-Chao Gao ◽  
Zi-Hao Huang ◽  
Zhao-Sheng Zhang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Elemental Sulfur ◽  
Metal Free ◽  
One Step ◽  
Component C

A transition-metal-free sulfite-promoted three-component C–H sulfuration between imidazoheterocycles, elemental sulfur, and bromofluoroacetate is developed. Sulfites, including Na2S2O4, NaHSO3, and Na2S2O3, are able to promote the formation of two C–S bonds in one step using elemental sulfur as a green sulfurating agent, allowing the rapid introduction of the synthetically useful S-fluoroacetate group into imidazoheterocycles. These new imidazoheterocycle derivatives bearing an S-fluoroacetate group can be easily modified to produce pharmaceutically attractive compounds.

Transition-metal-free, base-promoted annulation/ring-cleavage/ring-reconstruction cascades: a facile access to N-protection free indole-indenones

2021 ◽  
Author(s):  
Na Luo ◽  
Zhen-Wei Sun ◽  
Xing-Xin Xu ◽  
Xiao-Qiang Hu ◽  
Feng-Cheng Jia
Keyword(s):  
Transition Metal ◽  
Cascade Reaction ◽  
Ring Cleavage ◽  
Free Base ◽  
Metal Free ◽  
One Step ◽  
Step Transition ◽  
Straightforward Approach

A one-step, transition-metal-free, base-promoted cascade reaction of 2-halogenated arylglyoxals with 2-oxindoles is reported herein, which provides a straightforward approach to structurally diverse free (NH)-indeno[2,1-b]indol-6(5H)-ones in satisfactory yields. Control experiments indicated...

scholarly journals Easy Access To Allylic Sulfones Through Transition Metal-Free Hydrosulfonylation Of Allenes

2021 ◽  
Author(s):  
Lucas Pages ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Transition Metal ◽  
Good Yield ◽  
Easy Access ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Metal Free ◽  
Brönsted Acid ◽  
One Step

A Brønsted acid-mediated addition of (hetero)aryl and (cyclo)alkyl sodium sulfinates to <i>N</i>-allenyl derivatives is described under very smooth conditions. This reaction provided a practical and efficient protocol for the synthesis of allylic sulfones in an atom- and step-economic fashion. In addition, an one-step double hydrosulfonylation has also been demonstrated, affording the corresponding 1,3-disulfone in to good yield.<br>

Transition-metal-free catalytic hydroboration reduction of amides to amines

2020 ◽  
Vol 7 (21) ◽  
pp. 3515-3520
Author(s):  
Wubing Yao ◽  
Jiali Wang ◽  
Aiguo Zhong ◽  
Shiliang Wang ◽  
Yinlin Shao
Keyword(s):  
Transition Metal ◽  
Selective Catalytic Reduction ◽  
Catalytic Reduction ◽  
Value Added ◽  
Metal Free

The selective catalytic reduction of amides to value-added amine products is a desirable but challenging transformation.

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