Spectroscopic analyses and chemical transformation for structure elucidation of two novel indole alkaloids from Gelsemium elegans

Two new indole alkaloids, kopsiyunnanines J1 and J2, were isolated from Yunnan Kopsia arborea, and their structures were determined by spectroscopic analyses. Kopsiyunnanines J1 and J2 are unprecedented Strychnos-type indole alkaloids having an additional C1 unit in the secologanin moiety of the molecule.

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Dithiosulfinates and Sulfoxides with Antifungal Activity from Bulbs of Allium sativum L. var. Voghiera

Natural Product Communications ◽

10.1177/1934578x1801300916 ◽

2018 ◽

Vol 13 (9) ◽

pp. 1934578X1801300

Author(s):

Bruna de Falco ◽

Giuliano Bonanomi ◽

Virginia Lanzotti

Keyword(s):

Antimicrobial Activity ◽

Nmr Spectroscopy ◽

Antifungal Activity ◽

Botrytis Cinerea ◽

Trichoderma Harzianum ◽

Structure Elucidation ◽

Allium Sativum ◽

Fungal Species ◽

Phytochemical Analysis ◽

Spectroscopic Analyses

A bioassay guided phytochemical analysis of the bulbs of Allium sativum L. var. Voghiera, typical of Voghiera, Ferrara (Italy), allowed the isolation of six new sulfur compounds with dithiosulfinates and sulfoxides functionalities. Structure elucidation of the isolated compounds was carried out by spectroscopic analyses, including NMR spectroscopy and MS spectrometry. Compounds showed significant antimicrobial activity towards two fungal species, the air-borne pathogen Botrytis cinerea and the beneficial fungus Trichoderma harzianum.

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Studies on the indole alkaloids of gelsem1um elegans (thailand): structure elucidation and proposal of biogenetic route

Tetrahedron ◽

10.1016/s0040-4020(01)86012-9 ◽

1988 ◽

Vol 44 (16) ◽

pp. 5075-5094 ◽

Cited By ~ 61

Author(s):

Dhavadee Ponglux ◽

Sumphan Wongseripipatana ◽

Sanan Subhadhirasakul ◽

Hiromitsu Takayama ◽

Masaki Yokota ◽

...

Keyword(s):

Structure Elucidation ◽

Indole Alkaloids

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ChemInform Abstract: Indole Alkaloids of Gelsemium elegans (Thailand): Structure Elucidation and Proposal of Biogenetic Route.

ChemInform ◽

10.1002/chin.198901263 ◽

1989 ◽

Vol 20 (1) ◽

Author(s):

D. PONGLUX ◽

S. WONGSERIPIPATANA ◽

S. SUBHADHIRASAKUL ◽

H. TAKAYAMA ◽

M. YOKOTA ◽

...

Keyword(s):

Structure Elucidation ◽

Indole Alkaloids

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Isolation and Structure Elucidation of Tyramine and Indole Alkaloids from Antarctic StrainMicrobispora AerataIMBAS-11A

Biotechnology & Biotechnological Equipment ◽

10.1080/13102818.2003.10817070 ◽

2003 ◽

Vol 17 (2) ◽

pp. 128-133 ◽

Cited By ~ 7

Author(s):

V. Ivanova ◽

U. Graefe ◽

R. Schlegel ◽

B. Schlegel ◽

A. Gusterova ◽

...

Keyword(s):

Structure Elucidation ◽

Indole Alkaloids

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Barakacin: A Thiazolyl-indole Alkaloid Isolated from a Ruminal Pseudomonas sp.

Zeitschrift für Naturforschung B ◽

10.5560/znb.2011-0277 ◽

2012 ◽

Vol 67 (5) ◽

pp. 417-420 ◽

Cited By ~ 11

Author(s):

Imene Zendah ◽

Khaled A. Shaaban ◽

Elisabeth Helmke ◽

Armin Maier ◽

Heinz H. Fiebig ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

Carboxylic Acid ◽

Structure Elucidation ◽

Biological Activities ◽

Indole Alkaloid ◽

Ecological Niches ◽

Pseudomonas Sp ◽

Ruminal Bacterium ◽

Spectroscopic Analyses ◽

Related Compounds

A new thiazolyl-indole alkaloid, barakacin (1), has been isolated from the ruminal bacterium Pseudomonas aeruginosa strain ZIO. On the basis of detailed spectroscopic analyses and comparison with the data of related compounds, its structure has been determined as 2-{4-[bis-(1H-indol-3- yl)-methyl]-thiazol-2-yl}-phenol. In addition, the known compounds phenazine-1-carboxylic acid, 3-(hydroxyacetyl)-indole, indole-3-carbaldehyde, and glycolipid A were isolated. The discovery of compounds with a new skeleton emphasizes the importance for exploring new ecological niches like the rumen of bovines for the detection of new natural products. This paper describes the fermentation, isolation, structure elucidation and biological activities of compound 1.

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