Palladium-catalyzed carbonylative coupling of benzyl chlorides with aryl boronic acids in aqueous media

2010 ◽  
Vol 51 (47) ◽  
pp. 6146-6149 ◽  
Author(s):  
Xiao-Feng Wu ◽  
Helfried Neumann ◽  
Matthias Beller
Keyword(s):  
Aqueous Media ◽  
Boronic Acids ◽  
Benzyl Chlorides ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Aminocarbonylation of Benzyl Chlorides Using Ammonia.

ChemInform ◽  
2012 ◽  
Vol 43 (21) ◽  
pp. no-no
Author(s):  
Xiao-Feng Wu ◽  
Johannes Schranck ◽  
Helfried Neumann ◽  
Matthias Beller
Keyword(s):  
Benzyl Chlorides ◽  
Palladium Catalyzed

Palladium-Catalyzed Carbonylative Cyclization of Benzyl Chlorides with Anthranils for the Synthesis of 3-Arylquinolin-2(1H)-ones

2021 ◽  
Author(s):  
Xiao-Feng Wu ◽  
Ren-Rui Xu ◽  
wei wang ◽  
Jian-Li Liu ◽  
Xinxin Qi
Keyword(s):  
Benzyl Chlorides ◽  
Palladium Catalyzed

An efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1H)-ones has been established. Through a palladium-catalyzed aminocarbonylation of benzyl chlorides with anthranils, a variety of 3-arylquinoin-2(1H)-one products were obtained in moderate...

Synthesis of Indole/Benzofuran-Containing Diarylmethanes through Palladium-Catalyzed Reaction of Indolylmethyl or Benzofuranylmethyl Acetates with Boronic Acids

Synthesis ◽  
2021 ◽  
Author(s):  
Antonella Goggiamani ◽  
Antonia Iazzetti ◽  
Antonio Arcadi ◽  
Andrea Calcaterra ◽  
Marco Chiarini ◽  
...  
Keyword(s):  
Boronic Acids ◽  
Experimental Procedure ◽  
Palladium Catalyzed ◽  
High Yields ◽  
Reaction Works

AbstractThe palladium-catalyzed synthesis of indole/benzofuran-containing diarylmethanes starting from indolylmethyl or benzofuranylmethyl acetates with boronic acids has been investigated. The success of the reaction is influenced by the choice of precatalyst: with indolylmethyl acetates the reaction works well with [Pd(η3-C3H5)Cl]2/XPhos while with benzofuranylmethyl acetates Pd2(dba)3/XPhos is more efficient. The good to high yields and the simplicity of the experimental procedure make this protocol a versatile synthetic tool for the preparation of 2- and 3-substituted indoles and 2-benzo[b]furans. The methodology can be advantageously extended to the preparation of a key precursor of Zafirlukast.

ChemInform Abstract: Palladium-Catalyzed Direct Amination of Allylic Alcohols in Aqueous Media.

ChemInform ◽  
2016 ◽  
Vol 47 (43) ◽  
Author(s):  
Zhengyin Du ◽  
Yufei Yan ◽  
Ying Fu ◽  
Kehu Wang
Keyword(s):  
Aqueous Media ◽  
Allylic Alcohols ◽  
Direct Amination ◽  
Palladium Catalyzed
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