Domino reaction of arylamine, methyl propiolate, aromatic aldehyde, and indole for facile synthesis of functionalized indol-3-yl acrylates

In the presence of p-toluenesulfonic acid as catalyst the domino reaction of arylamines, methyl propiolates and aromatic aldehydes in ethanol proceeded smoothly to give polysubstituted 1,2,3,4-tetrahydroquinolines in moderate yields. The reaction is believed to involve the Povarov reaction of in situ generated β-enamino ester with the in situ formed aromatic imine.

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A facile synthesis of tetracyclic benzo-pyridonaphthyridines by domino reaction

Tetrahedron Letters ◽

10.1016/j.tetlet.2013.02.016 ◽

2013 ◽

Vol 54 (15) ◽

pp. 2014-2017 ◽

Cited By ~ 4

Author(s):

Vishnu Basetti ◽

Rangarao Pallepati ◽

Subramanya Hosahalli ◽

Vijay Potluri

Keyword(s):

Domino Reaction ◽

Facile Synthesis

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Facile synthesis of annulated heterocyclic benzo[kl]acridine derivatives via one-pot N–H/C–H coupling

Organic Chemistry Frontiers ◽

10.1039/c6qo00371k ◽

2016 ◽

Vol 3 (11) ◽

pp. 1520-1523 ◽

Cited By ~ 1

Author(s):

Yulian Zagranyarski ◽

Artem Skabeev ◽

Yingjie Ma ◽

Klaus Müllen ◽

Chen Li

Keyword(s):

Domino Reaction ◽

Efficient Synthesis ◽

Facile Synthesis ◽

One Pot ◽

Acridine Derivatives

A facile and efficient synthesis of benzo[kl]acridines was developed based on a domino reaction via a combinatorial catalyst approach.

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The UiO-66-SO3H metal–organic framework as a green catalyst for the facile synthesis of dihydro-2-oxypyrrole derivatives

RSC Advances ◽

10.1039/c6ra00463f ◽

2016 ◽

Vol 6 (35) ◽

pp. 29182-29189 ◽

Cited By ~ 30

Author(s):

Ramin Ghorbani-Vaghei ◽

Davood Azarifar Davood Azarifar ◽

Saba Daliran ◽

Ali Reza Oveisi

Keyword(s):

Metal Organic Framework ◽

Acid Catalyst ◽

Domino Reaction ◽

Reaction Synthesis ◽

Facile Synthesis ◽

Green Catalyst ◽

Metal Organic ◽

University Of Oslo ◽

The University ◽

Organic Framework

The multicomponent domino reaction synthesis of dihydro-2-oxopyrroles has been performed using the sulfonated metal–organic framework, UiO-66-SO3H (UiO is the University of Oslo), as a highly efficient acid catalyst.

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Phosphine-catalyzed [4 + 2] annulation of γ-benzyl allenoates: facile synthesis of benzothieno[3,2-b]pyran derivatives

Organic & Biomolecular Chemistry ◽

10.1039/c8ob00004b ◽

2018 ◽

Vol 16 (16) ◽

pp. 2885-2892 ◽

Cited By ~ 10

Author(s):

Shanshan Ma ◽

Aimin Yu ◽

Xiangtai Meng

Keyword(s):

Domino Reaction ◽

Facile Synthesis ◽

High Yields

An efficient tris(4-methoxyphenyl)phosphane catalyzed domino reaction between γ-benzyl allenoate and ethyl (Z)-2-(3-oxobenzo[b]thiophen-2(3H)-ylidene)acetate has been developed, which produces a series of 2H-benzo[4,5]thieno[3,2-b]pyran derivatives in high yields.

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