Facile synthesis of functionalized tetrahydroquinolines via domino Povarov reactions of arylamines, methyl propiolate and aromatic aldehydes
2012 ◽
Vol 8
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pp. 1839-1843
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Keyword(s):
In the presence of p-toluenesulfonic acid as catalyst the domino reaction of arylamines, methyl propiolates and aromatic aldehydes in ethanol proceeded smoothly to give polysubstituted 1,2,3,4-tetrahydroquinolines in moderate yields. The reaction is believed to involve the Povarov reaction of in situ generated β-enamino ester with the in situ formed aromatic imine.
2016 ◽
Vol 14
(41)
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pp. 9720-9724
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2012 ◽
Vol 53
(51)
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pp. 6965-6967
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2005 ◽
Vol 15
(6)
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pp. 955-960
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Keyword(s):
Keyword(s):
2019 ◽
Vol 32
◽
pp. 78-84
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Keyword(s):