C0258 Importance of the effect of aspirin in patients with acute coronary syndrome who have an adequate antiplatelet effect of clopidogrel

2012 ◽  
Vol 130 ◽  
pp. S127
Author(s):  
Juana Valles ◽  
Isabel Madrid ◽  
Antonio Moscardo ◽  
Juan Bonastre ◽  
Miguel Ruano ◽  
...  
2015 ◽  
Vol 3 (3) ◽  
pp. 117-124
Author(s):  
Michał Kasprzak ◽  
Małgorzata Molska ◽  
Karolina Obońska ◽  
Emilia Kolasińska ◽  
Julia Maria Kubica ◽  
...  

2017 ◽  
Vol 68 (11) ◽  
pp. 2726-2730
Author(s):  
Irina Iuliana Costache ◽  
Florin Mitu ◽  
Razan Al Namat ◽  
Iuliu Ivanov ◽  
Roxana Popescu ◽  
...  

The antiplatelet effect of clopidogrel prodrug is characterized by a wide inter-individual variability that has a significant clinical relevance. Among varios factors that are involved in the occurrence of clopidogrel resistance, the genetic polymorphisms play a key role. The aim of the present study was to investigate the impact of some risk factors for atherosclerosis on the antiplatelet effect of clopidogrel in patients with acute coronary syndrome and the possible correlation with metabolizer phenotype of patients based on CYP2C19 polymorfisms. We found a statistically significant correlation (p value [ 0.05) between smoking or dyslipidaemia and the presence of ultrarapid metabolizer phenotype for clopidogrel in our research population.


2017 ◽  
Vol 32 (12) ◽  
pp. 1432-1438
Author(s):  
Erito Furuse ◽  
Hitoshi Takano ◽  
Takeshi Yamamoto ◽  
Yoshiaki Kubota ◽  
Takashi Yoshizane ◽  
...  

2016 ◽  
Vol 22 ◽  
pp. 121-122
Author(s):  
Mukhyaprana Prabhu ◽  
Shyny Reddy ◽  
Ranjan Shetty ◽  
V.B. Mohan ◽  
Weena Stanley

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