Delayed Graft Function and Long-Term Outcome in Kidney Transplantation

2012 ◽  
Vol 44 (7) ◽  
pp. 1879-1883 ◽  
Author(s):  
G. Grosso ◽  
D. Corona ◽  
A. Mistretta ◽  
D. Zerbo ◽  
N. Sinagra ◽  
...  

2019 ◽  
Author(s):  
Xiao-jun Hu ◽  
Jin Zheng ◽  
Yang Li ◽  
Xiao-hui Tian ◽  
Pu-xun Tian ◽  
...  

Abstract Background Delayed graft function (DGF) is an important complication of kidney transplantation and can be diagnosed according to different definitions. DGF has been proven to be associated with the long-term outcome of kidney transplantation surgery. However, the best DGF definition for predicting renal transplant outcomes in Chinese donations after cardiac death (DCDs) remains to be determined. Method A total of 182 DCD kidney transplants from January 2015 to December 2015 in the First Affiliated Hospital of Xi’an Jiaotong University were diagnosed with DGF according to 6 different DGF definitions. The relationship of the DGF definitions to the three-year graft loss (GL) and 12-month estimated glomerular filtration rate (eGFR) posttransplantation was compared. Results The incidence of DGF varied from 5.01% to 50.89% according to the different DGF diagnoses. All DGF definitions were significantly associated with three-year GL and had considerable predictive power for a poorer transplant outcome. None of the DGF definitions were significantly better than the dialysis-based DGF definition. Conclusion DGF was a independent risk factor for poorer transplant outcome. In the Chinese DCD population, no definitions were superior to the universally accepted one, namely, the need for hemodialysis in the first week posttransplantation. Combination of need for hemodialysis within the first week and 48h serum creatinine reduction rate has a better predictive value for graft loss.



2013 ◽  
Vol 84 (6) ◽  
pp. 1214-1225 ◽  
Author(s):  
Matthew P. Welberry Smith ◽  
Alexandre Zougman ◽  
David A. Cairns ◽  
Michelle Wilson ◽  
Tobias Wind ◽  
...  




2012 ◽  
Vol 31 (4) ◽  
pp. 901-906 ◽  
Author(s):  
J. Hellegering ◽  
J. Visser ◽  
H. J. Kloke ◽  
F. C. H. D’Ancona ◽  
A. J. Hoitsma ◽  
...  


1995 ◽  
Vol 8 (6) ◽  
pp. 421-425 ◽  
Author(s):  
Yasuji Ichikawa ◽  
Mitsuo Hashimoto ◽  
Touru Hanafusa ◽  
Masahiro Kyo ◽  
Nobumasa Fujimoto ◽  
...  


2021 ◽  
Vol 10 (19) ◽  
pp. 4395
Author(s):  
Uwe Scheuermann ◽  
Sebastian Rademacher ◽  
Tristan Wagner ◽  
Andri Lederer ◽  
Hans-Michael Hau ◽  
...  

Aim: Complex arterial reconstruction in kidney transplantation (KT) using kidneys from deceased donors (DD) warrants additional study since little is known about the effects on the mid- and long-term outcome and graft survival. Methods: A total of 451 patients receiving deceased donor KT in our department between 1993 and 2017 were included in our study. Patients were divided into three groups according to the number of arteries and anastomosis: (A) 1 renal artery, 1 arterial anastomosis (N = 369); (B) >1 renal artery, 1 arterial anastomosis (N = 47); and (C) >1 renal artery, >1 arterial anastomosis (N = 35). Furthermore, the influence of localization of the arterial anastomosis (common iliac artery (CIA), versus non-CIA) was analyzed. Clinicopathological characteristics, outcome, and graft and patient survival of all groups were compared retrospectively. Results: With growing vascular complexity, the time of warm ischemia increased significantly (groups A, B, and C: 40 ± 19 min, 45 ± 19 min, and 50 ± 17 min, respectively; p = 0.006). Furthermore, the duration of operation was prolonged, although this did not reach significance (groups A, B, and C: 175 ± 98 min, 180 ± 35 min, and 210 ± 43 min, respectively; p = 0.352). There were no significant differences regarding surgical complications, post-transplant kidney function (delayed graft function, initial non-function, episodes of acute rejection), or long-term graft survival. Regarding the localization of the arterial anastomosis, non-CIA was an independent prognostic factor for deep vein thrombosis in multivariate analysis (CIA versus non-CIA: OR 11.551; 95% CI, 1.218–109.554; p = 0.033). Conclusion: Multiple-donor renal arteries should not be considered a contraindication to deceased KT, as morbidity rates and long-term outcomes seem to be comparable with grafts with single arteries and less complex anastomoses.





Surgery ◽  
1999 ◽  
Vol 125 (2) ◽  
pp. 155-159 ◽  
Author(s):  
Ty B. Dunn ◽  
Massimo Asolati ◽  
Dawn M. Holman ◽  
Vandad Raofi ◽  
Borko Jovanovic ◽  
...  


2000 ◽  
Vol 32 (7) ◽  
pp. 1828-1830 ◽  
Author(s):  
S.B Park ◽  
H.C Kim ◽  
H.T Kim ◽  
W.H Cho ◽  
C.H Park ◽  
...  


2012 ◽  
Vol 94 (10S) ◽  
pp. 1044
Author(s):  
K. Wu ◽  
B. Rudolph ◽  
L. Huber ◽  
D. Schmidt ◽  
L. Liefeldt ◽  
...  


Sign in / Sign up

Export Citation Format

Share Document