scholarly journals Prolonged-Release vs Immediate-Release Tacrolimus Capsules in Black vs White Kidney Transplant Patients: A Post Hoc Analysis of Phase III Data

2018 ◽  
Vol 50 (10) ◽  
pp. 3283-3295
Author(s):  
J.J. Schwartz ◽  
S. Wilson ◽  
F. Shi ◽  
D. Elsouda ◽  
N. Undre ◽  
...  
PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0191009 ◽  
Author(s):  
Daniel Constantino Yazbek ◽  
Aluizio Barbosa Carvalho ◽  
Cinara Sa Barros ◽  
Jose Osmar Medina Pestana ◽  
Carlos Eduardo Rochitte ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0197994 ◽  
Author(s):  
Mariel J. Hernandez ◽  
Luciene M. dos Reis ◽  
Igor D. Marques ◽  
Maria J. Araujo ◽  
Cesar A. M. Truyts ◽  
...  

2020 ◽  
Author(s):  
Cesar Margarit Ferri ◽  
Silvia Natoli ◽  
Paz Sanz-Ayan ◽  
Alberto Magni ◽  
Carlos Guerrero ◽  
...  

Aims: To investigate quality of life (QOL) and functionality changes in chronic pain during tapentadol prolonged release (PR) treatment. Patients & methods: Post hoc analysis of data from three Phase III trials in patients with osteoarthritis knee pain or low back pain. QOL and functionality changes were assessed by SF-36 scores. Results: All SF-36 subdomain scores improved progressively to week 3 of tapentadol titration and were sustained during 12-week maintenance treatment. Improvements in SF-36 scores were similar between tapentadol dose groups (e.g., 200 to <300 mg vs ≥500 mg), with no greater effect from higher doses. QOL and functionality improvements were consistently greater with tapentadol PR than oxycodone controlled release. Conclusion: Tapentadol PR provides consistent, clinically relevant improvements in QOL and functionality in chronic pain.


2016 ◽  
Vol 160 (3) ◽  
pp. 407-411 ◽  
Author(s):  
Karel Krejci ◽  
Josef Zadrazil ◽  
Eva Lackova ◽  
Zuzana Zilinska ◽  
Robert Roland ◽  
...  

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